253 related articles for article (PubMed ID: 25476449)
1. Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P; Mori M; Alfonsi R; Ghirga F; Aiello F; Toscano S; Ingallina C; Siler M; Cucchi D; Po A; Miele E; D'Amico D; Canettieri G; De Smaele E; Ferretti E; Screpanti I; Uccello Barretta G; Botta M; Botta B; Gulino A; Di Marcotullio L
EMBO J; 2015 Jan; 34(2):200-17. PubMed ID: 25476449
[TBL] [Abstract][Full Text] [Related]
2. Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.
Lipinski RJ; Gipp JJ; Zhang J; Doles JD; Bushman W
Exp Cell Res; 2006 Jul; 312(11):1925-38. PubMed ID: 16571352
[TBL] [Abstract][Full Text] [Related]
3. Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier.
Rohner A; Spilker ME; Lam JL; Pascual B; Bartkowski D; Li QJ; Yang AH; Stevens G; Xu M; Wells PA; Planken S; Nair S; Sun S
Mol Cancer Ther; 2012 Jan; 11(1):57-65. PubMed ID: 22084163
[TBL] [Abstract][Full Text] [Related]
4. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.
Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ
J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313
[TBL] [Abstract][Full Text] [Related]
5. GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.
Hu MC; Mo R; Bhella S; Wilson CW; Chuang PT; Hui CC; Rosenblum ND
Development; 2006 Feb; 133(3):569-78. PubMed ID: 16396903
[TBL] [Abstract][Full Text] [Related]
6. Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin.
Makinodan E; Marneros AG
Exp Dermatol; 2012 Nov; 21(11):847-52. PubMed ID: 23163650
[TBL] [Abstract][Full Text] [Related]
7. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.
Manetti F; Petricci E
Expert Opin Ther Pat; 2016; 26(4):529-35. PubMed ID: 26666870
[TBL] [Abstract][Full Text] [Related]
9. Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.
Svärd J; Heby-Henricson K; Persson-Lek M; Rozell B; Lauth M; Bergström A; Ericson J; Toftgård R; Teglund S
Dev Cell; 2006 Feb; 10(2):187-97. PubMed ID: 16459298
[TBL] [Abstract][Full Text] [Related]
10. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
[TBL] [Abstract][Full Text] [Related]
11. Expression of Sonic hedgehog during cell proliferation in the human cerebellum.
Haldipur P; Bharti U; Govindan S; Sarkar C; Iyengar S; Gressens P; Mani S
Stem Cells Dev; 2012 May; 21(7):1059-68. PubMed ID: 21732818
[TBL] [Abstract][Full Text] [Related]
12. Sonic hedgehog stimulates mouse embryonic stem cell proliferation by cooperation of Ca2+/protein kinase C and epidermal growth factor receptor as well as Gli1 activation.
Heo JS; Lee MY; Han HJ
Stem Cells; 2007 Dec; 25(12):3069-80. PubMed ID: 17901397
[TBL] [Abstract][Full Text] [Related]
13. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
Wellbrock J; Latuske E; Köhler J; Wagner K; Stamm H; Vettorazzi E; Vohwinkel G; Klokow M; Uibeleisen R; Ehm P; Riecken K; Loges S; Thol F; Schubert C; Amling M; Jücker M; Bokemeyer C; Heuser M; Krauter J; Fiedler W
Clin Cancer Res; 2015 May; 21(10):2388-98. PubMed ID: 25745035
[TBL] [Abstract][Full Text] [Related]
14. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
[TBL] [Abstract][Full Text] [Related]
15. Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
Barsoum I; Yao HH
Biol Reprod; 2011 May; 84(5):894-9. PubMed ID: 21209421
[TBL] [Abstract][Full Text] [Related]
16. Cell signaling. A ciliary signaling switch.
Christensen ST; Ott CM
Science; 2007 Jul; 317(5836):330-1. PubMed ID: 17641189
[No Abstract] [Full Text] [Related]
17. Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors.
Merchant A; Joseph G; Wang Q; Brennan S; Matsui W
Blood; 2010 Mar; 115(12):2391-6. PubMed ID: 20107231
[TBL] [Abstract][Full Text] [Related]
18. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
[TBL] [Abstract][Full Text] [Related]
19. Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.
Dagklis A; Pauwels D; Lahortiga I; Geerdens E; Bittoun E; Cauwelier B; Tousseyn T; Uyttebroeck A; Maertens J; Verhoef G; Vandenberghe P; Cools J
Haematologica; 2015 Mar; 100(3):e102-5. PubMed ID: 25527561
[No Abstract] [Full Text] [Related]
20. The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma.
Tang L; Tan YX; Jiang BG; Pan YF; Li SX; Yang GZ; Wang M; Wang Q; Zhang J; Zhou WP; Dong LW; Wang HY
Clin Cancer Res; 2013 Apr; 19(8):2014-24. PubMed ID: 23493353
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]