BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 25509983)

  • 1. Anticancer activity of pristimerin in ovarian carcinoma cells is mediated through the inhibition of prosurvival Akt/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Gautam SC
    J Exp Ther Oncol; 2014; 10(4):275-83. PubMed ID: 25509983
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2.
    Deeb D; Gao X; Liu YB; Pindolia K; Gautam SC
    Int J Oncol; 2014 May; 44(5):1707-15. PubMed ID: 24603988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
    Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling.
    Deeb D; Gao X; Liu Y; Zhang Y; Shaw J; Valeriote FA; Gautam SC
    Int J Oncol; 2016 Sep; 49(3):1139-47. PubMed ID: 27573873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.
    Liu Y; Gao X; Deeb D; Zhang Y; Shaw J; Valeriote FA; Gautam SC
    J Exp Ther Oncol; 2016 Nov; 11(4):251-260. PubMed ID: 27849335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Gao X; Liu Y; Deeb D; Liu P; Liu A; Arbab AS; Gautam SC
    Anticancer Res; 2013 Jan; 33(1):215-21. PubMed ID: 23267148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-κB signaling or PI3K/AKT/mTOR pathway.
    Zhang S; Leng T; Zhang Q; Zhao Q; Nie X; Yang L
    Biomed Pharmacother; 2018 Jun; 102():302-308. PubMed ID: 29571014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells.
    Rao YK; Wu AT; Geethangili M; Huang MT; Chao WJ; Wu CH; Deng WP; Yeh CT; Tzeng YM
    Chem Res Toxicol; 2011 Feb; 24(2):238-45. PubMed ID: 21158420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X; Deeb D; Jiang H; Liu Y; Dulchavsky SA; Gautam SC
    J Neurooncol; 2007 Sep; 84(2):147-57. PubMed ID: 17361329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
    Gao X; Deeb D; Hao J; Liu Y; Arbab AS; Dulchavsky SA; Gautam SC
    Anticancer Res; 2010 Mar; 30(3):785-92. PubMed ID: 20392997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Betulin terpenoid targets OVCAR-3 human ovarian carcinoma cells by inducing mitochondrial mediated apoptosis, G2/M phase cell cycle arrest, inhibition of cell migration and invasion and modulating mTOR/PI3K/AKT signalling pathway.
    Yang Q; Fei Z; Huang C
    Cell Mol Biol (Noisy-le-grand); 2021 Sep; 67(2):14-19. PubMed ID: 34817343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    Anticancer Res; 2007; 27(5A):3035-44. PubMed ID: 17970042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-proliferative effect of RCE-4 from Reineckia carnea on human cervical cancer HeLa cells by inhibiting the PI3K/Akt/mTOR signaling pathway and NF-κB activation.
    Bai C; Yang X; Zou K; He H; Wang J; Qin H; Yu X; Liu C; Zheng J; Cheng F; Chen J
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun; 389(6):573-84. PubMed ID: 26935715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway.
    Deeb D; Jiang H; Gao X; Al-Holou S; Danyluk AL; Dulchavsky SA; Gautam SC
    J Pharmacol Exp Ther; 2007 May; 321(2):616-25. PubMed ID: 17289836
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asiatic acid exerts anticancer potential in human ovarian cancer cells via suppression of PI3K/Akt/mTOR signalling.
    Ren L; Cao QX; Zhai FR; Yang SQ; Zhang HX
    Pharm Biol; 2016 Nov; 54(11):2377-2382. PubMed ID: 26984021
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alkaloids from Stephania venosa as Chemo-Sensitizers in SKOV3 Ovarian Cancer Cells via Akt/NF-κB Signaling.
    Mon MT; Yodkeeree S; Punfa W; Pompimon W; Limtrakul P
    Chem Pharm Bull (Tokyo); 2018; 66(2):162-169. PubMed ID: 29386467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Indole-2-Carboxamide Derivative LG25 Inhibits Triple-Negative Breast Cancer Growth By Suppressing Akt/mTOR/NF-κB Signalling Pathway.
    Xu X; Rajamanickam V; Shu S; Liu Z; Yan T; He J; Liu Z; Guo G; Liang G; Wang Y
    Drug Des Devel Ther; 2019; 13():3539-3550. PubMed ID: 31631978
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.
    Li C; Liu VW; Chan DW; Yao KM; Ngan HY
    Int J Gynecol Cancer; 2012 Jan; 22(1):15-22. PubMed ID: 22080879
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121.
    Peng Y; Zhou Y; Cheng L; Hu D; Zhou X; Wang Z; Xie C; Zhou F
    Biochem Biophys Res Commun; 2015 Sep; 465(1):137-44. PubMed ID: 26235881
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.