532 related articles for article (PubMed ID: 25486476)
1. The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.
Paternot S; Colleoni B; Bisteau X; Roger PP
Cell Cycle; 2014; 13(18):2879-88. PubMed ID: 25486476
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia.
Wang L; Wang J; Blaser BW; Duchemin AM; Kusewitt DF; Liu T; Caligiuri MA; Briesewitz R
Blood; 2007 Sep; 110(6):2075-83. PubMed ID: 17537993
[TBL] [Abstract][Full Text] [Related]
3. Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2.
Pack LR; Daigh LH; Chung M; Meyer T
Nat Commun; 2021 Jun; 12(1):3356. PubMed ID: 34099663
[TBL] [Abstract][Full Text] [Related]
4. Monoclonal antibodies to activated CDK4: use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27.
Coulonval K; Vercruysse V; Paternot S; Pita JM; Corman R; Raspé E; Roger PP
Cell Cycle; 2022 Jan; 21(1):12-32. PubMed ID: 34913830
[TBL] [Abstract][Full Text] [Related]
5. Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy.
Roberts PJ; Bisi JE; Strum JC; Combest AJ; Darr DB; Usary JE; Zamboni WC; Wong KK; Perou CM; Sharpless NE
J Natl Cancer Inst; 2012 Mar; 104(6):476-87. PubMed ID: 22302033
[TBL] [Abstract][Full Text] [Related]
6. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
Paternot S; Coulonval K; Dumont JE; Roger PP
J Biol Chem; 2003 Jul; 278(29):26533-40. PubMed ID: 12730225
[TBL] [Abstract][Full Text] [Related]
7. Distinct specificities of pRb phosphorylation by CDK4 activated by cyclin D1 or cyclin D3: differential involvement in the distinct mitogenic modes of thyroid epithelial cells.
Paternot S; Arsenijevic T; Coulonval K; Bockstaele L; Dumont JE; Roger PP
Cell Cycle; 2006 Jan; 5(1):61-70. PubMed ID: 16294008
[TBL] [Abstract][Full Text] [Related]
8. Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence.
Brookes S; Gagrica S; Sanij E; Rowe J; Gregory FJ; Hara E; Peters G
Cell Cycle; 2015; 14(8):1164-73. PubMed ID: 25695870
[TBL] [Abstract][Full Text] [Related]
9. The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway.
Cabrera MC; Díaz-Cruz ES; Kallakury BV; Pishvaian MJ; Grubbs CJ; Muccio DD; Furth PA
Cancer Prev Res (Phila); 2012 Jun; 5(6):810-21. PubMed ID: 22508966
[TBL] [Abstract][Full Text] [Related]
10. JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21.
Colleoni B; Paternot S; Pita JM; Bisteau X; Coulonval K; Davis RJ; Raspé E; Roger PP
Oncogene; 2017 Jul; 36(30):4349-4361. PubMed ID: 28368408
[TBL] [Abstract][Full Text] [Related]
11. Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.
Bockstaele L; Bisteau X; Paternot S; Roger PP
Mol Cell Biol; 2009 Aug; 29(15):4188-200. PubMed ID: 19487459
[TBL] [Abstract][Full Text] [Related]
12. p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells.
Cen L; Carlson BL; Schroeder MA; Ostrem JL; Kitange GJ; Mladek AC; Fink SR; Decker PA; Wu W; Kim JS; Waldman T; Jenkins RB; Sarkaria JN
Neuro Oncol; 2012 Jul; 14(7):870-81. PubMed ID: 22711607
[TBL] [Abstract][Full Text] [Related]
13. Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
Paternot S; Dumont JE; Roger PP
Mol Endocrinol; 2006 Dec; 20(12):3279-92. PubMed ID: 16916940
[TBL] [Abstract][Full Text] [Related]
14. Interaction of retinoblastoma protein and D cyclins during cell-growth inhibition by hexamethylenebisacetamide in TM2H mouse epithelial cells.
Said TK; Medina D
Mol Carcinog; 1998 Jun; 22(2):128-43. PubMed ID: 9655257
[TBL] [Abstract][Full Text] [Related]
15. Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells.
Wang D; Sun Y; Li W; Ye F; Zhang Y; Guo Y; Zhang DY; Suo J
Int J Mol Med; 2018 May; 41(5):2473-2484. PubMed ID: 29436583
[TBL] [Abstract][Full Text] [Related]
16. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Guiley KZ; Stevenson JW; Lou K; Barkovich KJ; Kumarasamy V; Wijeratne TU; Bunch KL; Tripathi S; Knudsen ES; Witkiewicz AK; Shokat KM; Rubin SM
Science; 2019 Dec; 366(6471):. PubMed ID: 31831640
[TBL] [Abstract][Full Text] [Related]
17. p27kip1 expression and phosphorylation dictate Palbociclib sensitivity in KRAS-mutated colorectal cancer.
Rampioni Vinciguerra GL; Dall'Acqua A; Segatto I; Mattevi MC; Russo F; Favero A; Cirombella R; Mungo G; Viotto D; Karimbayli J; Pesce M; Vecchione A; Belletti B; Baldassarre G
Cell Death Dis; 2021 Oct; 12(10):951. PubMed ID: 34654798
[TBL] [Abstract][Full Text] [Related]
18. Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".
Bockstaele L; Kooken H; Libert F; Paternot S; Dumont JE; de Launoit Y; Roger PP; Coulonval K
Mol Cell Biol; 2006 Jul; 26(13):5070-85. PubMed ID: 16782892
[TBL] [Abstract][Full Text] [Related]
19. Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.
Nemoto A; Saida S; Kato I; Kikuchi J; Furukawa Y; Maeda Y; Akahane K; Honna-Oshiro H; Goi K; Kagami K; Kimura S; Sato Y; Okabe S; Niwa A; Watanabe K; Nakahata T; Heike T; Sugita K; Inukai T
Mol Cancer Ther; 2016 Jan; 15(1):94-105. PubMed ID: 26637365
[TBL] [Abstract][Full Text] [Related]
20. The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis.
Coulonval K; Bockstaele L; Paternot S; Dumont JE; Roger PP
Exp Cell Res; 2003 Nov; 291(1):135-49. PubMed ID: 14597415
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]