These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 25485739)

  • 1. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.
    Wang M; Fuhrmann J; Thompson PR
    Biochemistry; 2014 Dec; 53(50):7884-92. PubMed ID: 25485739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
    Burgos ES; Wilczek C; Onikubo T; Bonanno JB; Jansong J; Reimer U; Shechter D
    J Biol Chem; 2015 Apr; 290(15):9674-89. PubMed ID: 25713080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity, processivity, and kinetic mechanism of protein arginine methyltransferase 5.
    Wang M; Xu RM; Thompson PR
    Biochemistry; 2013 Aug; 52(32):5430-40. PubMed ID: 23866019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
    Stopa N; Krebs JE; Shechter D
    Cell Mol Life Sci; 2015 Jun; 72(11):2041-59. PubMed ID: 25662273
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
    Saha K; Adhikary G; Eckert RL
    J Invest Dermatol; 2016 Jan; 136(1):214-224. PubMed ID: 26763441
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
    Chen H; Lorton B; Gupta V; Shechter D
    Oncogene; 2017 Jan; 36(3):373-386. PubMed ID: 27270440
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lead induces the up-regulation of the protein arginine methyltransferase 5 possibly by its promoter demethylation.
    Ghosh K; Chatterjee B; Kanade SR
    Biochem J; 2018 Aug; 475(16):2653-2666. PubMed ID: 30054435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.
    Saha K; Eckert RL
    J Biol Chem; 2015 May; 290(21):13521-30. PubMed ID: 25851901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.
    Mongiardi MP; Savino M; Bartoli L; Beji S; Nanni S; Scagnoli F; Falchetti ML; Favia A; Farsetti A; Levi A; Nasi S; Illi B
    Sci Rep; 2015 Nov; 5():15494. PubMed ID: 26563484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype.
    Ezeka G; Adhikary G; Kandasamy S; Friedberg JS; Eckert RL
    Mol Carcinog; 2021 Jul; 60(7):429-439. PubMed ID: 33872411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.
    Guderian G; Peter C; Wiesner J; Sickmann A; Schulze-Osthoff K; Fischer U; Grimmler M
    J Biol Chem; 2011 Jan; 286(3):1976-86. PubMed ID: 21081503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Structure and Function of the PRMT5:MEP50 Complex.
    Antonysamy S
    Subcell Biochem; 2017; 83():185-194. PubMed ID: 28271477
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Structural Effects of Phosphorylation of Protein Arginine Methyltransferase 5 on Its Binding to Histone H4.
    Börzsei R; Bayarsaikhan B; Zsidó BZ; Lontay B; Hetényi C
    Int J Mol Sci; 2022 Sep; 23(19):. PubMed ID: 36232624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of mep50 in adult and embryos of medaka fish (Oryzias latipes).
    Cheng N; Guo M; Chang P; Zhang X; Zhang R; Qi C; Zhong X; Zhou Q; Zhao H
    Fish Physiol Biochem; 2016 Jun; 42(3):1053-61. PubMed ID: 26749004
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.
    Wei TY; Hsia JY; Chiu SC; Su LJ; Juan CC; Lee YC; Chen JM; Chou HY; Huang JY; Huang HM; Yu CT
    Cell Signal; 2014 Dec; 26(12):2940-50. PubMed ID: 25277535
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.
    Ho MC; Wilczek C; Bonanno JB; Xing L; Seznec J; Matsui T; Carter LG; Onikubo T; Kumar PR; Chan MK; Brenowitz M; Cheng RH; Reimer U; Almo SC; Shechter D
    PLoS One; 2013; 8(2):e57008. PubMed ID: 23451136
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases.
    Jain K; Jin CY; Clarke SG
    Proc Natl Acad Sci U S A; 2017 Sep; 114(38):10101-10106. PubMed ID: 28874563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5.
    Fulton MD; Dang T; Brown T; Zheng YG
    Epigenetics; 2022 Jan; 17(1):1-18. PubMed ID: 33380261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the Kinetic Mechanism of Human Protein Arginine Methyltransferase 5.
    Eddershaw AR; Stubbs CJ; Edwardes LV; Underwood E; Hamm GR; Davey PRJ; Clarkson PN; Syson K
    Biochemistry; 2020 Dec; 59(50):4775-4786. PubMed ID: 33274632
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex.
    Abe Y; Suzuki Y; Kawamura K; Tanaka N
    Commun Biol; 2019; 2():23. PubMed ID: 30675521
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.