479 related articles for article (PubMed ID: 25482947)
1. mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels.
Goudarzi KM; Nistér M; Lindström MS
Cancer Biol Ther; 2014; 15(11):1499-514. PubMed ID: 25482947
[TBL] [Abstract][Full Text] [Related]
2. Nucleolar Stress Response via Ribosomal Protein L11 Regulates Topoisomerase Inhibitor Sensitivity of P53-Intact Cancers.
Ishihara Y; Nakamura K; Nakagawa S; Okamoto Y; Yamamoto M; Furukawa T; Kawahara K
Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555627
[TBL] [Abstract][Full Text] [Related]
3. PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
Chen H; Han L; Tsai H; Wang Z; Wu Y; Duo Y; Cao W; Chen L; Tan Z; Xu N; Huang X; Zhuang J; Huang L
Oncotarget; 2016 Dec; 7(50):83241-83257. PubMed ID: 27829214
[TBL] [Abstract][Full Text] [Related]
4. Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.
Turi Z; Senkyrikova M; Mistrik M; Bartek J; Moudry P
Cell Cycle; 2018; 17(1):92-101. PubMed ID: 29143558
[TBL] [Abstract][Full Text] [Related]
5. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway.
Havel JJ; Li Z; Cheng D; Peng J; Fu H
Oncogene; 2015 Mar; 34(12):1487-98. PubMed ID: 24704832
[TBL] [Abstract][Full Text] [Related]
6. Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells.
Wang HT; Chen TY; Weng CW; Yang CH; Tang MS
Oncotarget; 2016 Dec; 7(49):80450-80464. PubMed ID: 27741518
[TBL] [Abstract][Full Text] [Related]
7. Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.
Bursać S; Brdovčak MC; Pfannkuchen M; Orsolić I; Golomb L; Zhu Y; Katz C; Daftuar L; Grabušić K; Vukelić I; Filić V; Oren M; Prives C; Volarevic S
Proc Natl Acad Sci U S A; 2012 Dec; 109(50):20467-72. PubMed ID: 23169665
[TBL] [Abstract][Full Text] [Related]
8. Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.
Mahata B; Sundqvist A; Xirodimas DP
Oncogene; 2012 Jun; 31(25):3060-71. PubMed ID: 22081073
[TBL] [Abstract][Full Text] [Related]
9. Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways.
Liu QJ; Shen HL; Lin J; Xu XH; Ji ZG; Han X; Shang DH; Yang PQ
Drug Des Devel Ther; 2016; 10():745-55. PubMed ID: 26937175
[TBL] [Abstract][Full Text] [Related]
10. GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
Kayama K; Watanabe S; Takafuji T; Tsuji T; Hironaka K; Matsumoto M; Nakayama KI; Enari M; Kohno T; Shiraishi K; Kiyono T; Yoshida K; Sugimoto N; Fujita M
EMBO Rep; 2017 Jan; 18(1):123-137. PubMed ID: 27856536
[TBL] [Abstract][Full Text] [Related]
11. Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.
Wang B; Gao J; Zhao Z; Zhong X; Cui H; Hou H; Zhang Y; Zheng J; Di J; Liu Y
Mol Med; 2022 Sep; 28(1):109. PubMed ID: 36071402
[TBL] [Abstract][Full Text] [Related]
12. Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.
Nagata Y; Takahashi A; Ohnishi K; Ota I; Ohnishi T; Tojo T; Taniguchi S
Int J Oncol; 2010 Oct; 37(4):1001-10. PubMed ID: 20811722
[TBL] [Abstract][Full Text] [Related]
13. Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction.
Fumagalli S; Di Cara A; Neb-Gulati A; Natt F; Schwemberger S; Hall J; Babcock GF; Bernardi R; Pandolfi PP; Thomas G
Nat Cell Biol; 2009 Apr; 11(4):501-8. PubMed ID: 19287375
[TBL] [Abstract][Full Text] [Related]
14. The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases.
Zajkowicz A; Rusin M
Mech Ageing Dev; 2011; 132(11-12):543-51. PubMed ID: 21945951
[TBL] [Abstract][Full Text] [Related]
15. A new PICTure of nucleolar stress.
Suzuki A; Kogo R; Kawahara K; Sasaki M; Nishio M; Maehama T; Sasaki T; Mimori K; Mori M
Cancer Sci; 2012 Apr; 103(4):632-7. PubMed ID: 22320853
[TBL] [Abstract][Full Text] [Related]
16. The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells.
Dong Z; Zhu C; Zhan Q; Jiang W
Oncotarget; 2017 Feb; 8(8):13240-13252. PubMed ID: 28099941
[TBL] [Abstract][Full Text] [Related]
17. Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells.
Daniele S; Costa B; Zappelli E; Da Pozzo E; Sestito S; Nesi G; Campiglia P; Marinelli L; Novellino E; Rapposelli S; Martini C
Sci Rep; 2015 Apr; 5():9956. PubMed ID: 25898313
[TBL] [Abstract][Full Text] [Related]
18. HEY1 functions are regulated by its phosphorylation at Ser-68.
López-Mateo I; Arruabarrena-Aristorena A; Artaza-Irigaray C; López JA; Calvo E; Belandia B
Biosci Rep; 2016 Jul; 36(3):. PubMed ID: 27129302
[TBL] [Abstract][Full Text] [Related]
19. Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Sasaki M; Kawahara K; Nishio M; Mimori K; Kogo R; Hamada K; Itoh B; Wang J; Komatsu Y; Yang YR; Hikasa H; Horie Y; Yamashita T; Kamijo T; Zhang Y; Zhu Y; Prives C; Nakano T; Mak TW; Sasaki T; Maehama T; Mori M; Suzuki A
Nat Med; 2011 Jul; 17(8):944-51. PubMed ID: 21804542
[TBL] [Abstract][Full Text] [Related]
20. Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53.
Russo A; Pagliara V; Albano F; Esposito D; Sagar V; Loreni F; Irace C; Santamaria R; Russo G
Cell Cycle; 2016; 15(1):41-51. PubMed ID: 26636733
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
