BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 25525271)

  • 1. Epidermal growth factor activates the Rho GTPase-activating protein (GAP) Deleted in Liver Cancer 1 via focal adhesion kinase and protein phosphatase 2A.
    Ravi A; Kaushik S; Ravichandran A; Pan CQ; Low BC
    J Biol Chem; 2015 Feb; 290(7):4149-62. PubMed ID: 25525271
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK).
    Li G; Du X; Vass WC; Papageorge AG; Lowy DR; Qian X
    Proc Natl Acad Sci U S A; 2011 Oct; 108(41):17129-34. PubMed ID: 21969587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Concerted modulation of paxillin dynamics at focal adhesions by Deleted in Liver Cancer-1 and focal adhesion kinase during early cell spreading.
    Kaushik S; Ravi A; Hameed FM; Low BC
    Cytoskeleton (Hoboken); 2014 Dec; 71(12):677-94. PubMed ID: 25448629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions.
    Tripathi BK; Anderman MF; Qian X; Zhou M; Wang D; Papageorge AG; Lowy DR
    J Cell Biol; 2019 Sep; 218(9):3060-3076. PubMed ID: 31308216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
    Tripathi BK; Grant T; Qian X; Zhou M; Mertins P; Wang D; Papageorge AG; Tarasov SG; Hunter KW; Carr SA; Lowy DR
    J Cell Biol; 2017 Dec; 216(12):4255-4270. PubMed ID: 29114068
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function.
    Chan LK; Ko FC; Ng IO; Yam JW
    PLoS One; 2009; 4(5):e5572. PubMed ID: 19440389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons.
    Mao L; Yang L; Arora A; Choe ES; Zhang G; Liu Z; Fibuch EE; Wang JQ
    J Biol Chem; 2005 Apr; 280(13):12602-10. PubMed ID: 15661743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation.
    Cao X; Voss C; Zhao B; Kaneko T; Li SS
    Proc Natl Acad Sci U S A; 2012 Jan; 109(5):1455-60. PubMed ID: 22307599
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CDK5 is a major regulator of the tumor suppressor DLC1.
    Tripathi BK; Qian X; Mertins P; Wang D; Papageorge AG; Carr SA; Lowy DR
    J Cell Biol; 2014 Dec; 207(5):627-42. PubMed ID: 25452387
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Expression of deleted in liver cancer 1 and phosphorelated focal adhesion kinase in breast cancer].
    Feng Y; Zhou HX; Li JH; Li ZY; Cheng WG; Jin ML; He L
    Nan Fang Yi Ke Da Xue Xue Bao; 2011 Aug; 31(8):1448-51. PubMed ID: 21868344
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation.
    Scholz RP; Gustafsson JO; Hoffmann P; Jaiswal M; Ahmadian MR; Eisler SA; Erlmann P; Schmid S; Hausser A; Olayioye MA
    Exp Cell Res; 2011 Feb; 317(4):496-503. PubMed ID: 21087603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adhesion, actin cytoskeleton organisation and the spreading of colon adenocarcinoma cells induced by EGF are mediated by alpha2beta1 integrin low clustering through focal adhesion kinase.
    Pichard V; Honoré S; Kovacic H; Li C; Prevôt C; Briand C; Rognoni JB
    Histochem Cell Biol; 2001 Oct; 116(4):337-48. PubMed ID: 11702192
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DLC1 negatively regulates angiogenesis in a paracrine fashion.
    Shih YP; Liao YC; Lin Y; Lo SH
    Cancer Res; 2010 Nov; 70(21):8270-5. PubMed ID: 20861185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
    Yin G; Zheng Q; Yan C; Berk BC
    J Biol Chem; 2005 Jul; 280(30):27705-12. PubMed ID: 15923189
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma.
    Wong CC; Wong CM; Ko FC; Chan LK; Ching YP; Yam JW; Ng IO
    PLoS One; 2008 Jul; 3(7):e2779. PubMed ID: 18648664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The tumor suppressor protein DLC1 maintains protein kinase D activity and Golgi secretory function.
    Jensch A; Frey Y; Bitschar K; Weber P; Schmid S; Hausser A; Olayioye MA; Radde NE
    J Biol Chem; 2018 Sep; 293(37):14407-14416. PubMed ID: 30045871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration.
    Heering J; Erlmann P; Olayioye MA
    Exp Cell Res; 2009 Sep; 315(15):2505-14. PubMed ID: 19482022
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells.
    Shih YP; Takada Y; Lo SH
    Mol Cancer Res; 2012 Jan; 10(1):34-9. PubMed ID: 22064653
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration.
    Cao X; Kaneko T; Li JS; Liu AD; Voss C; Li SS
    Nat Commun; 2015 Jul; 6():7721. PubMed ID: 26166433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of deleted in liver cancer 1 tumor suppressor by protein-protein interactions and phosphorylation.
    Ko FC; Ping Yam JW
    Int J Cancer; 2014 Jul; 135(2):264-9. PubMed ID: 24114040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.