202 related articles for article (PubMed ID: 25541002)
1. Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases.
Camara K; Kamat SS; Lasota CC; Cravatt BF; Howell AR
Bioorg Med Chem Lett; 2015 Jan; 25(2):317-21. PubMed ID: 25541002
[TBL] [Abstract][Full Text] [Related]
2. Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.
Zuhl AM; Mohr JT; Bachovchin DA; Niessen S; Hsu KL; Berlin JM; Dochnahl M; López-Alberca MP; Fu GC; Cravatt BF
J Am Chem Soc; 2012 Mar; 134(11):5068-71. PubMed ID: 22400490
[TBL] [Abstract][Full Text] [Related]
3. Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition.
Chang JW; Cognetta AB; Niphakis MJ; Cravatt BF
ACS Chem Biol; 2013 Jul; 8(7):1590-9. PubMed ID: 23701408
[TBL] [Abstract][Full Text] [Related]
4. Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived β-lactone.
Lajkiewicz NJ; Cognetta AB; Niphakis MJ; Cravatt BF; Porco JA
J Am Chem Soc; 2014 Feb; 136(6):2659-64. PubMed ID: 24447064
[TBL] [Abstract][Full Text] [Related]
5. Development of a Multiplexed Activity-Based Protein Profiling Assay to Evaluate Activity of Endocannabinoid Hydrolase Inhibitors.
Janssen APA; van der Vliet D; Bakker AT; Jiang M; Grimm SH; Campiani G; Butini S; van der Stelt M
ACS Chem Biol; 2018 Sep; 13(9):2406-2413. PubMed ID: 30199617
[TBL] [Abstract][Full Text] [Related]
6. Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors.
Lall MS; Ramtohul YK; James MN; Vederas JC
J Org Chem; 2002 Mar; 67(5):1536-47. PubMed ID: 11871884
[TBL] [Abstract][Full Text] [Related]
7. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors.
Adibekian A; Martin BR; Wang C; Hsu KL; Bachovchin DA; Niessen S; Hoover H; Cravatt BF
Nat Chem Biol; 2011 May; 7(7):469-78. PubMed ID: 21572424
[TBL] [Abstract][Full Text] [Related]
8. Profiling serine hydrolase activities in complex proteomes.
Kidd D; Liu Y; Cravatt BF
Biochemistry; 2001 Apr; 40(13):4005-15. PubMed ID: 11300781
[TBL] [Abstract][Full Text] [Related]
9. Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase.
Compton CL; Schmitz KR; Sauer RT; Sello JK
ACS Chem Biol; 2013 Dec; 8(12):2669-77. PubMed ID: 24047344
[TBL] [Abstract][Full Text] [Related]
10. Beta-lactones as a new class of cysteine proteinase inhibitors: inhibition of hepatitis A virus 3C proteinase by N-Cbz-serine beta-lactone.
Lall MS; Karvellas C; Vederas JC
Org Lett; 1999 Sep; 1(5):803-6. PubMed ID: 10823207
[TBL] [Abstract][Full Text] [Related]
11. Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.
Weir MP; Bethell SS; Cleasby A; Campbell CJ; Dennis RJ; Dix CJ; Finch H; Jhoti H; Mooney CJ; Patel S; Tang CM; Ward M; Wonacott AJ; Wharton CW
Biochemistry; 1998 May; 37(19):6645-57. PubMed ID: 9578548
[TBL] [Abstract][Full Text] [Related]
12. Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases.
Cognetta AB; Niphakis MJ; Lee HC; Martini ML; Hulce JJ; Cravatt BF
Chem Biol; 2015 Jul; 22(7):928-37. PubMed ID: 26120000
[TBL] [Abstract][Full Text] [Related]
13. Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling.
Hoover HS; Blankman JL; Niessen S; Cravatt BF
Bioorg Med Chem Lett; 2008 Nov; 18(22):5838-41. PubMed ID: 18657971
[TBL] [Abstract][Full Text] [Related]
14. Enol lactone inhibitors of serine proteases. The effect of regiochemistry on the inactivation behavior of phenyl-substituted (halomethylene)tetra- and -dihydrofuranones and (halomethylene)tetrahydropyranones toward alpha-chymotrypsin: stable acyl enzyme intermediate.
Sofia MJ; Katzenellenbogen JA
J Med Chem; 1986 Feb; 29(2):230-8. PubMed ID: 3512826
[TBL] [Abstract][Full Text] [Related]
15. Albocycline- and carbomycin-type macrolides, inhibitors of human prolyl endopeptidases.
Christner C; Küllertz G; Fischer G; Zerlin M; Grabley S; Thiericke R; Taddei A; Zeeck A
J Antibiot (Tokyo); 1998 Mar; 51(3):368-71. PubMed ID: 9589074
[No Abstract] [Full Text] [Related]
16. Guanidinophenyl-substituted enol lactones as selective, mechanism-based inhibitors of trypsin-like serine proteases.
Rai R; Katzenellenbogen JA
J Med Chem; 1992 Oct; 35(22):4150-9. PubMed ID: 1433218
[TBL] [Abstract][Full Text] [Related]
17. Competitive ABPP of Serine Hydrolases: A Case Study on DAGL-Alpha.
Baggelaar MP; Van der Stelt M
Methods Mol Biol; 2017; 1491():161-169. PubMed ID: 27778288
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationships of a new class of 1-oxacephem-based human chymase inhibitors.
Aoyama Y; Uenaka M; Konoike T; Iso Y; Nishitani Y; Kanda A; Naya N; Nakajima M
Bioorg Med Chem Lett; 2000 Nov; 10(21):2397-401. PubMed ID: 11078187
[TBL] [Abstract][Full Text] [Related]
19. Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes.
Lanier M; Cole DC; Istratiy Y; Klein MG; Schwartz PA; Tjhen R; Jennings A; Hixon MS
J Med Chem; 2017 Jun; 60(12):5209-5215. PubMed ID: 28564542
[TBL] [Abstract][Full Text] [Related]
20. The relationship between inhibitors of eukaryotic and prokaryotic serine proteases.
Konaklieva MI; Plotkin BJ
Mini Rev Med Chem; 2004 Sep; 4(7):721-39. PubMed ID: 15379640
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]