BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 25489928)

  • 1. Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital.
    Schraplau A; Schewe B; Neuschäfer-Rube F; Ringel S; Neuber C; Kleuser B; Püschel GP
    Toxicology; 2015 Feb; 328():21-8. PubMed ID: 25489928
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
    Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines.
    Kubešová K; Dořičáková A; Trávníček Z; Dvořák Z
    Toxicol Lett; 2016 Jul; 255():24-35. PubMed ID: 27180721
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.
    Wieneke N; Neuschäfer-Rube F; Bode LM; Kuna M; Andres J; Carnevali LC; Hirsch-Ernst KI; Püschel GP
    Toxicol Appl Pharmacol; 2009 Oct; 240(1):99-107. PubMed ID: 19631232
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Octachlorostyrene induces cytochrome P450, UDP-glucuronosyltransferase, and sulfotransferase via the aryl hydrocarbon receptor and constitutive androstane receptor.
    Yanagiba Y; Ito Y; Kamijima M; Gonzalez FJ; Nakajima T
    Toxicol Sci; 2009 Sep; 111(1):19-26. PubMed ID: 19525444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes.
    Neuschäfer-Rube F; Schraplau A; Schewe B; Lieske S; Krützfeldt JM; Ringel S; Henkel J; Birkenfeld AL; Püschel GP
    Toxicology; 2015 Nov; 337():1-9. PubMed ID: 26303333
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1.
    Muangmoonchai R; Smirlis D; Wong SC; Edwards M; Phillips IR; Shephard EA
    Biochem J; 2001 Apr; 355(Pt 1):71-8. PubMed ID: 11256950
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L; Stanton JD; Tolson AH; Luo Y; Wang H
    Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes.
    Ooe H; Kon J; Oshima H; Mitaka T
    Drug Metab Dispos; 2009 Sep; 37(9):1963-9. PubMed ID: 19520777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke.
    Bing Y; Zhu S; Jiang K; Dong G; Li J; Yang Z; Yang J; Yue J
    Biochem Pharmacol; 2014 Feb; 87(4):636-49. PubMed ID: 24368200
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.
    Ganem LG; Trottier E; Anderson A; Jefcoate CR
    Toxicol Appl Pharmacol; 1999 Feb; 155(1):32-42. PubMed ID: 10036216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
    Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression.
    Vaas S; Kreft L; Schwarz M; Braeuning A
    Toxicology; 2014 Nov; 325():31-41. PubMed ID: 25174530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
    Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
    J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells.
    Goedtke L; Sprenger H; Hofmann U; Schmidt FF; Hammer HS; Zanger UM; Poetz O; Seidel A; Braeuning A; Hessel-Pras S
    Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33396476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver.
    Patel RD; Hollingshead BD; Omiecinski CJ; Perdew GH
    Hepatology; 2007 Jul; 46(1):209-18. PubMed ID: 17596880
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB; Klaassen CD
    Drug Metab Dispos; 2009 Apr; 37(4):847-56. PubMed ID: 19144771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism.
    Qatanani M; Zhang J; Moore DD
    Endocrinology; 2005 Mar; 146(3):995-1002. PubMed ID: 15564320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.
    Lahoti TS; Boyer JA; Kusnadi A; Muku GE; Murray IA; Perdew GH
    Toxicol Sci; 2015 Nov; 148(1):229-40. PubMed ID: 26259605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.