These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

458 related articles for article (PubMed ID: 25500539)

  • 1. Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
    Azoulay-Alfaguter I; Elya R; Avrahami L; Katz A; Eldar-Finkelman H
    Oncogene; 2015 Aug; 34(35):4613-23. PubMed ID: 25500539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways.
    Avrahami L; Paz R; Dominko K; Hecimovic S; Bucci C; Eldar-Finkelman H
    Cell Signal; 2020 Jul; 71():109597. PubMed ID: 32173369
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies.
    Avrahami L; Farfara D; Shaham-Kol M; Vassar R; Frenkel D; Eldar-Finkelman H
    J Biol Chem; 2013 Jan; 288(2):1295-306. PubMed ID: 23155049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners.
    Ying Z; Xia Q; Hao Z; Xu D; Wang M; Wang H; Wang G
    Autophagy; 2016; 12(4):707-8. PubMed ID: 27050460
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells.
    Sokolosky M; Chappell WH; Stadelman K; Abrams SL; Davis NM; Steelman LS; McCubrey JA
    Cell Cycle; 2014; 13(5):820-33. PubMed ID: 24407515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration.
    Takayama K; Muto A; Kikuchi Y
    Sci Rep; 2018 May; 8(1):8278. PubMed ID: 29844341
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.
    Metz P; Chiramel A; Chatel-Chaix L; Alvisi G; Bankhead P; Mora-Rodriguez R; Long G; Hamacher-Brady A; Brady NR; Bartenschlager R
    J Virol; 2015 Aug; 89(15):8026-41. PubMed ID: 26018155
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysosomes: Regulators of autophagy in the retinal pigmented epithelium.
    Sinha D; Valapala M; Shang P; Hose S; Grebe R; Lutty GA; Zigler JS; Kaarniranta K; Handa JT
    Exp Eye Res; 2016 Mar; 144():46-53. PubMed ID: 26321509
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.
    Hwang JY; Gertner M; Pontarelli F; Court-Vazquez B; Bennett MV; Ofengeim D; Zukin RS
    Cell Death Differ; 2017 Feb; 24(2):317-329. PubMed ID: 27935582
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of Autophagy by the Glycogen Synthase Kinase-3 (GSK-3) Signaling Pathway.
    Pan HY; Valapala M
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
    Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
    PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTOR complex 1 activity is required to maintain the canonical endocytic recycling pathway against lysosomal delivery.
    Dauner K; Eid W; Raghupathy R; Presley JF; Zha X
    J Biol Chem; 2017 Apr; 292(14):5737-5747. PubMed ID: 28196862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lysosomal pH Plays a Key Role in Regulation of mTOR Activity in Osteoclasts.
    Hu Y; Carraro-Lacroix LR; Wang A; Owen C; Bajenova E; Corey PN; Brumell JH; Voronov I
    J Cell Biochem; 2016 Feb; 117(2):413-25. PubMed ID: 26212375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis.
    Saiprasad G; Chitra P; Manikandan R; Sudhandiran G
    Eur J Cancer; 2014 Sep; 50(14):2489-507. PubMed ID: 25047426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual suppressive effect of MTORC1 on autophagy: tame the dragon by shackling both the head and the tail.
    Zhou J; Tan SH; Codogno P; Shen HM
    Autophagy; 2013 May; 9(5):803-5. PubMed ID: 23439250
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mammalian target of rapamycin and tuberous sclerosis complex.
    Wataya-Kaneda M
    J Dermatol Sci; 2015 Aug; 79(2):93-100. PubMed ID: 26051878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.
    Bartolomeo R; Cinque L; De Leonibus C; Forrester A; Salzano AC; Monfregola J; De Gennaro E; Nusco E; Azario I; Lanzara C; Serafini M; Levine B; Ballabio A; Settembre C
    J Clin Invest; 2017 Oct; 127(10):3717-3729. PubMed ID: 28872463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.
    Rui YN; Xu Z; Chen Z; Zhang S
    Autophagy; 2015; 11(5):812-32. PubMed ID: 25984893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
    Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS
    Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis.
    Nakadera E; Yamashina S; Izumi K; Inami Y; Sato T; Fukushima H; Kon K; Ikejima K; Ueno T; Watanabe S
    Biochem Biophys Res Commun; 2016 Jan; 469(4):1104-10. PubMed ID: 26687947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.