BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 25490417)

  • 1. Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.
    dʼUscio LV; Santhanam AV; Katusic ZS
    J Cardiovasc Pharmacol; 2014 Dec; 64(6):514-21. PubMed ID: 25490417
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.
    Santhanam AV; d'Uscio LV; Katusic ZS
    J Neurochem; 2014 Nov; 131(4):521-9. PubMed ID: 25041251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.
    d'Uscio LV; Smith LA; Katusic ZS
    Am J Physiol Heart Circ Physiol; 2011 Dec; 301(6):H2227-34. PubMed ID: 21963838
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
    Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
    J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
    Santhanam AV; d'Uscio LV; Katusic ZS
    Brain Res; 2015 Nov; 1625():198-205. PubMed ID: 26343845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
    Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
    Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
    Sugiyama T; Levy BD; Michel T
    J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene.
    d'Uscio LV; He T; Santhanam AV; Tai LJ; Evans RM; Katusic ZS
    Am J Physiol Heart Circ Physiol; 2014 Apr; 306(7):H1001-10. PubMed ID: 24486511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
    Santhanam AV; d'Uscio LV; He T; Das P; Younkin SG; Katusic ZS
    J Neurochem; 2015 Sep; 134(6):1129-38. PubMed ID: 26111938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.
    d'Uscio LV; Das P; Santhanam AV; He T; Younkin SG; Katusic ZS
    Cardiovasc Res; 2012 Dec; 96(3):504-12. PubMed ID: 22886847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
    Cai S; Khoo J; Channon KM
    Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
    Crabtree MJ; Tatham AL; Al-Wakeel Y; Warrick N; Hale AB; Cai S; Channon KM; Alp NJ
    J Biol Chem; 2009 Jan; 284(2):1136-44. PubMed ID: 19011239
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Augmentation of vascular remodeling by uncoupled endothelial nitric oxide synthase in a mouse model of diabetes mellitus.
    Sasaki N; Yamashita T; Takaya T; Shinohara M; Shiraki R; Takeda M; Emoto N; Fukatsu A; Hayashi T; Ikemoto K; Nomura T; Yokoyama M; Hirata K; Kawashima S
    Arterioscler Thromb Vasc Biol; 2008 Jun; 28(6):1068-76. PubMed ID: 18403727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
    Alp NJ; McAteer MA; Khoo J; Choudhury RP; Channon KM
    Arterioscler Thromb Vasc Biol; 2004 Mar; 24(3):445-50. PubMed ID: 14707037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Erythropoietin increases endothelial biosynthesis of tetrahydrobiopterin by activation of protein kinase B alpha/Akt1.
    d'Uscio LV; Katusic ZS
    Hypertension; 2008 Jul; 52(1):93-9. PubMed ID: 18519842
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Supplement of tetrahydrobiopterin by a gene transfer of GTP cyclohydrolase I cDNA improves vascular dysfunction in insulin-resistant rats.
    Shinozaki K; Nishio Y; Yoshida Y; Koya D; Ayajiki K; Masada M; Kashiwagi A; Okamura T
    J Cardiovasc Pharmacol; 2005 Oct; 46(4):505-12. PubMed ID: 16160605
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
    Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
    Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
    Chuaiphichai S; McNeill E; Douglas G; Crabtree MJ; Bendall JK; Hale AB; Alp NJ; Channon KM
    Hypertension; 2014 Sep; 64(3):530-40. PubMed ID: 24777984
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells.
    Zhu M; Chen J; Tan Z; Wang J
    Anesth Analg; 2012 Feb; 114(2):303-9. PubMed ID: 22156331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
    Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
    Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.