These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 25527335)

  • 1. MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
    Kia R; Kelly L; Sison-Young RL; Zhang F; Pridgeon CS; Heslop JA; Metcalfe P; Kitteringham NR; Baxter M; Harrison S; Hanley NA; Burke ZD; Storm MP; Welham MJ; Tosh D; Küppers-Munther B; Edsbagge J; Starkey Lewis PJ; Bonner F; Harpur E; Sidaway J; Bowes J; Fenwick SW; Malik H; Goldring CE; Park BK
    Toxicol Sci; 2015 Mar; 144(1):173-85. PubMed ID: 25527335
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of drug-induced immune-mediated hepatotoxicity using hepatocyte-like cells derived from human embryonic stem cells.
    Kim DE; Jang MJ; Kim YR; Lee JY; Cho EB; Kim E; Kim Y; Kim MY; Jeong WI; Kim S; Han YM; Lee SH
    Toxicology; 2017 Jul; 387():1-9. PubMed ID: 28645575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity.
    Choudhury Y; Toh YC; Xing J; Qu Y; Poh J; Li H; Tan HS; Kanesvaran R; Yu H; Tan MH
    Sci Rep; 2017 Jan; 7():41238. PubMed ID: 28120901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?
    Holman NS; Mosedale M; Wolf KK; LeCluyse EL; Watkins PB
    Toxicol Sci; 2016 Jun; 151(2):365-75. PubMed ID: 26962055
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.
    Ware BR; Berger DR; Khetani SR
    Toxicol Sci; 2015 Jun; 145(2):252-62. PubMed ID: 25716675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
    Gómez-Lechón MJ; Tolosa L
    Arch Toxicol; 2016 Sep; 90(9):2049-2061. PubMed ID: 27325232
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice.
    Woo DH; Kim SK; Lim HJ; Heo J; Park HS; Kang GY; Kim SE; You HJ; Hoeppner DJ; Kim Y; Kwon H; Choi TH; Lee JH; Hong SH; Song KW; Ahn EK; Chenoweth JG; Tesar PJ; McKay RD; Kim JH
    Gastroenterology; 2012 Mar; 142(3):602-11. PubMed ID: 22138358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).
    Li M; Yang Y; He ZX; Zhou ZW; Yang T; Guo P; Zhang X; Zhou SF
    Drug Metab Dispos; 2014 Jan; 42(1):44-61. PubMed ID: 24104199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells.
    Deguchi S; Yamashita T; Igai K; Harada K; Toba Y; Hirata K; Takayama K; Mizuguchi H
    Drug Metab Dispos; 2019 Jun; 47(6):632-638. PubMed ID: 30962288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of microRNA expressions for the identification of chemical hazards in in vivo and in vitro hepatic injury models.
    Hwang SR; Tham NTT; Lee SH; Bang JH; Yi H; Park YI; Lee HK; Kang HG; Kim YS; Woo GH; Ku HO
    J Appl Toxicol; 2019 Feb; 39(2):333-342. PubMed ID: 30264499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stem-cell derived hepatocyte-like cells for the assessment of drug-induced liver injury.
    Donato MT; Tolosa L
    Differentiation; 2019; 106():15-22. PubMed ID: 30844688
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular health.
    Krueger WH; Tanasijevic B; Barber V; Flamier A; Gu X; Manautou J; Rasmussen TP
    PLoS One; 2013; 8(7):e67296. PubMed ID: 23874411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.
    Szkolnicka D; Lucendo-Villarin B; Moore JK; Simpson KJ; Forbes SJ; Hay DC
    Stem Cells Transl Med; 2016 Jun; 5(6):764-72. PubMed ID: 27057006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Comparison of Mesenchymal Stem Cell-derived Hepatocyte-like Cells and HepG2 Cells for Use in Drug-Induced Liver Injury Studies.
    Perera D; Soysa P; Wijeratne S
    Altern Lab Anim; 2022 Mar; 50(2):146-155. PubMed ID: 35380478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative DNA damage contributes to usnic acid-induced toxicity in human induced pluripotent stem cell-derived hepatocytes.
    Gao X; Campasino K; Yourick MR; Cao Y; Yourick JJ; Sprando RL
    J Appl Toxicol; 2024 Sep; 44(9):1329-1346. PubMed ID: 38724177
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemically induced hepatotoxicity in human stem cell-induced hepatocytes compared with primary hepatocytes and HepG2.
    Kang SJ; Lee HM; Park YI; Yi H; Lee H; So B; Song JY; Kang HG
    Cell Biol Toxicol; 2016 Oct; 32(5):403-17. PubMed ID: 27287938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of microRNA-375 and microRNA-122 promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.
    Jaafarpour Z; Soleimani M; Hosseinkhani S; Geramizadeh B; Yaghmaei P; Mobarra N; Karimi MH
    Biologicals; 2020 Jan; 63():24-32. PubMed ID: 31882195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transplantation of hESC-derived hepatocytes protects mice from liver injury.
    Tolosa L; Caron J; Hannoun Z; Antoni M; López S; Burks D; Castell JV; Weber A; Gomez-Lechon MJ; Dubart-Kupperschmitt A
    Stem Cell Res Ther; 2015 Dec; 6():246. PubMed ID: 26652177
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA-199a-5p inhibition enhances the liver repopulation ability of human embryonic stem cell-derived hepatic cells.
    Möbus S; Yang D; Yuan Q; Lüdtke TH; Balakrishnan A; Sgodda M; Rani B; Kispert A; Araúzo-Bravo MJ; Vogel A; Manns MP; Ott M; Cantz T; Sharma AD
    J Hepatol; 2015 Jan; 62(1):101-10. PubMed ID: 25135862
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
    Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
    Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.