87 related articles for article (PubMed ID: 25475209)
1. α-sarcin and RNase T1 based immunoconjugates: the role of intracellular trafficking in cytotoxic efficiency.
Tomé-Amat J; Ruiz-de-la-Herrán J; Martínez-del-Pozo Á; Gavilanes JG; Lacadena J
FEBS J; 2015 Feb; 282(4):673-84. PubMed ID: 25475209
[TBL] [Abstract][Full Text] [Related]
2. Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin.
Carreras-Sangrà N; Tomé-Amat J; García-Ortega L; Batt CA; Oñaderra M; Martínez-del-Pozo A; Gavilanes JG; Lacadena J
Protein Eng Des Sel; 2012 Aug; 25(8):425-35. PubMed ID: 22718791
[TBL] [Abstract][Full Text] [Related]
3. Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins.
Ruiz-de-la-Herrán J; Tomé-Amat J; Lázaro-Gorines R; Gavilanes JG; Lacadena J
Toxins (Basel); 2019 Oct; 11(10):. PubMed ID: 31614771
[TBL] [Abstract][Full Text] [Related]
4. Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A.
Tomé-Amat J; Herrero-Galán E; Oñaderra M; Martínez-Del-Pozo Á; Gavilanes JG; Lacadena J
FEBS J; 2015 Jun; 282(11):2131-41. PubMed ID: 25752204
[TBL] [Abstract][Full Text] [Related]
5. Tyr-48, a conserved residue in ribotoxins, is involved in the RNA-degrading activity of alpha-sarcin.
Alvarez-García E; García-Ortega L; Verdún Y; Bruix M; Martínez del Pozo A; Gavilanes JG
Biol Chem; 2006 May; 387(5):535-41. PubMed ID: 16740124
[TBL] [Abstract][Full Text] [Related]
6. Overproduction of fungal ribotoxin alpha-sarcin in Escherichia coli: generation of an active immunotoxin.
Rathore D; Nayak SK; Batra JK
Gene; 1997 Apr; 190(1):31-5. PubMed ID: 9185846
[TBL] [Abstract][Full Text] [Related]
7. Characterization of pKa values and titration shifts in the cytotoxic ribonuclease alpha-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function.
Pérez-Cañadillas JM; Campos-Olivas R; Lacadena J; Martínez del Pozo A; Gavilanes JG; Santoro J; Rico M; Bruix M
Biochemistry; 1998 Nov; 37(45):15865-76. PubMed ID: 9843392
[TBL] [Abstract][Full Text] [Related]
8. Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.
Masip M; García-Ortega L; Olmo N; García-Mayoral MF; Pérez-Cañadillas JM; Bruix M; Oñaderra M; Martínez del Pozo A; Gavilanes JG
Protein Sci; 2003 Jan; 12(1):161-9. PubMed ID: 12493839
[TBL] [Abstract][Full Text] [Related]
9. Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells.
Tomé-Amat J; Menéndez-Méndez A; García-Ortega L; Batt CA; Oñaderra M; Martínez-del-Pozo A; Gavilanes JG; Lacadena J
FEBS J; 2012 Sep; 279(17):3022-32. PubMed ID: 22748038
[TBL] [Abstract][Full Text] [Related]
10. RNase U2 and alpha-sarcin: a study of relationships.
Martínez-Ruiz A; García-Ortega L; Kao R; Lacadena J; Oñaderra M; Mancheño JM; Davies J; Martínez del Pozo A; Gavilanes JG
Methods Enzymol; 2001; 341():335-51. PubMed ID: 11582789
[No Abstract] [Full Text] [Related]
11. Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.
Garcia-Ortega L; Masip M; Mancheño JM; Oñaderra M; Lizarbe MA; García-Mayoral MF; Bruix M; Martínez del Pozo A; Gavilanes JG
J Biol Chem; 2002 May; 277(21):18632-9. PubMed ID: 11897788
[TBL] [Abstract][Full Text] [Related]
12. Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin alpha-sarcin.
Masip M; Lacadena J; Mancheño JM; Oñaderra M; Martínez-Ruiz A; Martínez del Pozo A; Gavilanes JG
Eur J Biochem; 2001 Dec; 268(23):6190-6. PubMed ID: 11733014
[TBL] [Abstract][Full Text] [Related]
13. Fungal ribotoxins: molecular dissection of a family of natural killers.
Lacadena J; Alvarez-García E; Carreras-Sangrà N; Herrero-Galán E; Alegre-Cebollada J; García-Ortega L; Oñaderra M; Gavilanes JG; Martínez del Pozo A
FEMS Microbiol Rev; 2007 Mar; 31(2):212-37. PubMed ID: 17253975
[TBL] [Abstract][Full Text] [Related]
14. Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.
Yuki S; Kondo Y; Kato F; Kato M; Matsuo N
Eur J Biochem; 2004 Sep; 271(17):3567-72. PubMed ID: 15317592
[TBL] [Abstract][Full Text] [Related]
15. Production and characterization of a monoclonal antibody against the ribosome inactivating protein alpha sarcin.
Ferreri AJ; Ferraris di Celle E; Caldera M; Muñoz S; Salvarelli S; Conde F; Canevari S; Tosi E; Colnaghi MI
Hybridoma; 1992 Aug; 11(4):437-46. PubMed ID: 1383124
[TBL] [Abstract][Full Text] [Related]
16. Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin alpha-sarcin.
Lacadena J; Martínez del Pozo A; Martínez-Ruiz A; Pérez-Cañadillas JM; Bruix M; Mancheño JM; Oñaderra M; Gavilanes JG
Proteins; 1999 Nov; 37(3):474-84. PubMed ID: 10591106
[TBL] [Abstract][Full Text] [Related]
17. The acidic ribosomal stalk proteins are not required for the highly specific inactivation exerted by α-sarcin of the eukaryotic ribosome.
Olombrada M; Rodríguez-Mateos M; Prieto D; Pla J; Remacha M; Martínez-del-Pozo A; Gavilanes JG; Ballesta JP; García-Ortega L
Biochemistry; 2014 Mar; 53(10):1545-7. PubMed ID: 24568582
[TBL] [Abstract][Full Text] [Related]
18. Dissecting structural and electrostatic interactions of charged groups in alpha-sarcin. An NMR study of some mutants involving the catalytic residues.
García-Mayoral MF; Pérez-Cañadillas JM; Santoro J; Ibarra-Molero B; Sanchez-Ruiz JM; Lacadena J; Martínez del Pozo A; Gavilanes JG; Rico M; Bruix M
Biochemistry; 2003 Nov; 42(45):13122-33. PubMed ID: 14609322
[TBL] [Abstract][Full Text] [Related]
19. Increase in nucleolytic activity of ribonuclease T1 by substitution of tryptophan 45 for tyrosine 45.
Nishikawa S; Morioka H; Kimura T; Ueda Y; Tanaka T; Uesugi S; Hakoshima T; Tomita K; Ohtsuka E; Ikehara M
Eur J Biochem; 1988 Apr; 173(2):389-94. PubMed ID: 3129293
[TBL] [Abstract][Full Text] [Related]
20. Molecular dynamics simulations of ribonuclease T1: comparison of the free enzyme and the 2' GMP-enzyme complex.
MacKerell AD; Nilsson L; Rigler R; Heinemann U; Saenger W
Proteins; 1989; 6(1):20-31. PubMed ID: 2558378
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]