BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 25466281)

  • 21. Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth.
    Wördehoff MM; Shaykhalishahi H; Groß L; Gremer L; Stoldt M; Buell AK; Willbold D; Hoyer W
    J Mol Biol; 2017 Oct; 429(20):3018-3030. PubMed ID: 28918091
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease.
    Gustot A; Gallea JI; Sarroukh R; Celej MS; Ruysschaert JM; Raussens V
    Biochem J; 2015 Nov; 471(3):323-33. PubMed ID: 26272943
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell.
    Matsuki A; Watanabe Y; Hashimoto S; Hoshino A; Matoba S
    Genes Cells; 2024 Apr; 29(4):328-336. PubMed ID: 38366711
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes.
    Izumi Y; Kondo N; Takahashi R; Akaike A; Kume T
    J Parkinsons Dis; 2016 Jun; 6(3):569-79. PubMed ID: 27314756
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death.
    Mahul-Mellier AL; Vercruysse F; Maco B; Ait-Bouziad N; De Roo M; Muller D; Lashuel HA
    Cell Death Differ; 2015 Dec; 22(12):2107-22. PubMed ID: 26138444
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Preserved proteinase K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study.
    Yoshinaga S; Yamanaka T; Miyazaki H; Okuzumi A; Hiyama A; Murayama S; Nukina N
    Biochem Biophys Res Commun; 2020 Feb; 522(3):655-661. PubMed ID: 31785806
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A sensitive assay reveals structural requirements for α-synuclein fibril growth.
    Dhavale DD; Tsai C; Bagchi DP; Engel LA; Sarezky J; Kotzbauer PT
    J Biol Chem; 2017 Jun; 292(22):9034-9050. PubMed ID: 28373279
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.
    Qiao L; Hamamichi S; Caldwell KA; Caldwell GA; Yacoubian TA; Wilson S; Xie ZL; Speake LD; Parks R; Crabtree D; Liang Q; Crimmins S; Schneider L; Uchiyama Y; Iwatsubo T; Zhou Y; Peng L; Lu Y; Standaert DG; Walls KC; Shacka JJ; Roth KA; Zhang J
    Mol Brain; 2008 Nov; 1():17. PubMed ID: 19021916
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Distinct alpha-Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH-SY5Y cells.
    Pantazopoulou M; Brembati V; Kanellidi A; Bousset L; Melki R; Stefanis L
    J Neurochem; 2021 Mar; 156(6):880-896. PubMed ID: 32869336
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates.
    Bae EJ; Yang NY; Lee C; Kim S; Lee HJ; Lee SJ
    Cell Death Dis; 2015 Oct; 6(10):e1901. PubMed ID: 26448324
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice.
    Karampetsou M; Ardah MT; Semitekolou M; Polissidis A; Samiotaki M; Kalomoiri M; Majbour N; Xanthou G; El-Agnaf OMA; Vekrellis K
    Sci Rep; 2017 Nov; 7(1):16533. PubMed ID: 29184069
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
    Chu Y; Dodiya H; Aebischer P; Olanow CW; Kordower JH
    Neurobiol Dis; 2009 Sep; 35(3):385-98. PubMed ID: 19505575
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology.
    Sacino AN; Brooks MM; Chakrabarty P; Saha K; Khoshbouei H; Golde TE; Giasson BI
    J Neurochem; 2017 Feb; 140(4):662-678. PubMed ID: 27424880
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of synucleinopathic seeding by rationally designed inhibitors.
    Sangwan S; Sahay S; Murray KA; Morgan S; Guenther EL; Jiang L; Williams CK; Vinters HV; Goedert M; Eisenberg DS
    Elife; 2020 Jan; 9():. PubMed ID: 31895037
    [TBL] [Abstract][Full Text] [Related]  

  • 35. α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.
    Dilsizoglu Senol A; Samarani M; Syan S; Guardia CM; Nonaka T; Liv N; Latour-Lambert P; Hasegawa M; Klumperman J; Bonifacino JS; Zurzolo C
    PLoS Biol; 2021 Jul; 19(7):e3001287. PubMed ID: 34283825
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Sequence- and seed-structure-dependent polymorphic fibrils of alpha-synuclein.
    Tanaka G; Yamanaka T; Furukawa Y; Kajimura N; Mitsuoka K; Nukina N
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1410-1420. PubMed ID: 30790619
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains.
    Peña-Díaz S; Pujols J; Vasili E; Pinheiro F; Santos J; Manglano-Artuñedo Z; Outeiro TF; Ventura S
    J Biol Chem; 2022 May; 298(5):101902. PubMed ID: 35390347
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
    Masliah E; Rockenstein E; Adame A; Alford M; Crews L; Hashimoto M; Seubert P; Lee M; Goldstein J; Chilcote T; Games D; Schenk D
    Neuron; 2005 Jun; 46(6):857-68. PubMed ID: 15953415
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson's disease.
    Rey NL; Steiner JA; Maroof N; Luk KC; Madaj Z; Trojanowski JQ; Lee VM; Brundin P
    J Exp Med; 2016 Aug; 213(9):1759-78. PubMed ID: 27503075
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein.
    Tsigelny IF; Bar-On P; Sharikov Y; Crews L; Hashimoto M; Miller MA; Keller SH; Platoshyn O; Yuan JX; Masliah E
    FEBS J; 2007 Apr; 274(7):1862-77. PubMed ID: 17381514
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.