BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 25544045)

  • 1. The novolactone natural product disrupts the allosteric regulation of Hsp70.
    Hassan AQ; Kirby CA; Zhou W; Schuhmann T; Kityk R; Kipp DR; Baird J; Chen J; Chen Y; Chung F; Hoepfner D; Movva NR; Pagliarini R; Petersen F; Quinn C; Quinn D; Riedl R; Schmitt EK; Schitter A; Stams T; Studer C; Fortin PD; Mayer MP; Sadlish H
    Chem Biol; 2015 Jan; 22(1):87-97. PubMed ID: 25544045
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing Allosteric Inhibition Mechanisms of the Hsp70 Chaperone Proteins Using Molecular Dynamics Simulations and Analysis of the Residue Interaction Networks.
    Stetz G; Verkhivker GM
    J Chem Inf Model; 2016 Aug; 56(8):1490-517. PubMed ID: 27447295
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hsp70 chaperone ligands control domain association via an allosteric mechanism mediated by the interdomain linker.
    Swain JF; Dinler G; Sivendran R; Montgomery DL; Stotz M; Gierasch LM
    Mol Cell; 2007 Apr; 26(1):27-39. PubMed ID: 17434124
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coordinated activation of Hsp70 chaperones.
    Steel GJ; Fullerton DM; Tyson JR; Stirling CJ
    Science; 2004 Jan; 303(5654):98-101. PubMed ID: 14704430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The four hydrophobic residues on the Hsp70 inter-domain linker have two distinct roles.
    Kumar DP; Vorvis C; Sarbeng EB; Cabra Ledesma VC; Willis JE; Liu Q
    J Mol Biol; 2011 Sep; 411(5):1099-113. PubMed ID: 21762702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40.
    Thirunavukarasu D; Shi H
    Nucleic Acid Ther; 2015 Apr; 25(2):103-12. PubMed ID: 25654640
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s.
    Yang J; Zong Y; Su J; Li H; Zhu H; Columbus L; Zhou L; Liu Q
    Nat Commun; 2017 Oct; 8(1):1201. PubMed ID: 29084938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High affinity binding between Hsp70 and the C-terminal domain of the measles virus nucleoprotein requires an Hsp40 co-chaperone.
    Couturier M; Buccellato M; Costanzo S; Bourhis JM; Shu Y; Nicaise M; Desmadril M; Flaudrops C; Longhi S; Oglesbee M
    J Mol Recognit; 2010; 23(3):301-15. PubMed ID: 19718689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resonance assignments for the substrate binding domain of Hsp70 chaperone Ssa1 from Saccharomyces cerevisiae.
    Hu W; Wu H; Zhang H; Gong W; Perrett S
    Biomol NMR Assign; 2015 Oct; 9(2):329-32. PubMed ID: 25682100
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions.
    Vembar SS; Jin Y; Brodsky JL; Hendershot LM
    J Biol Chem; 2009 Nov; 284(47):32462-71. PubMed ID: 19748898
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The membrane-bound DnaJ protein located at the cytosolic site of glyoxysomes specifically binds the cytosolic isoform 1 of Hsp70 but not other Hsp70 species.
    Diefenbach J; Kindl H
    Eur J Biochem; 2000 Feb; 267(3):746-54. PubMed ID: 10651811
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gentamicin inhibits HSP70-assisted protein folding by interfering with substrate recognition.
    Yamamoto S; Nakano S; Owari K; Fuziwara K; Ogawa N; Otaka M; Tamaki K; Watanabe S; Komatsuda A; Wakui H; Sawada K; Kubota H; Itoh H
    FEBS Lett; 2010 Feb; 584(4):645-51. PubMed ID: 20026329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The allosteric transition in DnaK probed by infrared difference spectroscopy. Concerted ATP-induced rearrangement of the substrate binding domain.
    Moro F; Fernández-Sáiz V; Muga A
    Protein Sci; 2006 Feb; 15(2):223-33. PubMed ID: 16384998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure and energetics of an allele-specific genetic interaction between dnaJ and dnaK: correlation of nuclear magnetic resonance chemical shift perturbations in the J-domain of Hsp40/DnaJ with binding affinity for the ATPase domain of Hsp70/DnaK.
    Landry SJ
    Biochemistry; 2003 May; 42(17):4926-36. PubMed ID: 12718534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Molecular mechanism of Hsp70 chaperones].
    Mayer MP; Tomoyasu T; Bukau B
    Tanpakushitsu Kakusan Koso; 2002 Jul; 47(9):1189-95. PubMed ID: 12166065
    [No Abstract]   [Full Text] [Related]  

  • 16. The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation.
    Xu L; Gong W; Cusack SA; Wu H; Loovers HM; Zhang H; Perrett S; Jones GW
    Cell Mol Life Sci; 2018 Apr; 75(8):1445-1459. PubMed ID: 29124308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.
    Stetz G; Verkhivker GM
    PLoS One; 2015; 10(11):e0143752. PubMed ID: 26619280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains.
    English CA; Sherman W; Meng W; Gierasch LM
    J Biol Chem; 2017 Sep; 292(36):14765-14774. PubMed ID: 28754691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Allosteric regulation of Hsp70 chaperones involves a conserved interdomain linker.
    Vogel M; Mayer MP; Bukau B
    J Biol Chem; 2006 Dec; 281(50):38705-11. PubMed ID: 17052976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the substrate binding domain of the Escherichia coli 70 kDa molecular chaperone, DnaK, which alter substrate affinity or interdomain coupling.
    Montgomery DL; Morimoto RI; Gierasch LM
    J Mol Biol; 1999 Feb; 286(3):915-32. PubMed ID: 10024459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.