408 related articles for article (PubMed ID: 25512421)
1. Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.
Tanaka TQ; Guiguemde WA; Barnett DS; Maron MI; Min J; Connelly MC; Suryadevara PK; Guy RK; Williamson KC
Antimicrob Agents Chemother; 2015 Mar; 59(3):1389-97. PubMed ID: 25512421
[TBL] [Abstract][Full Text] [Related]
2. In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agents.
Patel PR; Sun W; Kim M; Huang X; Sanderson PE; Tanaka TQ; McKew JC; Simeonov A; Williamson KC; Zheng W; Huang W
Bioorg Med Chem Lett; 2016 Jun; 26(12):2907-2911. PubMed ID: 27156776
[TBL] [Abstract][Full Text] [Related]
3. Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screening.
Sun W; Huang X; Li H; Tawa G; Fisher E; Tanaka TQ; Shinn P; Huang W; Williamson KC; Zheng W
Malar J; 2017 Apr; 16(1):147. PubMed ID: 28407766
[TBL] [Abstract][Full Text] [Related]
4. Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
van der Watt ME; Reader J; Churchyard A; Nondaba SH; Lauterbach SB; Niemand J; Abayomi S; van Biljon RA; Connacher JI; van Wyk RDJ; Le Manach C; Paquet T; González Cabrera D; Brunschwig C; Theron A; Lozano-Arias S; Rodrigues JFI; Herreros E; Leroy D; Duffy J; Street LJ; Chibale K; Mancama D; Coetzer TL; Birkholtz LM
J Antimicrob Chemother; 2018 May; 73(5):1279-1290. PubMed ID: 29420756
[TBL] [Abstract][Full Text] [Related]
5. Maduramicin Rapidly Eliminates Malaria Parasites and Potentiates the Gametocytocidal Activity of the Pyrazoleamide PA21A050.
Maron MI; Magle CT; Czesny B; Turturice BA; Huang R; Zheng W; Vaidya AB; Williamson KC
Antimicrob Agents Chemother; 2015 Dec; 60(3):1492-9. PubMed ID: 26711768
[TBL] [Abstract][Full Text] [Related]
6. Aminonaphthoquinones--a novel class of compounds with potent antimalarial activity against Plasmodium falciparum.
Kapadia GJ; Azuine MA; Balasubramanian V; Sridhar R
Pharmacol Res; 2001 Apr; 43(4):363-7. PubMed ID: 11352541
[TBL] [Abstract][Full Text] [Related]
7. In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species.
Moyo P; Botha ME; Nondaba S; Niemand J; Maharaj VJ; Eloff JN; Louw AI; Birkholtz L
J Ethnopharmacol; 2016 Jun; 185():235-42. PubMed ID: 26994818
[TBL] [Abstract][Full Text] [Related]
8. Whole-cell in vitro screening for gametocytocidal compounds.
Lucantoni L; Avery V
Future Med Chem; 2012 Dec; 4(18):2337-60. PubMed ID: 23234555
[TBL] [Abstract][Full Text] [Related]
9. Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.
Reader J; Botha M; Theron A; Lauterbach SB; Rossouw C; Engelbrecht D; Wepener M; Smit A; Leroy D; Mancama D; Coetzer TL; Birkholtz LM
Malar J; 2015 May; 14():213. PubMed ID: 25994518
[TBL] [Abstract][Full Text] [Related]
10. Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Miguel-Blanco C; Molina I; Bardera AI; Díaz B; de Las Heras L; Lozano S; González C; Rodrigues J; Delves MJ; Ruecker A; Colmenarejo G; Viera S; Martínez-Martínez MS; Fernández E; Baum J; Sinden RE; Herreros E
Nat Commun; 2017 May; 8():15160. PubMed ID: 28513586
[TBL] [Abstract][Full Text] [Related]
11. Chemical signatures and new drug targets for gametocytocidal drug development.
Sun W; Tanaka TQ; Magle CT; Huang W; Southall N; Huang R; Dehdashti SJ; McKew JC; Williamson KC; Zheng W
Sci Rep; 2014 Jan; 4():3743. PubMed ID: 24434750
[TBL] [Abstract][Full Text] [Related]
12. Methylene blue induced morphological deformations in Plasmodium falciparum gametocytes: implications for transmission-blocking.
Wadi I; Pillai CR; Anvikar AR; Sinha A; Nath M; Valecha N
Malar J; 2018 Jan; 17(1):11. PubMed ID: 29310655
[TBL] [Abstract][Full Text] [Related]
13. Plasmodium falciparum gametocytes: with a view to a kill.
Butterworth AS; Skinner-Adams TS; Gardiner DL; Trenholme KR
Parasitology; 2013 Dec; 140(14):1718-34. PubMed ID: 23953486
[TBL] [Abstract][Full Text] [Related]
14. Effects of antimalarial molecules on the gametocyte stage of Plasmodium falciparum: the debate.
Dechy-Cabaret O; Benoit-Vical F
J Med Chem; 2012 Dec; 55(23):10328-44. PubMed ID: 23075290
[TBL] [Abstract][Full Text] [Related]
15. Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay.
Lucantoni L; Duffy S; Adjalley SH; Fidock DA; Avery VM
Antimicrob Agents Chemother; 2013 Dec; 57(12):6050-62. PubMed ID: 24060871
[TBL] [Abstract][Full Text] [Related]
16. Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.
Trenholme K; Marek L; Duffy S; Pradel G; Fisher G; Hansen FK; Skinner-Adams TS; Butterworth A; Ngwa CJ; Moecking J; Goodman CD; McFadden GI; Sumanadasa SD; Fairlie DP; Avery VM; Kurz T; Andrews KT
Antimicrob Agents Chemother; 2014 Jul; 58(7):3666-78. PubMed ID: 24733477
[TBL] [Abstract][Full Text] [Related]
17. A quantitative high throughput assay for identifying gametocytocidal compounds.
Tanaka TQ; Dehdashti SJ; Nguyen DT; McKew JC; Zheng W; Williamson KC
Mol Biochem Parasitol; 2013 Mar; 188(1):20-5. PubMed ID: 23454872
[TBL] [Abstract][Full Text] [Related]
18. Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites.
Dorjsuren D; Eastman RT; Wicht KJ; Jansen D; Talley DC; Sigmon BA; Zakharov AV; Roncal N; Girvin AT; Antonova-Koch Y; Will PM; Shah P; Sun H; Klumpp-Thomas C; Mok S; Yeo T; Meister S; Marugan JJ; Ross LS; Xu X; Maloney DJ; Jadhav A; Mott BT; Sciotti RJ; Winzeler EA; Waters NC; Campbell RF; Huang W; Simeonov A; Fidock DA
Sci Rep; 2021 Jan; 11(1):2121. PubMed ID: 33483532
[TBL] [Abstract][Full Text] [Related]
19. Progressing the global antimalarial portfolio: finding drugs which target multiple Plasmodium life stages.
Smith PW; Diagana TT; Yeung BK
Parasitology; 2014 Jan; 141(1):66-76. PubMed ID: 23746048
[TBL] [Abstract][Full Text] [Related]
20. Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes.
Lucantoni L; Fidock DA; Avery VM
Antimicrob Agents Chemother; 2016 Apr; 60(4):2097-107. PubMed ID: 26787698
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
