These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 25481013)

  • 1. Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.
    Wang Q; Xiao B; Cui S; Song H; Qian Y; Dong L; An H; Cui Y; Zhang W; He Y; Zhang J; Yang J; Zhang F; Hu G; Gong X; Yan Z; Zheng Y; Wang X
    Dis Model Mech; 2014 Dec; 7(12):1385-95. PubMed ID: 25481013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Triptolide Rescues Spatial Memory Deficits and Amyloid-β Aggregation Accompanied by Inhibition of Inflammatory Responses and MAPKs Activity in APP/PS1 Transgenic Mice.
    Cui YQ; Wang Q; Zhang DM; Wang JY; Xiao B; Zheng Y; Wang XM
    Curr Alzheimer Res; 2016; 13(3):288-96. PubMed ID: 26906357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice].
    Li H; Liu MF; Liu JG; Liu LT; Guan J; Cai LL; Hu J; Wei Y
    Zhongguo Zhong Xi Yi Jie He Za Zhi; 2013 Jan; 33(1):90-4. PubMed ID: 23596795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
    Devi L; Ohno M
    Neuroscience; 2015 Oct; 307():128-37. PubMed ID: 26314636
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.
    Zeng Y; Zhang J; Zhu Y; Zhang J; Shen H; Lu J; Pan X; Lin N; Dai X; Zhou M; Chen X
    J Neurochem; 2015 Apr; 133(1):38-52. PubMed ID: 25661995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease.
    Cheng S; LeBlanc KJ; Li L
    PLoS One; 2014; 9(9):e108845. PubMed ID: 25275487
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
    Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
    Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.
    Durairajan SS; Liu LF; Lu JH; Chen LL; Yuan Q; Chung SK; Huang L; Li XS; Huang JD; Li M
    Neurobiol Aging; 2012 Dec; 33(12):2903-19. PubMed ID: 22459600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
    Devi L; Ohno M
    Eur J Neurosci; 2010 Jan; 31(1):110-8. PubMed ID: 20092558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
    Dorresteijn B; Rotman M; Faber D; Schravesande R; Suidgeest E; van der Weerd L; van der Maarel SM; Verrips CT; El Khattabi M
    FEBS J; 2015 Sep; 282(18):3618-31. PubMed ID: 26147692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of triptolide on the synaptophysin expression of hippocampal neurons in the AD cellular model.
    Nie J; Zhou M; Lü C; Hu X; Wan B; Yang B; Li Y
    Int Immunopharmacol; 2012 Jun; 13(2):175-80. PubMed ID: 22498763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25-35-treated differentiated PC12 cells.
    Xu P; Wang H; Li Z; Yang Z
    Life Sci; 2016 Jan; 145():19-26. PubMed ID: 26679104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice.
    Sun C; Qiu X; Wang Y; Liu J; Li Q; Jiang H; Li S; Song C
    Neurosci Lett; 2020 Sep; 735():135192. PubMed ID: 32619650
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.
    Katsouri L; Ashraf A; Birch AM; Lee KK; Mirzaei N; Sastre M
    Neurobiol Aging; 2015 Feb; 36(2):821-31. PubMed ID: 25457554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice.
    Ohno M; Cole SL; Yasvoina M; Zhao J; Citron M; Berry R; Disterhoft JF; Vassar R
    Neurobiol Dis; 2007 Apr; 26(1):134-45. PubMed ID: 17258906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation.
    Cai Y; Xue ZQ; Zhang XM; Li MB; Wang H; Luo XG; Cai H; Yan XX
    Neuroscience; 2012 Jul; 215():160-73. PubMed ID: 22542680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Effect of hyperforin on learning and memory abilities and Aβ₁₋₄₂, βAPP and BACE1 protein expressions in hippocampus of Alzheimer's disease model mice].
    Geng YN; Wu YJ; Zhang WX
    Zhongguo Zhong Yao Za Zhi; 2016 Aug; 41(15):2877-2882. PubMed ID: 28914032
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.
    Zhu Z; Li C; Wang X; Yang Z; Chen J; Hu L; Jiang H; Shen X
    J Neurochem; 2010 Jul; 114(2):374-85. PubMed ID: 20412384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.