134 related articles for article (PubMed ID: 2552762)
1. Leukotriene (LT) receptor antagonists. Heterocycle-linked tetrazoles and carboxylic acids. LY203647.
Marshall WS; Sigmund SK; Whitesitt CA; Lifer SL; Roman CR; Rinkema LE; Hahn RA; Fleisch JH
Agents Actions; 1989 Jun; 27(3-4):309-12. PubMed ID: 2552762
[TBL] [Abstract][Full Text] [Related]
2. Leukotriene receptor antagonists. 2. The [[(tetrazol-5-ylaryl)oxy]methyl]acetophenone derivatives.
Dillard RD; Carr FP; McCullough D; Haisch KD; Rinkema LE; Fleisch JH
J Med Chem; 1987 May; 30(5):911-8. PubMed ID: 3033245
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationships (SAR) of the 3-alkyl substituents among a series of hydroxy-acetophenone leukotriene antagonists.
Marshall WS; Whitesitt CA; Goodson T; Roman C; Rinkema L; Fleisch JH
Agents Actions; 1987 Aug; 21(3-4):275-7. PubMed ID: 3687580
[TBL] [Abstract][Full Text] [Related]
4. Leukotriene receptor antagonism and augmentation of beta-receptor-mediated events by LY171883.
Rinkema LE; Roman CR; Russell WL; Spaethe SM; Bemis KG; Henry DP; Marshall WS; Fleisch JH
J Pharm Pharmacol; 1990 Sep; 42(9):620-5. PubMed ID: 1706765
[TBL] [Abstract][Full Text] [Related]
5. The effect of an orally active leukotriene D4/E4 antagonist, LY171883, on antigen-induced airway responses in allergic sheep.
Abraham WM; Wanner A; Stevenson JS; Chapman GA
Prostaglandins; 1986 Mar; 31(3):457-67. PubMed ID: 3754973
[TBL] [Abstract][Full Text] [Related]
6. (Phenylmethoxy)phenyl derivatives of omega-oxo- and omega-tetrazolylalkanoic acids and related tetrazoles. Synthesis and evaluation as leukotriene D4 receptor antagonists.
Dillard RD; Hahn RA; McCullough D; Carr FP; Rinkema LE; Roman CR; Fleisch JH
J Med Chem; 1991 Sep; 34(9):2768-78. PubMed ID: 1654427
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of LY203647 on cardiovascular leukotriene D4 receptors and myocardial reperfusion injury.
Hahn RA; MacDonald BR; Morgan E; Potts BD; Parli CJ; Rinkema LE; Whitesitt CA; Marshall WS
J Pharmacol Exp Ther; 1992 Mar; 260(3):979-89. PubMed ID: 1312172
[TBL] [Abstract][Full Text] [Related]
8. N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
Musser JH; Kreft AF; Bender RH; Kubrak DM; Grimes D; Carlson RP; Hand JM; Chang J
J Med Chem; 1990 Jan; 33(1):240-5. PubMed ID: 2104935
[TBL] [Abstract][Full Text] [Related]
9. A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
Fleisch JH; Cloud ML; Marshall WS
Ann N Y Acad Sci; 1988; 524():356-68. PubMed ID: 2837970
[No Abstract] [Full Text] [Related]
10. LY171883, 1-less than 2-hydroxy-3-propyl-4-less than 4-(1H-tetrazol-5-yl) butoxy greater than phenyl greater than ethanone, an orally active leukotriene D4 antagonist.
Fleisch JH; Rinkema LE; Haisch KD; Swanson-Bean D; Goodson T; Ho PP; Marshall WS
J Pharmacol Exp Ther; 1985 Apr; 233(1):148-57. PubMed ID: 3981452
[TBL] [Abstract][Full Text] [Related]
11. Primate myocardial and systemic hemodynamic responses to leukotriene D4: antagonism by LY171883.
Hahn RA; MacDonald BR
J Pharmacol Exp Ther; 1987 Jul; 242(1):62-9. PubMed ID: 3612538
[TBL] [Abstract][Full Text] [Related]
12. Protective effect of a selective leukotriene antagonist in endotoxemia in the rat.
Cook JA; Wise WC; Halushka PV
J Pharmacol Exp Ther; 1985 Nov; 235(2):470-4. PubMed ID: 2997435
[TBL] [Abstract][Full Text] [Related]
13. The pharmacological evaluation of LY 170680, a novel leukotriene D4 and E4 antagonist in the guinea-pig.
Boot JR; Bond A; Gooderham R; O'Brien A; Parsons M; Thomas KH
Br J Pharmacol; 1989 Sep; 98(1):259-67. PubMed ID: 2553189
[TBL] [Abstract][Full Text] [Related]
14. Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives.
Marshall WS; Goodson T; Cullinan GJ; Swanson-Bean D; Haisch KD; Rinkema LE; Fleisch JH
J Med Chem; 1987 Apr; 30(4):682-9. PubMed ID: 3031291
[TBL] [Abstract][Full Text] [Related]
15. Leukotriene receptor antagonists. 4. Synthesis and leukotriene D4/E4 receptor antagonist activity of 4-(alkyl)acetophenone derivatives.
Gapinski DM; Roman CR; Rinkema LE; Fleisch JH
J Med Chem; 1988 Jan; 31(1):172-5. PubMed ID: 2826785
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of LY163443, 1-[2-hydroxy-3-propyl-4-([4- (1H-tetrazol-5-ylmethyl)phenoxy]methyl) phenyl]ethanone, as a pharmacologic antagonist of leukotrienes D4 and E4.
Fleisch JH; Rinkema LE; Haisch KD; McCullough D; Carr FP; Dillard RD
Naunyn Schmiedebergs Arch Pharmacol; 1986 May; 333(1):70-7. PubMed ID: 3016562
[TBL] [Abstract][Full Text] [Related]
17. Leukotriene B4 receptor antagonists: the LY255283 series of hydroxyacetophenones.
Herron DK; Goodson T; Bollinger NG; Swanson-Bean D; Wright IG; Staten GS; Thompson AR; Froelich LL; Jackson WT
J Med Chem; 1992 May; 35(10):1818-28. PubMed ID: 1316967
[TBL] [Abstract][Full Text] [Related]
18. Dose-related antagonism of leukotriene D4-induced bronchoconstriction by p.o. administration of LY-171883 in nonasthmatic subjects.
Phillips GD; Rafferty P; Robinson C; Holgate ST
J Pharmacol Exp Ther; 1988 Aug; 246(2):732-8. PubMed ID: 3404455
[TBL] [Abstract][Full Text] [Related]
19. The preclinical pharmacology of ICI 204,219. A peptide leukotriene antagonist.
Krell RD; Aharony D; Buckner CK; Keith RA; Kusner EJ; Snyder DW; Bernstein PR; Matassa VG; Yee YK; Brown FJ
Am Rev Respir Dis; 1990 Apr; 141(4 Pt 1):978-87. PubMed ID: 2158259
[TBL] [Abstract][Full Text] [Related]
20. The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency.
Galemmo RA; Johnson WH; Learn KS; Lee TD; Huang FC; Campbell HF; Youssefyeh R; O'Rourke SV; Schuessler G; Sweeney DM
J Med Chem; 1990 Oct; 33(10):2828-41. PubMed ID: 2170649
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
