425 related articles for article (PubMed ID: 25486199)
1. Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.
Caruso JA; Campana R; Wei C; Su CH; Hanks AM; Bornmann WG; Keyomarsi K
Cell Cycle; 2014; 13(16):2587-99. PubMed ID: 25486199
[TBL] [Abstract][Full Text] [Related]
2. Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop.
Marconett CN; Sundar SN; Poindexter KM; Stueve TR; Bjeldanes LF; Firestone GL
Mol Biol Cell; 2010 Apr; 21(7):1166-77. PubMed ID: 20130088
[TBL] [Abstract][Full Text] [Related]
3. Estrogen receptor α and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells.
Brinkman AM; Wu J; Ersland K; Xu W
BMC Cancer; 2014 May; 14():344. PubMed ID: 24885022
[TBL] [Abstract][Full Text] [Related]
4. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
Aronchik I; Chen T; Durkin KA; Horwitz MS; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Mol Carcinog; 2012 Nov; 51(11):881-94. PubMed ID: 22012859
[TBL] [Abstract][Full Text] [Related]
5. The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing.
Nguyen HH; Aronchik I; Brar GA; Nguyen DH; Bjeldanes LF; Firestone GL
Proc Natl Acad Sci U S A; 2008 Dec; 105(50):19750-5. PubMed ID: 19064917
[TBL] [Abstract][Full Text] [Related]
6. 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
Nguyen HH; Lavrenov SN; Sundar SN; Nguyen DH; Tseng M; Marconett CN; Kung J; Staub RE; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Chem Biol Interact; 2010 Aug; 186(3):255-66. PubMed ID: 20570586
[TBL] [Abstract][Full Text] [Related]
7. Low levels of 3,3'-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol.
Marques M; Laflamme L; Benassou I; Cissokho C; Guillemette B; Gaudreau L
BMC Cancer; 2014 Jul; 14():524. PubMed ID: 25048790
[TBL] [Abstract][Full Text] [Related]
8. N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
Jump SM; Kung J; Staub R; Kinseth MA; Cram EJ; Yudina LN; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Biochem Pharmacol; 2008 Feb; 75(3):713-24. PubMed ID: 18023427
[TBL] [Abstract][Full Text] [Related]
9. Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells.
Sundar SN; Kerekatte V; Equinozio CN; Doan VB; Bjeldanes LF; Firestone GL
Mol Endocrinol; 2006 Dec; 20(12):3070-82. PubMed ID: 16901971
[TBL] [Abstract][Full Text] [Related]
10. Indole-3-carbinol induces tumor cell death: function follows form.
Megna BW; Carney PR; Nukaya M; Geiger P; Kennedy GD
J Surg Res; 2016 Jul; 204(1):47-54. PubMed ID: 27451867
[TBL] [Abstract][Full Text] [Related]
11. Effects of analogs of indole-3-carbinol cyclic trimerization product in human breast cancer cells.
Xue L; Schaldach CM; Janosik T; Bergman J; Bjeldanes LF
Chem Biol Interact; 2005 Apr; 152(2-3):119-29. PubMed ID: 15840385
[TBL] [Abstract][Full Text] [Related]
12. The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.
De Santi M; Galluzzi L; Lucarini S; Paoletti MF; Fraternale A; Duranti A; De Marco C; Fanelli M; Zaffaroni N; Brandi G; Magnani M
Breast Cancer Res; 2011 Mar; 13(2):R33. PubMed ID: 21435243
[TBL] [Abstract][Full Text] [Related]
13. Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.
Marconett CN; Singhal AK; Sundar SN; Firestone GL
Mol Cell Endocrinol; 2012 Nov; 363(1-2):74-84. PubMed ID: 22835548
[TBL] [Abstract][Full Text] [Related]
14. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells.
Tin AS; Park AH; Sundar SN; Firestone GL
BMC Biol; 2014 Sep; 12():72. PubMed ID: 25209720
[TBL] [Abstract][Full Text] [Related]
15. Modulation of Estrogen α and Progesterone Receptors in Triple Negative Breast Cancer Cell Lines: The Effects of Vorinostat and Indole-3-Carbinol In Vitro.
Nouri Emamzadeh F; Word B; Cotton E; Hawkins A; Littlejohn K; Moore R; Miranda-Carbon G; Orish CN; Lyn-Cook B
Anticancer Res; 2020 Jul; 40(7):3669-3683. PubMed ID: 32620606
[TBL] [Abstract][Full Text] [Related]
16. A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
Brandi G; Paiardini M; Cervasi B; Fiorucci C; Filippone P; De Marco C; Zaffaroni N; Magnani M
Cancer Res; 2003 Jul; 63(14):4028-36. PubMed ID: 12874002
[TBL] [Abstract][Full Text] [Related]
17. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.
Cover CM; Hsieh SJ; Tran SH; Hallden G; Kim GS; Bjeldanes LF; Firestone GL
J Biol Chem; 1998 Feb; 273(7):3838-47. PubMed ID: 9461564
[TBL] [Abstract][Full Text] [Related]
18. Estrogen receptor alpha as a target for indole-3-carbinol.
Wang TT; Milner MJ; Milner JA; Kim YS
J Nutr Biochem; 2006 Oct; 17(10):659-64. PubMed ID: 16488130
[TBL] [Abstract][Full Text] [Related]
19. Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells.
Aronchik I; Bjeldanes LF; Firestone GL
Cancer Res; 2010 Jun; 70(12):4961-71. PubMed ID: 20530686
[TBL] [Abstract][Full Text] [Related]
20. Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
Marconett CN; Sundar SN; Tseng M; Tin AS; Tran KQ; Mahuron KM; Bjeldanes LF; Firestone GL
Carcinogenesis; 2011 Sep; 32(9):1315-23. PubMed ID: 21693539
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
