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5. ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model. Horizoe T; Nagakura N; Chiba K; Shirota H; Shinoda M; Kobayashi N; Numata H; Okamoto Y; Kobayashi S Inflamm Res; 1998 Oct; 47(10):375-83. PubMed ID: 9831321 [TBL] [Abstract][Full Text] [Related]
6. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile. Argentieri DC; Ritchie DM; Ferro MP; Kirchner T; Wachter MP; Anderson DW; Rosenthale ME; Capetola RJ J Pharmacol Exp Ther; 1994 Dec; 271(3):1399-408. PubMed ID: 7996452 [TBL] [Abstract][Full Text] [Related]
7. Failure of the inhibition of rat gastric mucosal 5-lipoxygenase by novel acetohydroxamic acids to prevent ethanol-induced damage. Boughton-Smith NK; Whittle BJ Br J Pharmacol; 1988 Sep; 95(1):155-62. PubMed ID: 3146394 [TBL] [Abstract][Full Text] [Related]
8. Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase. Flynn DL; Capiris T; Cetenko WJ; Connor DT; Dyer RD; Kostlan CR; Nies DE; Schrier DJ; Sircar JC J Med Chem; 1990 Aug; 33(8):2070-2. PubMed ID: 2115586 [No Abstract] [Full Text] [Related]
9. Pharmacology of the dual inhibitor of cyclooxygenase and 5-lipoxygenase 3-hydroxy-5-trifluoromethyl-N-(2-(2-thienyl)-2-phenyl-ethenyl)-benzo (b)thiophene-2-carboxamide. Bailey PJ; Dallob AL; Allison DL; Anderson RL; Bach T; Durette PL; Hand KM; Hopple SL; Luell S; Meurer R Arzneimittelforschung; 1988 Mar; 38(3):372-8. PubMed ID: 3132928 [TBL] [Abstract][Full Text] [Related]
10. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. Kirchner T; Argentieri DC; Barbone AG; Singer M; Steber M; Ansell J; Beers SA; Wachter MP; Wu W; Malloy E; Stewart A; Ritchie DM J Pharmacol Exp Ther; 1997 Aug; 282(2):1094-101. PubMed ID: 9262379 [TBL] [Abstract][Full Text] [Related]
11. The effects of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal antiinflammatory drugs in mice. Rainsford KD Agents Actions; 1987 Aug; 21(3-4):316-9. PubMed ID: 3687587 [No Abstract] [Full Text] [Related]
12. Antiinflammatory 2,6-di-tert-butyl-4-(2-arylethenyl)phenols. Lazer ES; Wong HC; Possanza GJ; Graham AG; Farina PR J Med Chem; 1989 Jan; 32(1):100-4. PubMed ID: 2491889 [TBL] [Abstract][Full Text] [Related]
13. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: effects on acute inflammatory responses. Higgs GA; Follenfant RL; Garland LG Br J Pharmacol; 1988 Jun; 94(2):547-51. PubMed ID: 2840161 [TBL] [Abstract][Full Text] [Related]
14. Arachidonic acid-induced pleurisy (ARIP): an in vivo model for testing 5-lipoxygenase inhibition. Boctor AM; Burke C; Hovinga ME Methods Find Exp Clin Pharmacol; 1987 Dec; 9(12):793-7. PubMed ID: 2831442 [TBL] [Abstract][Full Text] [Related]
15. Suppression of experimental autoimmune encephalomyelitis by dual cyclo-oxygenase and 5-lipoxygenase inhibition. Prosiegel M; Neu I; Mallinger J; Wildfeuer A; Mehlber L; Vogl S; Hoffmann G; Ruhenstroth-Bauer G Acta Neurol Scand; 1989 Mar; 79(3):223-6. PubMed ID: 2541593 [TBL] [Abstract][Full Text] [Related]
16. The antiinflammatory action of guanabenz is mediated through 5-lipoxygenase and cyclooxygenase inhibition. Chang J; Blazek E; Skowronek M; Marinari L; Carlson RP Eur J Pharmacol; 1987 Oct; 142(2):197-205. PubMed ID: 3121363 [TBL] [Abstract][Full Text] [Related]
17. Discovery of (2-fluoro-benzyl)-(2-methyl-2-phenethyl-2H-chromen-6-yl)-amine (KRH-102140) as an orally active 5-lipoxygenase inhibitor with activity in murine inflammation models. Cho YS; Song JS; Huh JY; Kim CH; Gong YD; Cheon HG Pharmacology; 2011; 87(1-2):49-55. PubMed ID: 21212714 [TBL] [Abstract][Full Text] [Related]
18. 1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity. Mylari BL; Carty TJ; Moore PF; Zembrowski WJ J Med Chem; 1990 Jul; 33(7):2019-24. PubMed ID: 2113951 [TBL] [Abstract][Full Text] [Related]
19. Anti-inflammatory effect of YPE-01, a novel diarylheptanoid derivative, on dermal inflammation in mice. Yamazaki R; Aiyama R; Matsuzaki T; Hashimoto S; Yokokura T Inflamm Res; 1998 Apr; 47(4):182-6. PubMed ID: 9628261 [TBL] [Abstract][Full Text] [Related]
20. [Inhibition of arachidonic acid-induced ear edema in the mouse with lipoxygenase-, cyclo-oxygenase- and dual inhibitors]. Zarnack S; Bekemeier H; Giessler AJ Pharmazie; 1988 May; 43(5):337-8. PubMed ID: 3140256 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]