BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

418 related articles for article (PubMed ID: 25512232)

  • 1. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening.
    Wang Z; Luo X; Anene-Nzelu C; Yu Y; Hong X; Singh NH; Xia L; Liu S; Yu H
    J Appl Toxicol; 2015 Aug; 35(8):909-17. PubMed ID: 25512232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.
    Xia L; Hong X; Sakban RB; Qu Y; Singh NH; McMillian M; Dallas S; Silva J; Sensenhauser C; Zhao S; Lim HK; Yu H
    J Appl Toxicol; 2016 Feb; 36(2):320-9. PubMed ID: 26201057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tethered spheroids as an in vitro hepatocyte model for drug safety screening.
    Xia L; Sakban RB; Qu Y; Hong X; Zhang W; Nugraha B; Tong WH; Ananthanarayanan A; Zheng B; Chau IY; Jia R; McMillian M; Silva J; Dallas S; Yu H
    Biomaterials; 2012 Mar; 33(7):2165-76. PubMed ID: 22189144
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.
    Rebelo SP; Costa R; Estrada M; Shevchenko V; Brito C; Alves PM
    Arch Toxicol; 2015 Aug; 89(8):1347-58. PubMed ID: 25107451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells.
    Anthérieu S; Chesné C; Li R; Camus S; Lahoz A; Picazo L; Turpeinen M; Tolonen A; Uusitalo J; Guguen-Guillouzo C; Guillouzo A
    Drug Metab Dispos; 2010 Mar; 38(3):516-25. PubMed ID: 20019244
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies.
    Gunness P; Mueller D; Shevchenko V; Heinzle E; Ingelman-Sundberg M; Noor F
    Toxicol Sci; 2013 May; 133(1):67-78. PubMed ID: 23377618
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tethered primary hepatocyte spheroids on polystyrene multi-well plates for high-throughput drug safety testing.
    Tasnim F; Singh NH; Tan EKF; Xing J; Li H; Hissette S; Manesh S; Fulwood J; Gupta K; Ng CW; Xu S; Hill J; Yu H
    Sci Rep; 2020 Mar; 10(1):4768. PubMed ID: 32179810
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3D hepatocyte monolayer on hybrid RGD/galactose substratum.
    Du Y; Chia SM; Han R; Chang S; Tang H; Yu H
    Biomaterials; 2006 Nov; 27(33):5669-80. PubMed ID: 16904177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.
    Ramaiahgari SC; Waidyanatha S; Dixon D; DeVito MJ; Paules RS; Ferguson SS
    Toxicol Sci; 2017 Sep; 159(1):124-136. PubMed ID: 28633424
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
    Yokoyama Y; Sasaki Y; Terasaki N; Kawataki T; Takekawa K; Iwase Y; Shimizu T; Sanoh S; Ohta S
    Biol Pharm Bull; 2018 May; 41(5):722-732. PubMed ID: 29445054
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An Automated Multiplexed Hepatotoxicity and CYP Induction Assay Using HepaRG Cells in 2D and 3D.
    Ott LM; Ramachandran K; Stehno-Bittel L
    SLAS Discov; 2017 Jun; 22(5):614-625. PubMed ID: 28346810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.
    Lübberstedt M; Müller-Vieira U; Mayer M; Biemel KM; Knöspel F; Knobeloch D; Nüssler AK; Gerlach JC; Zeilinger K
    J Pharmacol Toxicol Methods; 2011; 63(1):59-68. PubMed ID: 20460162
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids.
    Shin DS; Seo H; Yang JY; Joo J; Im SH; Kim SS; Kim SK; Bae MA
    Int J Toxicol; 2018; 37(5):393-403. PubMed ID: 29923436
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies.
    Mueller D; Krämer L; Hoffmann E; Klein S; Noor F
    Toxicol In Vitro; 2014 Feb; 28(1):104-12. PubMed ID: 23850736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans.
    Kanebratt KP; Andersson TB
    Drug Metab Dispos; 2008 Jan; 36(1):137-45. PubMed ID: 17954527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates.
    Sanoh S; Santoh M; Takagi M; Kanayama T; Sugihara K; Kotake Y; Ejiri Y; Horie T; Kitamura S; Ohta S
    Toxicol In Vitro; 2014 Sep; 28(6):1176-82. PubMed ID: 24878114
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
    Bell CC; Dankers ACA; Lauschke VM; Sison-Young R; Jenkins R; Rowe C; Goldring CE; Park K; Regan SL; Walker T; Schofield C; Baze A; Foster AJ; Williams DP; van de Ven AWM; Jacobs F; Houdt JV; Lähteenmäki T; Snoeys J; Juhila S; Richert L; Ingelman-Sundberg M
    Toxicol Sci; 2018 Apr; 162(2):655-666. PubMed ID: 29329425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays.
    Murayama N; Usui T; Slawny N; Chesné C; Yamazaki H
    Drug Metab Lett; 2015; 9(1):3-7. PubMed ID: 25600204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells.
    Ogasawara A; Kato N; Torimoto N; Aohara F; Ohashi R; Yamada Y; Taniguchi H
    Drug Metab Lett; 2018; 12(1):14-23. PubMed ID: 29357810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
    Bell CC; Lauschke VM; Vorrink SU; Palmgren H; Duffin R; Andersson TB; Ingelman-Sundberg M
    Drug Metab Dispos; 2017 Apr; 45(4):419-429. PubMed ID: 28137721
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.