BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 25499217)

  • 1. Regulation of Mcl-1 expression in context to bone marrow stromal microenvironment in chronic lymphocytic leukemia.
    Balakrishnan K; Burger JA; Fu M; Doifode T; Wierda WG; Gandhi V
    Neoplasia; 2014 Dec; 16(12):1036-46. PubMed ID: 25499217
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways.
    Amigo-Jiménez I; Bailón E; Aguilera-Montilla N; Terol MJ; García-Marco JA; García-Pardo A
    Oncotarget; 2015 Dec; 6(42):44832-48. PubMed ID: 26540567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
    Steele AJ; Prentice AG; Cwynarski K; Hoffbrand AV; Hart SM; Lowdell MW; Samuel ER; Wickremasinghe RG
    Blood; 2010 Nov; 116(22):4569-77. PubMed ID: 20716767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia.
    Sivina M; Hartmann E; Vasyutina E; Boucas JM; Breuer A; Keating MJ; Wierda WG; Rosenwald A; Herling M; Burger JA
    Leukemia; 2012 Aug; 26(8):1812-20. PubMed ID: 22460735
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
    Chen R; Guo L; Chen Y; Jiang Y; Wierda WG; Plunkett W
    Blood; 2011 Jan; 117(1):156-64. PubMed ID: 20971952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia.
    van Attekum MHA; Terpstra S; Slinger E; von Lindern M; Moerland PD; Jongejan A; Kater AP; Eldering E
    Oncogene; 2017 Jun; 36(26):3651-3660. PubMed ID: 28192408
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.
    Longo PG; Laurenti L; Gobessi S; Sica S; Leone G; Efremov DG
    Blood; 2008 Jan; 111(2):846-55. PubMed ID: 17928528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells.
    Gobessi S; Laurenti L; Longo PG; Carsetti L; Berno V; Sica S; Leone G; Efremov DG
    Leukemia; 2009 Apr; 23(4):686-97. PubMed ID: 19092849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
    Balakrishnan K; Burger JA; Quiroga MP; Henneberg M; Ayres ML; Wierda WG; Gandhi V
    Blood; 2010 Aug; 116(7):1083-91. PubMed ID: 20442367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications.
    Crompot E; Van Damme M; Pieters K; Vermeersch M; Perez-Morga D; Mineur P; Maerevoet M; Meuleman N; Bron D; Lagneaux L; Stamatopoulos B
    Haematologica; 2017 Sep; 102(9):1594-1604. PubMed ID: 28596280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chronic lymphocytic leukemia cells induce anti-apoptotic effects of bone marrow stroma.
    Plander M; Ugocsai P; Seegers S; Orsó E; Reichle A; Schmitz G; Hofstädter F; Brockhoff G
    Ann Hematol; 2011 Dec; 90(12):1381-90. PubMed ID: 21465189
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.
    Balakrishnan K; Burger JA; Wierda WG; Gandhi V
    Blood; 2009 Jan; 113(1):149-53. PubMed ID: 18836097
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bryostatin induces protein kinase C modulation, Mcl-1 up-regulation and phosphorylation of Bcl-2 resulting in cellular differentiation and resistance to drug-induced apoptosis in B-cell chronic lymphocytic leukemia cells.
    Thomas A; Pepper C; Hoy T; Bentley P
    Leuk Lymphoma; 2004 May; 45(5):997-1008. PubMed ID: 15291360
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia.
    Johnston JB; Paul JT; Neufeld NJ; Haney N; Kropp DM; Hu X; Cheang M; Gibson SB
    Leuk Lymphoma; 2004 Oct; 45(10):2017-27. PubMed ID: 15370246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6.
    Lu K; Fang XS; Feng LL; Jiang YJ; Zhou XX; Liu X; Li PP; Chen N; Ding M; Wang N; Zhang J; Wang X
    Cancer Lett; 2015 Apr; 359(2):250-8. PubMed ID: 25636517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells.
    Allen JC; Talab F; Zuzel M; Lin K; Slupsky JR
    Blood; 2011 Feb; 117(8):2414-22. PubMed ID: 21220745
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.
    Baudot AD; Jeandel PY; Mouska X; Maurer U; Tartare-Deckert S; Raynaud SD; Cassuto JP; Ticchioni M; Deckert M
    Oncogene; 2009 Sep; 28(37):3261-73. PubMed ID: 19581935
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of Cx43 gene-modified leukemic bone marrow stromal cells on the regulation of Jurkat cell line in vitro.
    Zhang X; Liu Y; Si YJ; Chen XH; Li ZJ; Gao L; Gao L; Zhang C
    Leuk Res; 2012 Feb; 36(2):198-204. PubMed ID: 22030334
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of NF-κB-mediated signaling by the cyclin-dependent kinase inhibitor CR8 overcomes prosurvival stimuli to induce apoptosis in chronic lymphocytic leukemia cells.
    Cosimo E; McCaig AM; Carter-Brzezinski LJ; Wheadon H; Leach MT; Le Ster K; Berthou C; Durieu E; Oumata N; Galons H; Meijer L; Michie AM
    Clin Cancer Res; 2013 May; 19(9):2393-405. PubMed ID: 23532892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).
    Fecteau JF; Bharati IS; O'Hayre M; Handel TM; Kipps TJ; Messmer D
    Mol Med; 2012 Feb; 18(1):19-28. PubMed ID: 21979753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.