475 related articles for article (PubMed ID: 25521189)
1. The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells.
Deng S; Yan T; Nikolova T; Fuhrmann D; Nemecek A; Gödtel-Armbrust U; Kaina B; Wojnowski L
Br J Pharmacol; 2015 May; 172(9):2246-57. PubMed ID: 25521189
[TBL] [Abstract][Full Text] [Related]
2. Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both topoisomerase II isoforms.
Deng S; Yan T; Jendrny C; Nemecek A; Vincetic M; Gödtel-Armbrust U; Wojnowski L
BMC Cancer; 2014 Nov; 14():842. PubMed ID: 25406834
[TBL] [Abstract][Full Text] [Related]
3. Topoisomerase II{alpha}-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin.
Yan T; Deng S; Metzger A; Gödtel-Armbrust U; Porter AC; Wojnowski L
Mol Cancer Ther; 2009 May; 8(5):1075-85. PubMed ID: 19417146
[TBL] [Abstract][Full Text] [Related]
4. NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells.
Wu SY; Pan SL; Xiao ZY; Hsu JL; Chen MC; Lee KH; Teng CM
PLoS One; 2014; 9(11):e112220. PubMed ID: 25372714
[TBL] [Abstract][Full Text] [Related]
5. DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac.
Wartlick F; Bopp A; Henninger C; Fritz G
Biochim Biophys Acta; 2013 Dec; 1833(12):3093-3103. PubMed ID: 23999236
[TBL] [Abstract][Full Text] [Related]
6. Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
Tamaichi H; Sato M; Porter AC; Shimizu T; Mizutani S; Takagi M
Cancer Sci; 2013 Feb; 104(2):178-84. PubMed ID: 23163762
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.
Zhao H; Traganos F; Darzynkiewicz Z
Cell Cycle; 2008 Oct; 7(19):3048-55. PubMed ID: 18802408
[TBL] [Abstract][Full Text] [Related]
8. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
[TBL] [Abstract][Full Text] [Related]
9. Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis.
Kurose A; Tanaka T; Huang X; Halicka HD; Traganos F; Dai W; Darzynkiewicz Z
Cytometry A; 2005 Nov; 68(1):1-9. PubMed ID: 16184611
[TBL] [Abstract][Full Text] [Related]
10. Induction of DNA damage and ATF3 by retigeric acid B, a novel topoisomerase II inhibitor, promotes apoptosis in prostate cancer cells.
Liu Y; Gao F; Jiang H; Niu L; Bi Y; Young CY; Yuan H; Lou H
Cancer Lett; 2013 Aug; 337(1):66-76. PubMed ID: 23693077
[TBL] [Abstract][Full Text] [Related]
11. DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
An J; Huang YC; Xu QZ; Zhou LJ; Shang ZF; Huang B; Wang Y; Liu XD; Wu DC; Zhou PK
BMC Mol Biol; 2010 Mar; 11():18. PubMed ID: 20205745
[TBL] [Abstract][Full Text] [Related]
12. Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses.
Fan JR; Peng AL; Chen HC; Lo SC; Huang TH; Li TK
DNA Repair (Amst); 2008 Mar; 7(3):452-63. PubMed ID: 18206427
[TBL] [Abstract][Full Text] [Related]
13. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
Kurz EU; Douglas P; Lees-Miller SP
J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
[TBL] [Abstract][Full Text] [Related]
14. Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.
Mirzayans R; Severin D; Murray D
Int J Radiat Oncol Biol Phys; 2006 Dec; 66(5):1498-505. PubMed ID: 17126209
[TBL] [Abstract][Full Text] [Related]
15. Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane.
Lyu YL; Kerrigan JE; Lin CP; Azarova AM; Tsai YC; Ban Y; Liu LF
Cancer Res; 2007 Sep; 67(18):8839-46. PubMed ID: 17875725
[TBL] [Abstract][Full Text] [Related]
16. CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines.
Pobst LJ; Ames MM
Cancer Chemother Pharmacol; 2006 May; 57(5):569-76. PubMed ID: 16096788
[TBL] [Abstract][Full Text] [Related]
17. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.
Rappold I; Iwabuchi K; Date T; Chen J
J Cell Biol; 2001 Apr; 153(3):613-20. PubMed ID: 11331310
[TBL] [Abstract][Full Text] [Related]
18. Most hydrogen peroxide-induced histone H2AX phosphorylation is mediated by ATR and is not dependent on DNA double-strand breaks.
Katsube T; Mori M; Tsuji H; Shiomi T; Wang B; Liu Q; Nenoi M; Onoda M
J Biochem; 2014 Aug; 156(2):85-95. PubMed ID: 24682951
[TBL] [Abstract][Full Text] [Related]
19. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.
Trinh BQ; Ko SY; Barengo N; Lin SY; Naora H
Cancer Res; 2013 Jan; 73(2):1000-10. PubMed ID: 23222298
[TBL] [Abstract][Full Text] [Related]
20. Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
Goodenow D; Emmanuel F; Berman C; Sahyouni M; Richardson C
Mutat Res Genet Toxicol Environ Mutagen; 2020 Jan; 849():503144. PubMed ID: 32087851
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
