These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 25503928)

  • 1. Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis.
    Hammer SC; Marjanovic A; Dominicus JM; Nestl BM; Hauer B
    Nat Chem Biol; 2015 Feb; 11(2):121-6. PubMed ID: 25503928
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-directed mutagenesis of squalene-hopene cyclase: altered substrate specificity and product distribution.
    Dang T; Prestwich GD
    Chem Biol; 2000 Aug; 7(8):643-9. PubMed ID: 11048954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Squalene hopene cyclases: highly promiscuous and evolvable catalysts for stereoselective CC and CX bond formation.
    Hammer SC; Syrén PO; Seitz M; Nestl BM; Hauer B
    Curr Opin Chem Biol; 2013 Apr; 17(2):293-300. PubMed ID: 23485581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alicyclobacillus acidocaldarius Squalene-Hopene Cyclase: The Critical Role of Steric Bulk at Ala306 and the First Enzymatic Synthesis of Epoxydammarane from 2,3-Oxidosqualene.
    Ideno N; Umeyama S; Watanabe T; Nakajima M; Sato T; Hoshino T
    Chembiochem; 2018 Sep; 19(17):1873-1886. PubMed ID: 29911308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring.
    Hoshino T; Nakano S; Kondo T; Sato T; Miyoshi A
    Org Biomol Chem; 2004 May; 2(10):1456-70. PubMed ID: 15136801
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reviewing the polyolefin cyclization reaction of the c(35) polyprene catalyzed by squalene-hopene cyclase.
    Hoshino T; Kumai Y; Sato T
    Chemistry; 2009; 15(9):2091-100. PubMed ID: 19142932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange.
    Siedenburg G; Breuer M; Jendrossek D
    Appl Microbiol Biotechnol; 2013 Feb; 97(4):1571-80. PubMed ID: 22526778
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Squalene-hopene cyclases-evolution, dynamics and catalytic scope.
    Syrén PO; Henche S; Eichler A; Nestl BM; Hauer B
    Curr Opin Struct Biol; 2016 Dec; 41():73-82. PubMed ID: 27336183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conversion of squalene to the pentacarbocyclic hopene.
    Reinert DJ; Balliano G; Schulz GE
    Chem Biol; 2004 Jan; 11(1):121-6. PubMed ID: 15113001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius.
    Sato T; Kouda M; Hoshino T
    Biosci Biotechnol Biochem; 2004 Mar; 68(3):728-38. PubMed ID: 15056909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzymatic Addition of Alcohols to Terpenes by Squalene Hopene Cyclase Variants.
    Kühnel LC; Nestl BM; Hauer B
    Chembiochem; 2017 Nov; 18(22):2222-2225. PubMed ID: 28898524
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase: a chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships.
    Wu TK; Chang CH; Liu YT; Wang TT
    Chem Rec; 2008; 8(5):302-25. PubMed ID: 18956480
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Profound insights into squalene cyclization.
    Poralla K
    Chem Biol; 2004 Jan; 11(1):12-4. PubMed ID: 15112988
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deletion of the Gly600 residue of Alicyclobacillus acidocaldarius squalene cyclase alters the substrate specificity into that of the eukaryotic-type cyclase specific to (3S)-2,3-oxidosqualene.
    Hoshino T; Shimizu K; Sato T
    Angew Chem Int Ed Engl; 2004 Dec; 43(48):6700-3. PubMed ID: 15593147
    [No Abstract]   [Full Text] [Related]  

  • 15. Chemo-enzymatic syntheses of drimane-type sesquiterpenes and the fundamental core of hongoquercin meroterpenoid by recombinant squalene-hopene cyclase.
    Yonemura Y; Ohyama T; Hoshino T
    Org Biomol Chem; 2012 Jan; 10(2):440-6. PubMed ID: 22068606
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Squalene-hopene cyclase: insight into the role of the methyl group on the squalene backbone upon the polycyclization cascade. Enzymatic cyclization products of squalene analogs lacking a 26-methyl group and possessing a methyl group at C7 or C11.
    Nakano S; Ohashi S; Hoshino T
    Org Biomol Chem; 2004 Jul; 2(14):2012-22. PubMed ID: 15254628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Concerted nature of AB ring formation in the enzymatic cyclization of squalene to hopenes.
    Hess BA; Smentek L
    Org Lett; 2004 May; 6(11):1717-20. PubMed ID: 15151397
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanistic insights into oxidosqualene cyclizations through homology modeling.
    Schulz-Gasch T; Stahl M
    J Comput Chem; 2003 Apr; 24(6):741-53. PubMed ID: 12666166
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Site-directed mutagenesis of putative active-site residues in squalene-hopene cyclase.
    Feil C; Süssmuth R; Jung G; Poralla K
    Eur J Biochem; 1996 Nov; 242(1):51-5. PubMed ID: 8954152
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New cyclization mechanism for squalene: a ring-expansion step for the five-membered C-ring intermediate in hopene biosynthesis.
    Hoshino T; Kouda M; Abe T; Ohashi S
    Biosci Biotechnol Biochem; 1999 Nov; 63(11):2038-41. PubMed ID: 10635573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.