278 related articles for article (PubMed ID: 25538235)
1. Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex.
Meng S; Cao J; He Q; Xiong L; Chang E; Radovick S; Wondisford FE; He L
J Biol Chem; 2015 Feb; 290(6):3793-802. PubMed ID: 25538235
[TBL] [Abstract][Full Text] [Related]
2. Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).
Cao J; Meng S; Chang E; Beckwith-Fickas K; Xiong L; Cole RN; Radovick S; Wondisford FE; He L
J Biol Chem; 2014 Jul; 289(30):20435-46. PubMed ID: 24928508
[TBL] [Abstract][Full Text] [Related]
3. The importance of the AMPK gamma 1 subunit in metformin suppression of liver glucose production.
An H; Wang Y; Qin C; Li M; Maheshwari A; He L
Sci Rep; 2020 Jun; 10(1):10482. PubMed ID: 32591547
[TBL] [Abstract][Full Text] [Related]
4. Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action.
Bang S; Chen Y; Ahima RS; Kim SF
Mol Endocrinol; 2014 Jul; 28(7):1186-93. PubMed ID: 24877601
[TBL] [Abstract][Full Text] [Related]
5. Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner.
Rattan R; Giri S; Hartmann LC; Shridhar V
J Cell Mol Med; 2011 Jan; 15(1):166-78. PubMed ID: 19874425
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
Xie Z; Dong Y; Scholz R; Neumann D; Zou MH
Circulation; 2008 Feb; 117(7):952-62. PubMed ID: 18250273
[TBL] [Abstract][Full Text] [Related]
7. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Foretz M; Hébrard S; Leclerc J; Zarrinpashneh E; Soty M; Mithieux G; Sakamoto K; Andreelli F; Viollet B
J Clin Invest; 2010 Jul; 120(7):2355-69. PubMed ID: 20577053
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of serine 399 in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation.
Zhu H; Moriasi CM; Zhang M; Zhao Y; Zou MH
J Biol Chem; 2013 Jun; 288(23):16495-16505. PubMed ID: 23612973
[TBL] [Abstract][Full Text] [Related]
9. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
Lin CC; Yeh HH; Huang WL; Yan JJ; Lai WW; Su WP; Chen HH; Su WC
Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
[TBL] [Abstract][Full Text] [Related]
10. AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells.
Zang M; Zuccollo A; Hou X; Nagata D; Walsh K; Herscovitz H; Brecher P; Ruderman NB; Cohen RA
J Biol Chem; 2004 Nov; 279(46):47898-905. PubMed ID: 15371448
[TBL] [Abstract][Full Text] [Related]
11. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism.
Hawley SA; Gadalla AE; Olsen GS; Hardie DG
Diabetes; 2002 Aug; 51(8):2420-5. PubMed ID: 12145153
[TBL] [Abstract][Full Text] [Related]
12. Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species.
Zou MH; Kirkpatrick SS; Davis BJ; Nelson JS; Wiles WG; Schlattner U; Neumann D; Brownlee M; Freeman MB; Goldman MH
J Biol Chem; 2004 Oct; 279(42):43940-51. PubMed ID: 15265871
[TBL] [Abstract][Full Text] [Related]
13. Role of AMP-activated protein kinase in mechanism of metformin action.
Zhou G; Myers R; Li Y; Chen Y; Shen X; Fenyk-Melody J; Wu M; Ventre J; Doebber T; Fujii N; Musi N; Hirshman MF; Goodyear LJ; Moller DE
J Clin Invest; 2001 Oct; 108(8):1167-74. PubMed ID: 11602624
[TBL] [Abstract][Full Text] [Related]
14. Activation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production.
He L; Chang E; Peng J; An H; McMillin SM; Radovick S; Stratakis CA; Wondisford FE
J Biol Chem; 2016 May; 291(20):10562-70. PubMed ID: 27002150
[TBL] [Abstract][Full Text] [Related]
15. Ptc1 protein phosphatase 2C contributes to glucose regulation of SNF1/AMP-activated protein kinase (AMPK) in Saccharomyces cerevisiae.
Ruiz A; Xu X; Carlson M
J Biol Chem; 2013 Oct; 288(43):31052-8. PubMed ID: 24019512
[TBL] [Abstract][Full Text] [Related]
16. Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status.
Stephenne X; Foretz M; Taleux N; van der Zon GC; Sokal E; Hue L; Viollet B; Guigas B
Diabetologia; 2011 Dec; 54(12):3101-10. PubMed ID: 21947382
[TBL] [Abstract][Full Text] [Related]
17. Bidirectional regulation of adenosine 5'-monophosphate-activated protein kinase activity by berberine and metformin in response to changes in ambient glucose concentration.
Xiao Y; Xu M; Alimujiang M; Bao Y; Wei L; Yin J
J Cell Biochem; 2018 Dec; 119(12):9910-9920. PubMed ID: 30129983
[TBL] [Abstract][Full Text] [Related]
18. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Shaw RJ; Lamia KA; Vasquez D; Koo SH; Bardeesy N; Depinho RA; Montminy M; Cantley LC
Science; 2005 Dec; 310(5754):1642-6. PubMed ID: 16308421
[TBL] [Abstract][Full Text] [Related]
19. Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.
Nakatsu Y; Iwashita M; Sakoda H; Ono H; Nagata K; Matsunaga Y; Fukushima T; Fujishiro M; Kushiyama A; Kamata H; Takahashi S; Katagiri H; Honda H; Kiyonari H; Uchida T; Asano T
J Biol Chem; 2015 Oct; 290(40):24255-66. PubMed ID: 26276391
[TBL] [Abstract][Full Text] [Related]
20. AMPK is a direct adenylate charge-regulated protein kinase.
Oakhill JS; Steel R; Chen ZP; Scott JW; Ling N; Tam S; Kemp BE
Science; 2011 Jun; 332(6036):1433-5. PubMed ID: 21680840
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
