377 related articles for article (PubMed ID: 25481013)
1. Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.
Wang Q; Xiao B; Cui S; Song H; Qian Y; Dong L; An H; Cui Y; Zhang W; He Y; Zhang J; Yang J; Zhang F; Hu G; Gong X; Yan Z; Zheng Y; Wang X
Dis Model Mech; 2014 Dec; 7(12):1385-95. PubMed ID: 25481013
[TBL] [Abstract][Full Text] [Related]
2. Triptolide Rescues Spatial Memory Deficits and Amyloid-β Aggregation Accompanied by Inhibition of Inflammatory Responses and MAPKs Activity in APP/PS1 Transgenic Mice.
Cui YQ; Wang Q; Zhang DM; Wang JY; Xiao B; Zheng Y; Wang XM
Curr Alzheimer Res; 2016; 13(3):288-96. PubMed ID: 26906357
[TBL] [Abstract][Full Text] [Related]
3. [Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice].
Li H; Liu MF; Liu JG; Liu LT; Guan J; Cai LL; Hu J; Wei Y
Zhongguo Zhong Xi Yi Jie He Za Zhi; 2013 Jan; 33(1):90-4. PubMed ID: 23596795
[TBL] [Abstract][Full Text] [Related]
4. Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
Devi L; Ohno M
Neuroscience; 2015 Oct; 307():128-37. PubMed ID: 26314636
[TBL] [Abstract][Full Text] [Related]
5. Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.
Zeng Y; Zhang J; Zhu Y; Zhang J; Shen H; Lu J; Pan X; Lin N; Dai X; Zhou M; Chen X
J Neurochem; 2015 Apr; 133(1):38-52. PubMed ID: 25661995
[TBL] [Abstract][Full Text] [Related]
6. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
[TBL] [Abstract][Full Text] [Related]
7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
8. Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease.
Cheng S; LeBlanc KJ; Li L
PLoS One; 2014; 9(9):e108845. PubMed ID: 25275487
[TBL] [Abstract][Full Text] [Related]
9. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
[TBL] [Abstract][Full Text] [Related]
10. Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.
Durairajan SS; Liu LF; Lu JH; Chen LL; Yuan Q; Chung SK; Huang L; Li XS; Huang JD; Li M
Neurobiol Aging; 2012 Dec; 33(12):2903-19. PubMed ID: 22459600
[TBL] [Abstract][Full Text] [Related]
11. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Devi L; Ohno M
Eur J Neurosci; 2010 Jan; 31(1):110-8. PubMed ID: 20092558
[TBL] [Abstract][Full Text] [Related]
12. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
Dorresteijn B; Rotman M; Faber D; Schravesande R; Suidgeest E; van der Weerd L; van der Maarel SM; Verrips CT; El Khattabi M
FEBS J; 2015 Sep; 282(18):3618-31. PubMed ID: 26147692
[TBL] [Abstract][Full Text] [Related]
13. Effects of triptolide on the synaptophysin expression of hippocampal neurons in the AD cellular model.
Nie J; Zhou M; Lü C; Hu X; Wan B; Yang B; Li Y
Int Immunopharmacol; 2012 Jun; 13(2):175-80. PubMed ID: 22498763
[TBL] [Abstract][Full Text] [Related]
14. Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25-35-treated differentiated PC12 cells.
Xu P; Wang H; Li Z; Yang Z
Life Sci; 2016 Jan; 145():19-26. PubMed ID: 26679104
[TBL] [Abstract][Full Text] [Related]
15. Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice.
Sun C; Qiu X; Wang Y; Liu J; Li Q; Jiang H; Li S; Song C
Neurosci Lett; 2020 Sep; 735():135192. PubMed ID: 32619650
[TBL] [Abstract][Full Text] [Related]
16. Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.
Katsouri L; Ashraf A; Birch AM; Lee KK; Mirzaei N; Sastre M
Neurobiol Aging; 2015 Feb; 36(2):821-31. PubMed ID: 25457554
[TBL] [Abstract][Full Text] [Related]
17. BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice.
Ohno M; Cole SL; Yasvoina M; Zhao J; Citron M; Berry R; Disterhoft JF; Vassar R
Neurobiol Dis; 2007 Apr; 26(1):134-45. PubMed ID: 17258906
[TBL] [Abstract][Full Text] [Related]
18. An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation.
Cai Y; Xue ZQ; Zhang XM; Li MB; Wang H; Luo XG; Cai H; Yan XX
Neuroscience; 2012 Jul; 215():160-73. PubMed ID: 22542680
[TBL] [Abstract][Full Text] [Related]
19. [Effect of hyperforin on learning and memory abilities and Aβ₁₋₄₂, βAPP and BACE1 protein expressions in hippocampus of Alzheimer's disease model mice].
Geng YN; Wu YJ; Zhang WX
Zhongguo Zhong Yao Za Zhi; 2016 Aug; 41(15):2877-2882. PubMed ID: 28914032
[TBL] [Abstract][Full Text] [Related]
20. 2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.
Zhu Z; Li C; Wang X; Yang Z; Chen J; Hu L; Jiang H; Shen X
J Neurochem; 2010 Jul; 114(2):374-85. PubMed ID: 20412384
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
