203 related articles for article (PubMed ID: 25544756)
1. Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.
Lim CB; Prêle CM; Baltic S; Arthur PG; Creaney J; Watkins DN; Thompson PJ; Mutsaers SE
Oncotarget; 2015 Jan; 6(3):1519-30. PubMed ID: 25544756
[TBL] [Abstract][Full Text] [Related]
2. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
[TBL] [Abstract][Full Text] [Related]
3. Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells.
Valenti D; de Bari L; Manente GA; Rossi L; Mutti L; Moro L; Vacca RA
Biochim Biophys Acta; 2013 Dec; 1832(12):2085-96. PubMed ID: 23911347
[TBL] [Abstract][Full Text] [Related]
4. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
[TBL] [Abstract][Full Text] [Related]
5. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Mazumdar T; Devecchio J; Agyeman A; Shi T; Houghton JA
Cancer Res; 2011 Sep; 71(17):5904-14. PubMed ID: 21747117
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Mazumdar T; DeVecchio J; Shi T; Jones J; Agyeman A; Houghton JA
Cancer Res; 2011 Feb; 71(3):1092-102. PubMed ID: 21135115
[TBL] [Abstract][Full Text] [Related]
7. Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.
Zhang R; Wu J; Ferrandon S; Glowacki KJ; Houghton JA
Oncotarget; 2016 Dec; 7(49):80190-80207. PubMed ID: 27863397
[TBL] [Abstract][Full Text] [Related]
8. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
[TBL] [Abstract][Full Text] [Related]
9. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
[TBL] [Abstract][Full Text] [Related]
10. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
[TBL] [Abstract][Full Text] [Related]
11. Pemetrexed induces apoptosis in malignant mesothelioma and lung cancer cells through activation of reactive oxygen species and inhibition of sirtuin 1.
Hwang KE; Kim YS; Hwang YR; Kwon SJ; Park DS; Cha BK; Kim BR; Yoon KH; Jeong ET; Kim HR
Oncol Rep; 2015 May; 33(5):2411-9. PubMed ID: 25738249
[TBL] [Abstract][Full Text] [Related]
12. Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.
Meister MT; Boedicker C; Linder B; Kögel D; Klingebiel T; Fulda S
Cancer Lett; 2019 Nov; 465():1-11. PubMed ID: 31465840
[TBL] [Abstract][Full Text] [Related]
13. Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.
Huang L; Walter V; Hayes DN; Onaitis M
Clin Cancer Res; 2014 Mar; 20(6):1566-75. PubMed ID: 24423612
[TBL] [Abstract][Full Text] [Related]
14. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
Graab U; Hahn H; Fulda S
Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
[TBL] [Abstract][Full Text] [Related]
15. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells.
Matsumoto T; Tabata K; Suzuki T
Biol Pharm Bull; 2014; 37(4):633-41. PubMed ID: 24694609
[TBL] [Abstract][Full Text] [Related]
16. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling.
Harada K; Ohashi R; Naito K; Kanki K
Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32354204
[TBL] [Abstract][Full Text] [Related]
17. GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells.
Bacelar Sacramento de Araújo T; de Oliveira Siquara da Rocha L; Torres Andion Vidal M; Cerqueira Coelho PL; Galvão Dos Reis M; Solano de Freitas Souza B; Botelho Pereira Soares M; Almeida Pereira T; Della Coletta R; Pereira Bezerra D; Borges Dias R; Araújo Gurgel Rocha C
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846867
[TBL] [Abstract][Full Text] [Related]
18. Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.
Masetti R; Bertuccio SN; Astolfi A; Chiarini F; Lonetti A; Indio V; De Luca M; Bandini J; Serravalle S; Franzoni M; Pigazzi M; Martelli AM; Basso G; Locatelli F; Pession A
J Hematol Oncol; 2017 Jan; 10(1):26. PubMed ID: 28109323
[TBL] [Abstract][Full Text] [Related]
19. Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
Agyeman A; Jha BK; Mazumdar T; Houghton JA
Oncotarget; 2014 Jun; 5(12):4492-503. PubMed ID: 24962990
[TBL] [Abstract][Full Text] [Related]
20. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
