BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

606 related articles for article (PubMed ID: 25482556)

  • 1. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
    Rampal R; Alkalin A; Madzo J; Vasanthakumar A; Pronier E; Patel J; Li Y; Ahn J; Abdel-Wahab O; Shih A; Lu C; Ward PS; Tsai JJ; Hricik T; Tosello V; Tallman JE; Zhao X; Daniels D; Dai Q; Ciminio L; Aifantis I; He C; Fuks F; Tallman MS; Ferrando A; Nimer S; Paietta E; Thompson CB; Licht JD; Mason CE; Godley LA; Melnick A; Figueroa ME; Levine RL
    Cell Rep; 2014 Dec; 9(5):1841-1855. PubMed ID: 25482556
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
    Wang Y; Xiao M; Chen X; Chen L; Xu Y; Lv L; Wang P; Yang H; Ma S; Lin H; Jiao B; Ren R; Ye D; Guan KL; Xiong Y
    Mol Cell; 2015 Feb; 57(4):662-673. PubMed ID: 25601757
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunohistochemical loss of 5-hydroxymethylcytosine expression in acute myeloid leukaemia: relationship to somatic gene mutations affecting epigenetic pathways.
    Magotra M; Sakhdari A; Lee PJ; Tomaszewicz K; Dresser K; Hutchinson LM; Woda BA; Chen BJ
    Histopathology; 2016 Dec; 69(6):1055-1065. PubMed ID: 27458708
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-Hydroxymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia.
    Ahn JS; Kim HJ; Kim YK; Lee SS; Ahn SY; Jung SH; Yang DH; Lee JJ; Park HJ; Choi SH; Jung CW; Jang JH; Kim HJ; Moon JH; Sohn SK; Won JH; Kim SH; Michael S; Minden MD; Kim DD
    Oncotarget; 2017 Jan; 8(5):8305-8314. PubMed ID: 28039446
    [TBL] [Abstract][Full Text] [Related]  

  • 5.
    Pasca S; Jurj A; Tomuleasa C; Zdrenghea M
    Medicina (Kaunas); 2020 Nov; 56(12):. PubMed ID: 33255417
    [No Abstract]   [Full Text] [Related]  

  • 6. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
    Figueroa ME; Abdel-Wahab O; Lu C; Ward PS; Patel J; Shih A; Li Y; Bhagwat N; Vasanthakumar A; Fernandez HF; Tallman MS; Sun Z; Wolniak K; Peeters JK; Liu W; Choe SE; Fantin VR; Paietta E; Löwenberg B; Licht JD; Godley LA; Delwel R; Valk PJ; Thompson CB; Levine RL; Melnick A
    Cancer Cell; 2010 Dec; 18(6):553-67. PubMed ID: 21130701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of acute myeloid leukemia based on levels of global hydroxymethylation.
    Kroeze LI; Aslanyan MG; van Rooij A; Koorenhof-Scheele TN; Massop M; Carell T; Boezeman JB; Marie JP; Halkes CJ; de Witte T; Huls G; Suciu S; Wevers RA; van der Reijden BA; Jansen JH;
    Blood; 2014 Aug; 124(7):1110-8. PubMed ID: 24986689
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.
    Putiri EL; Tiedemann RL; Thompson JJ; Liu C; Ho T; Choi JH; Robertson KD
    Genome Biol; 2014 Jun; 15(6):R81. PubMed ID: 24958354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial.
    Aslanyan MG; Kroeze LI; Langemeijer SM; Koorenhof-Scheele TN; Massop M; van Hoogen P; Stevens-Linders E; van de Locht LT; Tönnissen E; van der Heijden A; da Silva-Coelho P; Cilloni D; Saglio G; Marie JP; Tang R; Labar B; Amadori S; Muus P; Willemze R; Marijt EW; de Witte T; van der Reijden BA; Suciu S; Jansen JH
    Ann Hematol; 2014 Aug; 93(8):1401-12. PubMed ID: 24994606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.
    Rocquain J; Carbuccia N; Trouplin V; Raynaud S; Murati A; Nezri M; Tadrist Z; Olschwang S; Vey N; Birnbaum D; Gelsi-Boyer V; Mozziconacci MJ
    BMC Cancer; 2010 Aug; 10():401. PubMed ID: 20678218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
    Ko M; Huang Y; Jankowska AM; Pape UJ; Tahiliani M; Bandukwala HS; An J; Lamperti ED; Koh KP; Ganetzky R; Liu XS; Aravind L; Agarwal S; Maciejewski JP; Rao A
    Nature; 2010 Dec; 468(7325):839-43. PubMed ID: 21057493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytosine 5-hydroxymethylation regulated kit gene expression in acute myeloid leukemia.
    Xue YM; Cheng HC; Wang JH; Wang W; Miao L
    J Biol Regul Homeost Agents; 2019; 33(2):345-353. PubMed ID: 30972998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2.
    Buscarlet M; Tessier A; Provost S; Mollica L; Busque L
    Exp Hematol; 2016 Nov; 44(11):1072-1084. PubMed ID: 27475703
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.
    Poole CJ; Lodh A; Choi JH; van Riggelen J
    Epigenetics Chromatin; 2019 Jul; 12(1):41. PubMed ID: 31266538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Classification of Acute Myeloid Leukemia by Cell-Free DNA 5-Hydroxymethylcytosine.
    Shao J; Shah S; Ganguly S; Zu Y; He C; Li Z
    Genes (Basel); 2023 May; 14(6):. PubMed ID: 37372359
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TET2 as an epigenetic master regulator for normal and malignant hematopoiesis.
    Nakajima H; Kunimoto H
    Cancer Sci; 2014 Sep; 105(9):1093-9. PubMed ID: 25040794
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new path to leukemia with WIT.
    Sardina JL; Graf T
    Mol Cell; 2015 Feb; 57(4):573-574. PubMed ID: 25699704
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients.
    Atef M; Shafik NF; H A Hassan N; Allam RM; El-Meligui YM; Abdelaziz H
    Asian Pac J Cancer Prev; 2023 Sep; 24(9):3169-3182. PubMed ID: 37774069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.
    Huang Y; Chavez L; Chang X; Wang X; Pastor WA; Kang J; Zepeda-Martínez JA; Pape UJ; Jacobsen SE; Peters B; Rao A
    Proc Natl Acad Sci U S A; 2014 Jan; 111(4):1361-6. PubMed ID: 24474761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients.
    Lagos C; Carvajal P; Castro I; Jara D; González S; Aguilera S; Barrera MJ; Quest AFG; Bahamondes V; Molina C; Urzúa U; Hermoso MA; Leyton C; González MJ
    Clin Immunol; 2018 Nov; 196():85-96. PubMed ID: 29894742
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.