BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 25541388)

  • 1. Pharmacophore based virtual screening, synthesis and SAR of novel inhibitors of Mycobacterium sulfotransferase.
    Saha R; Tanwar O; Alam MM; Zaman MS; Khan SA; Akhter M
    Bioorg Med Chem Lett; 2015 Feb; 25(3):701-7. PubMed ID: 25541388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand based virtual screening and biological evaluation of inhibitors of chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv.
    Agrawal H; Kumar A; Bal NC; Siddiqi MI; Arora A
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3053-8. PubMed ID: 17418569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmacophore models.
    Gopalakrishnan B; Aparna V; Jeevan J; Ravi M; Desiraju GR
    J Chem Inf Model; 2005; 45(4):1101-8. PubMed ID: 16045305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel InhA reductase inhibitors: application of pharmacophore- and shape-based screening approach.
    Kumar UC; Bvs SK; Mahmood S; D S; Kumar-Sahu P; Pulakanam S; Ballell L; Alvarez-Gomez D; Malik S; Jarp S
    Future Med Chem; 2013 Mar; 5(3):249-59. PubMed ID: 23464516
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of HIV-1 integrase inhibitors: pharmacophore mapping, virtual screening, molecular docking, synthesis, and biological evaluation.
    Bhatt H; Patel P; Pannecouque C
    Chem Biol Drug Des; 2014 Feb; 83(2):154-66. PubMed ID: 23957390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of selective DprE1 inhibitors: Design, synthesis, crystal structure and antitubercular activity of benzothiazolylpyrimidine-5-carboxamides.
    Chikhale R; Menghani S; Babu R; Bansode R; Bhargavi G; Karodia N; Rajasekharan MV; Paradkar A; Khedekar P
    Eur J Med Chem; 2015; 96():30-46. PubMed ID: 25874329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel inhibitors against Mycobacterium tuberculosis L-alanine dehydrogenase (MTB-AlaDH) through structure-based virtual screening.
    Saxena S; Devi PB; Soni V; Yogeeswari P; Sriram D
    J Mol Graph Model; 2014 Feb; 47():37-43. PubMed ID: 24316937
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural comparison of Mtb-DHFR and h-DHFR for design, synthesis and evaluation of selective non-pteridine analogues as antitubercular agents.
    Sharma K; Tanwar O; Sharma S; Ali S; Alam MM; Zaman MS; Akhter M
    Bioorg Chem; 2018 Oct; 80():319-333. PubMed ID: 29986181
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of novel inhibitors of Mycobacterium tuberculosis MurG: homology modelling, structure based pharmacophore, molecular docking, and molecular dynamics simulations.
    Saxena S; Abdullah M; Sriram D; Guruprasad L
    J Biomol Struct Dyn; 2018 Sep; 36(12):3184-3198. PubMed ID: 28948866
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Knowledge based identification of potent antitubercular compounds using structure based virtual screening and structure interaction fingerprints.
    Kumar A; Chaturvedi V; Bhatnagar S; Sinha S; Siddiqi MI
    J Chem Inf Model; 2009 Jan; 49(1):35-42. PubMed ID: 19063713
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insight into Mycobacterium tuberculosis maltosyl transferase inhibitors: pharmacophore-based virtual screening, docking, and molecular dynamics simulations.
    Sengupta S; Roy D; Bandyopadhyay S
    J Biomol Struct Dyn; 2015; 33(12):2655-66. PubMed ID: 25669125
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Virtual screening and synthesis of novel antitubercular agents through interaction-based pharmacophore and molecular docking studies.
    Bhattarai D; Muddassar M; Jang JW; Hong SK; Kim EE; Oh T; Cho SN; Pae AN; Keum G
    Curr Comput Aided Drug Des; 2014; 10(4):383-92. PubMed ID: 25872944
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based virtual screening as a tool for the identification of novel inhibitors against Mycobacterium tuberculosis 3-dehydroquinate dehydratase.
    Petersen GO; Saxena S; Renuka J; Soni V; Yogeeswari P; Santos DS; Bizarro CV; Sriram D
    J Mol Graph Model; 2015 Jul; 60():124-31. PubMed ID: 26043661
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacophore modeling, virtual screening, docking and in silico ADMET analysis of protein kinase B (PKB β) inhibitors.
    Vyas VK; Ghate M; Goel A
    J Mol Graph Model; 2013 May; 42():17-25. PubMed ID: 23507201
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Gasse C; Huteau V; Douguet D; Munier-Lehmann H; Pochet S
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1057-61. PubMed ID: 18058536
    [No Abstract]   [Full Text] [Related]  

  • 16. 3D-QSAR studies and shape based virtual screening for identification of novel hits to inhibit MbtA in Mycobacterium tuberculosis.
    Maganti L; ; Ghoshal N
    J Biomol Struct Dyn; 2015; 33(2):344-64. PubMed ID: 24417439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
    Fullam E; Talbot J; Abuhammed A; Westwood I; Davies SG; Russell AJ; Sim E
    Bioorg Med Chem Lett; 2013 May; 23(9):2759-64. PubMed ID: 23518278
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mycobacterium tuberculosis lysine-ɛ-aminotransferase a potential target in dormancy: Benzothiazole based inhibitors.
    Reshma RS; Jeankumar VU; Kapoor N; Saxena S; Bobesh KA; Vachaspathy AR; Kolattukudy PE; Sriram D
    Bioorg Med Chem; 2017 May; 25(10):2761-2771. PubMed ID: 28389113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Docking- and pharmacophore-based virtual screening for the identification of novel Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitor with a thiobarbiturate scaffold.
    Zhang D; Lin Y; Chen X; Zhao W; Chen D; Gao M; Wang Q; Wang B; Huang H; Lu Y; Lu Y
    Bioorg Chem; 2019 Apr; 85():229-239. PubMed ID: 30641319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of C-5 modified 2'-deoxyuridine monophosphates as inhibitors of M. tuberculosis thymidylate synthase.
    Alexandrova LA; Chekhov VO; Shmalenyuk ER; Kochetkov SN; El-Asrar RA; Herdewijn P
    Bioorg Med Chem; 2015 Nov; 23(22):7131-7. PubMed ID: 26482569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.