234 related articles for article (PubMed ID: 25483186)
1. Keap1 modulates the redox cycle and hepatocyte cell cycle in regenerating liver.
Hu M; Zou Y; Nambiar SM; Lee J; Yang Y; Dai G
Cell Cycle; 2014; 13(15):2349-58. PubMed ID: 25483186
[TBL] [Abstract][Full Text] [Related]
2. Nrf2 is essential for timely M phase entry of replicating hepatocytes during liver regeneration.
Zou Y; Hu M; Lee J; Nambiar SM; Garcia V; Bao Q; Chan JY; Dai G
Am J Physiol Gastrointest Liver Physiol; 2015 Feb; 308(4):G262-8. PubMed ID: 25524062
[TBL] [Abstract][Full Text] [Related]
3. Dynamic and coordinated regulation of KEAP1-NRF2-ARE and p53/p21 signaling pathways is associated with acetaminophen injury responsive liver regeneration.
Fan X; Chen P; Tan H; Zeng H; Jiang Y; Wang Y; Wang Y; Hou X; Bi H; Huang M
Drug Metab Dispos; 2014 Sep; 42(9):1532-9. PubMed ID: 25002747
[TBL] [Abstract][Full Text] [Related]
4. Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1.
Cheng Q; Taguchi K; Aleksunes LM; Manautou JE; Cherrington NJ; Yamamoto M; Slitt AL
J Biochem Mol Toxicol; 2011; 25(5):320-9. PubMed ID: 21538727
[TBL] [Abstract][Full Text] [Related]
5. Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.
Okawa H; Motohashi H; Kobayashi A; Aburatani H; Kensler TW; Yamamoto M
Biochem Biophys Res Commun; 2006 Jan; 339(1):79-88. PubMed ID: 16293230
[TBL] [Abstract][Full Text] [Related]
6. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
Reisman SA; Yeager RL; Yamamoto M; Klaassen CD
Toxicol Sci; 2009 Mar; 108(1):35-47. PubMed ID: 19129213
[TBL] [Abstract][Full Text] [Related]
7. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis.
Mohs A; Otto T; Schneider KM; Peltzer M; Boekschoten M; Holland CH; Hudert CA; Kalveram L; Wiegand S; Saez-Rodriguez J; Longerich T; Hengstler JG; Trautwein C
J Hepatol; 2021 Mar; 74(3):638-648. PubMed ID: 33342543
[TBL] [Abstract][Full Text] [Related]
8. Circadian clock core component Bmal1 dictates cell cycle rhythm of proliferating hepatocytes during liver regeneration.
Jiang H; Garcia V; Yanum JA; Lee J; Dai G
Am J Physiol Gastrointest Liver Physiol; 2021 Oct; 321(4):G389-G399. PubMed ID: 34431407
[TBL] [Abstract][Full Text] [Related]
9. Deregulation of growth factor, circadian clock, and cell cycle signaling in regenerating hepatocyte RXRalpha-deficient mouse livers.
Yang X; Guo M; Wan YJ
Am J Pathol; 2010 Feb; 176(2):733-43. PubMed ID: 20035057
[TBL] [Abstract][Full Text] [Related]
10. Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.
Slocum SL; Skoko JJ; Wakabayashi N; Aja S; Yamamoto M; Kensler TW; Chartoumpekis DV
Arch Biochem Biophys; 2016 Feb; 591():57-65. PubMed ID: 26701603
[TBL] [Abstract][Full Text] [Related]
11. NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice.
Shirasaki K; Taguchi K; Unno M; Motohashi H; Yamamoto M
Hepatology; 2014 Jun; 59(6):2371-82. PubMed ID: 24443206
[TBL] [Abstract][Full Text] [Related]
12. Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.
Reisman SA; Csanaky IL; Aleksunes LM; Klaassen CD
Toxicol Sci; 2009 May; 109(1):31-40. PubMed ID: 19246624
[TBL] [Abstract][Full Text] [Related]
13. Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.
Soares MA; Cohen OD; Low YC; Sartor RA; Ellison T; Anil U; Anzai L; Chang JB; Saadeh PB; Rabbani PS; Ceradini DJ
Diabetes; 2016 Mar; 65(3):633-46. PubMed ID: 26647385
[TBL] [Abstract][Full Text] [Related]
14. Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Toyama T; Sumi D; Shinkai Y; Yasutake A; Taguchi K; Tong KI; Yamamoto M; Kumagai Y
Biochem Biophys Res Commun; 2007 Nov; 363(3):645-50. PubMed ID: 17904103
[TBL] [Abstract][Full Text] [Related]
15. Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Yates MS; Tran QT; Dolan PM; Osburn WO; Shin S; McCulloch CC; Silkworth JB; Taguchi K; Yamamoto M; Williams CR; Liby KT; Sporn MB; Sutter TR; Kensler TW
Carcinogenesis; 2009 Jun; 30(6):1024-31. PubMed ID: 19386581
[TBL] [Abstract][Full Text] [Related]
16. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis.
Cazanave SC; Wang X; Zhou H; Rahmani M; Grant S; Durrant DE; Klaassen CD; Yamamoto M; Sanyal AJ
Cell Death Differ; 2014 Aug; 21(8):1303-12. PubMed ID: 24769730
[TBL] [Abstract][Full Text] [Related]
17. Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin.
Nevzorova YA; Tschaharganeh D; Gassler N; Geng Y; Weiskirchen R; Sicinski P; Trautwein C; Liedtke C
Gastroenterology; 2009 Aug; 137(2):691-703, 703.e1-6. PubMed ID: 19445941
[TBL] [Abstract][Full Text] [Related]
18. Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.
Luo L; Chen Y; Wu D; Shou J; Wang S; Ye J; Tang X; Wang XJ
Toxicol Appl Pharmacol; 2015 Nov; 288(3):339-48. PubMed ID: 26291391
[TBL] [Abstract][Full Text] [Related]
19. Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.
Wu KC; Cui JY; Klaassen CD
PLoS One; 2012; 7(7):e39006. PubMed ID: 22808024
[TBL] [Abstract][Full Text] [Related]
20. Nrf2 protects against furosemide-induced hepatotoxicity.
Qu Q; Liu J; Zhou HH; Klaassen CD
Toxicology; 2014 Oct; 324():35-42. PubMed ID: 24813929
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]