BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 25546301)

  • 1. Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
    Kong L; Wilson IA; Kwong PD
    Proteins; 2015 Mar; 83(3):590-6. PubMed ID: 25546301
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
    Pejchal R; Doores KJ; Walker LM; Khayat R; Huang PS; Wang SK; Stanfield RL; Julien JP; Ramos A; Crispin M; Depetris R; Katpally U; Marozsan A; Cupo A; Maloveste S; Liu Y; McBride R; Ito Y; Sanders RW; Ogohara C; Paulson JC; Feizi T; Scanlan CN; Wong CH; Moore JP; Olson WC; Ward AB; Poignard P; Schief WR; Burton DR; Wilson IA
    Science; 2011 Nov; 334(6059):1097-103. PubMed ID: 21998254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity.
    Rathore U; Saha P; Kesavardhana S; Kumar AA; Datta R; Devanarayanan S; Das R; Mascola JR; Varadarajan R
    J Biol Chem; 2017 Jun; 292(24):10197-10219. PubMed ID: 28446609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
    Kong L; Lee JH; Doores KJ; Murin CD; Julien JP; McBride R; Liu Y; Marozsan A; Cupo A; Klasse PJ; Hoffenberg S; Caulfield M; King CR; Hua Y; Le KM; Khayat R; Deller MC; Clayton T; Tien H; Feizi T; Sanders RW; Paulson JC; Moore JP; Stanfield RL; Burton DR; Ward AB; Wilson IA
    Nat Struct Mol Biol; 2013 Jul; 20(7):796-803. PubMed ID: 23708606
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
    Gorman J; Mason RD; Nettey L; Cavett N; Chuang GY; Peng D; Tsybovsky Y; Verardi R; Nguyen R; Ambrozak D; Biris K; LaBranche CC; Ramesh A; Schramm CA; Zhou J; Bailer RT; Kepler TB; Montefiori DC; Shapiro L; Douek DC; Mascola JR; Roederer M; Kwong PD
    Immunity; 2019 Oct; 51(4):724-734.e4. PubMed ID: 31586542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The glycan-mediated mechanism on the interactions of gp120 with CD4 and antibody: Insights from molecular dynamics simulation.
    Zhang Y; Niu Y; Tian J; Liu X; Yao X; Liu H
    Chem Biol Drug Des; 2017 Dec; 90(6):1237-1246. PubMed ID: 28632942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
    Bonomelli C; Doores KJ; Dunlop DC; Thaney V; Dwek RA; Burton DR; Crispin M; Scanlan CN
    PLoS One; 2011; 6(8):e23521. PubMed ID: 21858152
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
    Kong L; Torrents de la Peña A; Deller MC; Garces F; Sliepen K; Hua Y; Stanfield RL; Sanders RW; Wilson IA
    Acta Crystallogr D Biol Crystallogr; 2015 Oct; 71(Pt 10):2099-108. PubMed ID: 26457433
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies.
    Ingale J; Tran K; Kong L; Dey B; McKee K; Schief W; Kwong PD; Mascola JR; Wyatt RT
    J Virol; 2014 Dec; 88(24):14002-16. PubMed ID: 25253346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual.
    Coss KP; Vasiljevic S; Pritchard LK; Krumm SA; Glaze M; Madzorera S; Moore PL; Crispin M; Doores KJ
    J Virol; 2016 Dec; 90(24):11132-11144. PubMed ID: 27707925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
    Gristick HB; von Boehmer L; West AP; Schamber M; Gazumyan A; Golijanin J; Seaman MS; Fätkenheuer G; Klein F; Nussenzweig MC; Bjorkman PJ
    Nat Struct Mol Biol; 2016 Oct; 23(10):906-915. PubMed ID: 27617431
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site.
    Wibmer CK; Gorman J; Anthony CS; Mkhize NN; Druz A; York T; Schmidt SD; Labuschagne P; Louder MK; Bailer RT; Abdool Karim SS; Mascola JR; Williamson C; Moore PL; Kwong PD; Morris L
    J Virol; 2016 Nov; 90(22):10220-10235. PubMed ID: 27581986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational Heterogeneity of the HIV Envelope Glycan Shield.
    Yang M; Huang J; Simon R; Wang LX; MacKerell AD
    Sci Rep; 2017 Jun; 7(1):4435. PubMed ID: 28667249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.
    Doores KJ; Bonomelli C; Harvey DJ; Vasiljevic S; Dwek RA; Burton DR; Crispin M; Scanlan CN
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13800-5. PubMed ID: 20643940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The highly conserved glycan at asparagine 260 of HIV-1 gp120 is indispensable for viral entry.
    François KO; Balzarini J
    J Biol Chem; 2011 Dec; 286(50):42900-10. PubMed ID: 22006924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycan Profiles of gp120 Protein Vaccines from Four Major HIV-1 Subtypes Produced from Different Host Cell Lines under Non-GMP or GMP Conditions.
    Wang S; Voronin Y; Zhao P; Ishihara M; Mehta N; Porterfield M; Chen Y; Bartley C; Hu G; Han D; Wells L; Tiemeyer M; Lu S
    J Virol; 2020 Mar; 94(7):. PubMed ID: 31941770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
    Julien JP; Sok D; Khayat R; Lee JH; Doores KJ; Walker LM; Ramos A; Diwanji DC; Pejchal R; Cupo A; Katpally U; Depetris RS; Stanfield RL; McBride R; Marozsan AJ; Paulson JC; Sanders RW; Moore JP; Burton DR; Poignard P; Ward AB; Wilson IA
    PLoS Pathog; 2013; 9(5):e1003342. PubMed ID: 23658524
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic labeling of HIV-1 envelope glycoprotein gp120 to elucidate the effect of gp120 glycosylation on antigen uptake.
    Sun L; Ishihara M; Middleton DR; Tiemeyer M; Avci FY
    J Biol Chem; 2018 Sep; 293(39):15178-15194. PubMed ID: 30115684
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.
    Koch M; Pancera M; Kwong PD; Kolchinsky P; Grundner C; Wang L; Hendrickson WA; Sodroski J; Wyatt R
    Virology; 2003 Sep; 313(2):387-400. PubMed ID: 12954207
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.
    Sanders RW; van Anken E; Nabatov AA; Liscaljet IM; Bontjer I; Eggink D; Melchers M; Busser E; Dankers MM; Groot F; Braakman I; Berkhout B; Paxton WA
    Retrovirology; 2008 Jan; 5():10. PubMed ID: 18237398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.