274 related articles for article (PubMed ID: 25501874)
1. Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans.
Xu XH; Huang XW; Qun L; Li YN; Wang Y; Liu C; Ma Y; Liu QM; Sun K; Qian F; Jin L; Wang J
Sci Rep; 2014 Dec; 4():7465. PubMed ID: 25501874
[TBL] [Abstract][Full Text] [Related]
2. Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
Peng Y; Cui C; He Y; Ouzhuluobu ; Zhang H; Yang D; Zhang Q; Bianbazhuoma ; Yang L; He Y; Xiang K; Zhang X; Bhandari S; Shi P; Yangla ; Dejiquzong ; Baimakangzhuo ; Duojizhuoma ; Pan Y; Cirenyangji ; Baimayangji ; Gonggalanzi ; Bai C; Bianba ; Basang ; Ciwangsangbu ; Xu S; Chen H; Liu S; Wu T; Qi X; Su B
Mol Biol Evol; 2017 Apr; 34(4):818-830. PubMed ID: 28096303
[TBL] [Abstract][Full Text] [Related]
3. Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.
Hanaoka M; Droma Y; Basnyat B; Ito M; Kobayashi N; Katsuyama Y; Kubo K; Ota M
PLoS One; 2012; 7(12):e50566. PubMed ID: 23227185
[TBL] [Abstract][Full Text] [Related]
4. An EPAS1 haplotype is associated with high altitude polycythemia in male Han Chinese at the Qinghai-Tibetan plateau.
Chen Y; Jiang C; Luo Y; Liu F; Gao Y
Wilderness Environ Med; 2014 Dec; 25(4):392-400. PubMed ID: 25239027
[TBL] [Abstract][Full Text] [Related]
5. EPAS1 Gene Polymorphisms Are Associated With High Altitude Polycythemia in Tibetans at the Qinghai-Tibetan Plateau.
Xu J; Yang YZ; Tang F; Ga Q; Tana W; Ge RL
Wilderness Environ Med; 2015 Sep; 26(3):288-94. PubMed ID: 25792003
[TBL] [Abstract][Full Text] [Related]
6. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders.
Tashi T; Scott Reading N; Wuren T; Zhang X; Moore LG; Hu H; Tang F; Shestakova A; Lorenzo F; Burjanivova T; Koul P; Guchhait P; Wittwer CT; Julian CG; Shah B; Huff CD; Gordeuk VR; Prchal JT; Ge R
J Mol Med (Berl); 2017 Jun; 95(6):665-670. PubMed ID: 28233034
[TBL] [Abstract][Full Text] [Related]
7. HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans.
Yang D; Peng Y; Ouzhuluobu ; Bianbazhuoma ; Cui C; Bianba ; Wang L; Xiang K; He Y; Zhang H; Zhang X; Liu J; Shi H; Pan Y; Duojizhuoma ; Dejiquzong ; Cirenyangji ; Baimakangzhuo ; Gonggalanzi ; Liu S; Gengdeng ; Wu T; Chen H; Qi X; Su B
Hum Mutat; 2016 Feb; 37(2):216-23. PubMed ID: 26781569
[TBL] [Abstract][Full Text] [Related]
8. Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.
Schweizer RM; Velotta JP; Ivy CM; Jones MR; Muir SM; Bradburd GS; Storz JF; Scott GR; Cheviron ZA
PLoS Genet; 2019 Nov; 15(11):e1008420. PubMed ID: 31697676
[TBL] [Abstract][Full Text] [Related]
9. Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans.
Simonson TS; Huff CD; Witherspoon DJ; Prchal JT; Jorde LB
Exp Physiol; 2015 Nov; 100(11):1263-8. PubMed ID: 26454145
[TBL] [Abstract][Full Text] [Related]
10. Evolutionary history of Tibetans inferred from whole-genome sequencing.
Hu H; Petousi N; Glusman G; Yu Y; Bohlender R; Tashi T; Downie JM; Roach JC; Cole AM; Lorenzo FR; Rogers AR; Brunkow ME; Cavalleri G; Hood L; Alpatty SM; Prchal JT; Jorde LB; Robbins PA; Simonson TS; Huff CD
PLoS Genet; 2017 Apr; 13(4):e1006675. PubMed ID: 28448578
[TBL] [Abstract][Full Text] [Related]
11. Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia.
Petousi N; Croft QP; Cavalleri GL; Cheng HY; Formenti F; Ishida K; Lunn D; McCormack M; Shianna KV; Talbot NP; Ratcliffe PJ; Robbins PA
J Appl Physiol (1985); 2014 Apr; 116(7):893-904. PubMed ID: 24030663
[TBL] [Abstract][Full Text] [Related]
12. Genetic determinants of Tibetan high-altitude adaptation.
Simonson TS; McClain DA; Jorde LB; Prchal JT
Hum Genet; 2012 Apr; 131(4):527-33. PubMed ID: 22068265
[TBL] [Abstract][Full Text] [Related]
13. Mutations in EPAS1 in congenital heart disease in Tibetans.
Pan H; Chen Q; Qi S; Li T; Liu B; Liu S; Ma X; Wang B
Biosci Rep; 2018 Dec; 38(6):. PubMed ID: 30487161
[No Abstract] [Full Text] [Related]
14. A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence.
Lou H; Lu Y; Lu D; Fu R; Wang X; Feng Q; Wu S; Yang Y; Li S; Kang L; Guan Y; Hoh BP; Chung YJ; Jin L; Su B; Xu S
Am J Hum Genet; 2015 Jul; 97(1):54-66. PubMed ID: 26073780
[TBL] [Abstract][Full Text] [Related]
15. Differentiation analysis for estimating individual ancestry from the Tibetan Plateau by an archaic altitude adaptation EPAS1 haplotype among East Asian populations.
Jiang L; Peng J; Huang M; Liu J; Wang L; Ma Q; Zhao H; Yang X; Ji A; Li C
Int J Legal Med; 2018 Nov; 132(6):1527-1535. PubMed ID: 29428968
[TBL] [Abstract][Full Text] [Related]
16. [Association between polymorphisms of HIF-1alpha C1772T and G1790A and hypoxic acclimation in high altitude in Tibetans].
Liu K; Sun X; Wang S; Hu B
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2007 Jun; 24(3):654-8. PubMed ID: 17713282
[TBL] [Abstract][Full Text] [Related]
17. A non-synonymous SNP with the allele frequency correlated with the altitude may contribute to the hypoxia adaptation of Tibetan chicken.
Li S; Li D; Zhao X; Wang Y; Yin H; Zhou L; Zhong C; Zhu Q
PLoS One; 2017; 12(2):e0172211. PubMed ID: 28222154
[TBL] [Abstract][Full Text] [Related]
18. MBD3 mediates epigenetic regulation on EPAS1 promoter in cancer.
Cui J; Duan B; Zhao X; Chen Y; Sun S; Deng W; Zhang Y; Du J; Chen Y; Gu L
Tumour Biol; 2016 Oct; 37(10):13455-13467. PubMed ID: 27465550
[TBL] [Abstract][Full Text] [Related]
19. Novel insight into the genetic signatures of altitude adaptation related body composition in Tibetans.
Li X; Xu S; Li X; Wang Y; Sheng Y; Zhang H; Yang W; Yuan D; Jin T; He X
Front Public Health; 2024; 12():1355659. PubMed ID: 38807991
[TBL] [Abstract][Full Text] [Related]
20. Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA.
Huerta-Sánchez E; Jin X; Asan ; Bianba Z; Peter BM; Vinckenbosch N; Liang Y; Yi X; He M; Somel M; Ni P; Wang B; Ou X; Huasang ; Luosang J; Cuo ZX; Li K; Gao G; Yin Y; Wang W; Zhang X; Xu X; Yang H; Li Y; Wang J; Wang J; Nielsen R
Nature; 2014 Aug; 512(7513):194-7. PubMed ID: 25043035
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
