259 related articles for article (PubMed ID: 25512598)
1. Modulation of CFTR gating by permeant ions.
Yeh HI; Yeh JT; Hwang TC
J Gen Physiol; 2015 Jan; 145(1):47-60. PubMed ID: 25512598
[TBL] [Abstract][Full Text] [Related]
2. On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator.
Yu YC; Sohma Y; Hwang TC
J Physiol; 2016 Jun; 594(12):3227-44. PubMed ID: 26846474
[TBL] [Abstract][Full Text] [Related]
3. Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate.
Lin WY; Sohma Y; Hwang TC
Mol Pharmacol; 2016 Sep; 90(3):275-85. PubMed ID: 27413118
[TBL] [Abstract][Full Text] [Related]
4. A common mechanism for CFTR potentiators.
Yeh HI; Sohma Y; Conrath K; Hwang TC
J Gen Physiol; 2017 Dec; 149(12):1105-1118. PubMed ID: 29079713
[TBL] [Abstract][Full Text] [Related]
5. Vx-770 potentiates CFTR function by promoting decoupling between the gating cycle and ATP hydrolysis cycle.
Jih KY; Hwang TC
Proc Natl Acad Sci U S A; 2013 Mar; 110(11):4404-9. PubMed ID: 23440202
[TBL] [Abstract][Full Text] [Related]
6. The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics.
Zhou Z; Wang X; Liu HY; Zou X; Li M; Hwang TC
J Gen Physiol; 2006 Oct; 128(4):413-22. PubMed ID: 16966475
[TBL] [Abstract][Full Text] [Related]
7. G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects.
Bompadre SG; Sohma Y; Li M; Hwang TC
J Gen Physiol; 2007 Apr; 129(4):285-98. PubMed ID: 17353351
[TBL] [Abstract][Full Text] [Related]
8. Physiological and pharmacological characterization of the N1303K mutant CFTR.
DeStefano S; Gees M; Hwang TC
J Cyst Fibros; 2018 Sep; 17(5):573-581. PubMed ID: 29887518
[TBL] [Abstract][Full Text] [Related]
9. Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
Basso C; Vergani P; Nairn AC; Gadsby DC
J Gen Physiol; 2003 Sep; 122(3):333-48. PubMed ID: 12939393
[TBL] [Abstract][Full Text] [Related]
10. Structural mechanisms for defective CFTR gating caused by the Q1412X mutation, a severe Class VI pathogenic mutation in cystic fibrosis.
Yeh JT; Yu YC; Hwang TC
J Physiol; 2019 Jan; 597(2):543-560. PubMed ID: 30408177
[TBL] [Abstract][Full Text] [Related]
11. CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains.
Vergani P; Lockless SW; Nairn AC; Gadsby DC
Nature; 2005 Feb; 433(7028):876-80. PubMed ID: 15729345
[TBL] [Abstract][Full Text] [Related]
12. Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain.
Csanády L; Chan KW; Nairn AC; Gadsby DC
J Gen Physiol; 2005 Jan; 125(1):43-55. PubMed ID: 15596536
[TBL] [Abstract][Full Text] [Related]
13. Nonintegral stoichiometry in CFTR gating revealed by a pore-lining mutation.
Jih KY; Sohma Y; Hwang TC
J Gen Physiol; 2012 Oct; 140(4):347-59. PubMed ID: 22966014
[TBL] [Abstract][Full Text] [Related]
14. Potentiation of the cystic fibrosis transmembrane conductance regulator Cl
Wang Y; Cai Z; Gosling M; Sheppard DN
Am J Physiol Lung Cell Mol Physiol; 2018 Nov; 315(5):L846-L857. PubMed ID: 30136610
[TBL] [Abstract][Full Text] [Related]
15. Mechanism of G551D-CFTR (cystic fibrosis transmembrane conductance regulator) potentiation by a high affinity ATP analog.
Bompadre SG; Li M; Hwang TC
J Biol Chem; 2008 Feb; 283(9):5364-9. PubMed ID: 18167357
[TBL] [Abstract][Full Text] [Related]
16. Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.
Eckford PD; Li C; Ramjeesingh M; Bear CE
J Biol Chem; 2012 Oct; 287(44):36639-49. PubMed ID: 22942289
[TBL] [Abstract][Full Text] [Related]
17. State-dependent modulation of CFTR gating by pyrophosphate.
Tsai MF; Shimizu H; Sohma Y; Li M; Hwang TC
J Gen Physiol; 2009 Apr; 133(4):405-19. PubMed ID: 19332621
[TBL] [Abstract][Full Text] [Related]
18. Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle.
Csanády L; Nairn AC; Gadsby DC
J Gen Physiol; 2006 Nov; 128(5):523-33. PubMed ID: 17043148
[TBL] [Abstract][Full Text] [Related]
19. CFTR gating I: Characterization of the ATP-dependent gating of a phosphorylation-independent CFTR channel (DeltaR-CFTR).
Bompadre SG; Ai T; Cho JH; Wang X; Sohma Y; Li M; Hwang TC
J Gen Physiol; 2005 Apr; 125(4):361-75. PubMed ID: 15767295
[TBL] [Abstract][Full Text] [Related]
20. Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the nucleotide-binding domains.
Wang W; Bernard K; Li G; Kirk KL
J Biol Chem; 2007 Feb; 282(7):4533-4544. PubMed ID: 17178710
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
