BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 25531914)

  • 1. RANK ligand blockade with denosumab in combination with sorafenib in chemorefractory osteosarcoma: a possible step forward?
    Cathomas R; Rothermundt C; Bode B; Fuchs B; von Moos R; Schwitter M
    Oncology; 2015; 88(4):257-60. PubMed ID: 25531914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial.
    Grignani G; Palmerini E; Ferraresi V; D'Ambrosio L; Bertulli R; Asaftei SD; Tamburini A; Pignochino Y; Sangiolo D; Marchesi E; Capozzi F; Biagini R; Gambarotti M; Fagioli F; Casali PG; Picci P; Ferrari S; Aglietta M;
    Lancet Oncol; 2015 Jan; 16(1):98-107. PubMed ID: 25498219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 upregulation in osteosarcoma preclinical models.
    Pignochino Y; Dell'Aglio C; Basiricò M; Capozzi F; Soster M; Marchiò S; Bruno S; Gammaitoni L; Sangiolo D; Torchiaro E; D'Ambrosio L; Fagioli F; Ferrari S; Alberghini M; Picci P; Aglietta M; Grignani G
    Clin Cancer Res; 2013 Apr; 19(8):2117-31. PubMed ID: 23434734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of RANK ligand and denosumab, a targeted RANK ligand inhibitor, in bone health and osteoporosis: a review of preclinical and clinical data.
    Dempster DW; Lambing CL; Kostenuik PJ; Grauer A
    Clin Ther; 2012 Mar; 34(3):521-36. PubMed ID: 22440513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone.
    Branstetter DG; Nelson SD; Manivel JC; Blay JY; Chawla S; Thomas DM; Jun S; Jacobs I
    Clin Cancer Res; 2012 Aug; 18(16):4415-24. PubMed ID: 22711702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Denosumab: benefits of RANK ligand inhibition in cancer patients.
    Lipton A; Jacobs I
    Curr Opin Support Palliat Care; 2011 Sep; 5(3):258-64. PubMed ID: 21826000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RANKL, denosumab, and giant cell tumor of bone.
    Thomas DM
    Curr Opin Oncol; 2012 Jul; 24(4):397-403. PubMed ID: 22581354
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RANKL expression is related to treatment outcome of patients with localized, high-grade osteosarcoma.
    Lee JA; Jung JS; Kim DH; Lim JS; Kim MS; Kong CB; Song WS; Cho WH; Jeon DG; Lee SY; Koh JS
    Pediatr Blood Cancer; 2011 May; 56(5):738-43. PubMed ID: 21370405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial.
    Serve H; Krug U; Wagner R; Sauerland MC; Heinecke A; Brunnberg U; Schaich M; Ottmann O; Duyster J; Wandt H; Fischer T; Giagounidis A; Neubauer A; Reichle A; Aulitzky W; Noppeney R; Blau I; Kunzmann V; Stuhlmann R; Krämer A; Kreuzer KA; Brandts C; Steffen B; Thiede C; Müller-Tidow C; Ehninger G; Berdel WE
    J Clin Oncol; 2013 Sep; 31(25):3110-8. PubMed ID: 23897964
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study.
    Thomas D; Henshaw R; Skubitz K; Chawla S; Staddon A; Blay JY; Roudier M; Smith J; Ye Z; Sohn W; Dansey R; Jun S
    Lancet Oncol; 2010 Mar; 11(3):275-80. PubMed ID: 20149736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sorafenib and bevacizumab combination targeted therapy in advanced neuroendocrine tumour: a phase II study of Spanish Neuroendocrine Tumour Group (GETNE0801).
    Castellano D; Capdevila J; Sastre J; Alonso V; Llanos M; García-Carbonero R; Manzano Mozo JL; Sevilla I; Durán I; Salazar R
    Eur J Cancer; 2013 Dec; 49(18):3780-7. PubMed ID: 24012098
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phase I pharmacokinetic and pharmacodynamic study of lapatinib in combination with sorafenib in patients with advanced refractory solid tumors.
    Simonelli M; Zucali PA; Lorenzi E; Rubino L; De Vincenzo F; De Sanctis R; Perrino M; Mancini L; Di Tommaso L; Rimassa L; Masci G; Zuradelli M; Suter MB; Bertossi M; Fattuzzo G; Giordano L; Roncalli MG; Santoro A
    Eur J Cancer; 2013 Mar; 49(5):989-98. PubMed ID: 23146956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sorafenib in patients with refractory or recurrent multiple myeloma.
    Yordanova A; Hose D; Neben K; Witzens-Harig M; Gütgemann I; Raab MS; Moehler T; Goldschmidt H; Schmidt-Wolf IG
    Hematol Oncol; 2013 Dec; 31(4):197-200. PubMed ID: 23494836
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Denosumab for treatment of breast cancer bone metastases and beyond.
    Nangia JR; Ma JD; Nguyen CM; Mendes MA; Trivedi MV
    Expert Opin Biol Ther; 2012 Apr; 12(4):491-501. PubMed ID: 22348344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase II study evaluating the efficacy, safety, and pharmacodynamic correlative study of dual antiangiogenic inhibition using bevacizumab in combination with sorafenib in patients with advanced malignant melanoma.
    Mahalingam D; Malik L; Beeram M; Rodon J; Sankhala K; Mita A; Benjamin D; Ketchum N; Michalek J; Tolcher A; Wright J; Sarantopoulos J
    Cancer Chemother Pharmacol; 2014 Jul; 74(1):77-84. PubMed ID: 24817603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation.
    Armstrong AE; Walterhouse DO; Leavey PJ; Reichek J; Walz AL
    Pediatr Blood Cancer; 2019 Jan; 66(1):e27493. PubMed ID: 30318721
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Giant cell tumour of bone.
    Thomas DM; Skubitz KM
    Curr Opin Oncol; 2009 Jul; 21(4):338-44. PubMed ID: 19444102
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Denosumab: Current Use in the Treatment of Primary Bone Tumors.
    Savvidou OD; Bolia IK; Chloros GD; Papanastasiou J; Koutsouradis P; Papagelopoulos PJ
    Orthopedics; 2017 Jul; 40(4):204-210. PubMed ID: 28732103
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formulated siRNAs targeting Rankl prevent osteolysis and enhance chemotherapeutic response in osteosarcoma models.
    Rousseau J; Escriou V; Lamoureux F; Brion R; Chesneau J; Battaglia S; Amiaud J; Scherman D; Heymann D; Rédini F; Trichet V
    J Bone Miner Res; 2011 Oct; 26(10):2452-62. PubMed ID: 21713988
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells.
    Wittrant Y; Lamoureux F; Mori K; Riet A; Kamijo A; Heymann D; Redini F
    Int J Oncol; 2006 Jan; 28(1):261-9. PubMed ID: 16328004
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.