These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 25555107)

  • 1. The activating oxydianion binding domain for enzyme-catalyzed proton transfer, hydride transfer, and decarboxylation: specificity and enzyme architecture.
    Reyes AC; Zhai X; Morgan KT; Reinhardt CJ; Amyes TL; Richard JP
    J Am Chem Soc; 2015 Jan; 137(3):1372-82. PubMed ID: 25555107
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzyme architecture: the activating oxydianion binding domain for orotidine 5'-monophophate decarboxylase.
    Spong K; Amyes TL; Richard JP
    J Am Chem Soc; 2013 Dec; 135(49):18343-6. PubMed ID: 24274746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specificity in transition state binding: the Pauling model revisited.
    Amyes TL; Richard JP
    Biochemistry; 2013 Mar; 52(12):2021-35. PubMed ID: 23327224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization.
    Goryanova B; Amyes TL; Richard JP
    J Am Chem Soc; 2019 Aug; 141(34):13468-13478. PubMed ID: 31365243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzyme Architecture: Erection of Active Orotidine 5'-Monophosphate Decarboxylase by Substrate-Induced Conformational Changes.
    Reyes AC; Amyes TL; Richard JP
    J Am Chem Soc; 2017 Nov; 139(45):16048-16051. PubMed ID: 29058891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions.
    Goryanova B; Goldman LM; Amyes TL; Gerlt JA; Richard JP
    Biochemistry; 2013 Oct; 52(42):7500-11. PubMed ID: 24053466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.
    Tsang WY; Wood BM; Wong FM; Wu W; Gerlt JA; Amyes TL; Richard JP
    J Am Chem Soc; 2012 Sep; 134(35):14580-94. PubMed ID: 22812629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate Decarboxylase.
    Goryanova B; Goldman LM; Ming S; Amyes TL; Gerlt JA; Richard JP
    Biochemistry; 2015 Jul; 54(29):4555-64. PubMed ID: 26135041
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.
    Goryanova B; Spong K; Amyes TL; Richard JP
    Biochemistry; 2013 Jan; 52(3):537-46. PubMed ID: 23276261
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organisms.
    Toth K; Amyes TL; Wood BM; Chan KK; Gerlt JA; Richard JP
    Biochemistry; 2009 Aug; 48(33):8006-13. PubMed ID: 19618917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Orotidine 5'-Monophosphate Decarboxylase: Probing the Limits of the Possible for Enzyme Catalysis.
    Richard JP; Amyes TL; Reyes AC
    Acc Chem Res; 2018 Apr; 51(4):960-969. PubMed ID: 29595949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzyme Architecture: Self-Assembly of Enzyme and Substrate Pieces of Glycerol-3-Phosphate Dehydrogenase into a Robust Catalyst of Hydride Transfer.
    Reyes AC; Amyes TL; Richard JP
    J Am Chem Soc; 2016 Nov; 138(46):15251-15259. PubMed ID: 27792325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enzyme architecture: deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5'-monophosphate decarboxylase.
    Goldman LM; Amyes TL; Goryanova B; Gerlt JA; Richard JP
    J Am Chem Soc; 2014 Jul; 136(28):10156-65. PubMed ID: 24958125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5'-Monophosphate Decarboxylase for Catalysis.
    Reyes AC; Plache DC; Koudelka AP; Amyes TL; Gerlt JA; Richard JP
    J Am Chem Soc; 2018 Dec; 140(50):17580-17590. PubMed ID: 30475611
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetics and mechanism for enzyme-catalyzed reactions of substrate pieces.
    Cristobal JR; Richard JP
    Methods Enzymol; 2023; 685():95-126. PubMed ID: 37245916
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein-Ribofuranosyl Interactions Activate Orotidine 5'-Monophosphate Decarboxylase for Catalysis.
    Cristobal JR; Brandão TAS; Reyes AC; Richard JP
    Biochemistry; 2021 Nov; 60(45):3362-3373. PubMed ID: 34726391
    [TBL] [Abstract][Full Text] [Related]  

  • 17. OMP decarboxylase: phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate.
    Goryanova B; Amyes TL; Gerlt JA; Richard JP
    J Am Chem Soc; 2011 May; 133(17):6545-8. PubMed ID: 21486036
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphate binding energy and catalysis by small and large molecules.
    Morrow JR; Amyes TL; Richard JP
    Acc Chem Res; 2008 Apr; 41(4):539-48. PubMed ID: 18293941
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies.
    Mydy LS; Cristobal JR; Katigbak RD; Bauer P; Reyes AC; Kamerlin SCL; Richard JP; Gulick AM
    Biochemistry; 2019 Feb; 58(8):1061-1073. PubMed ID: 30640445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Orotidine 5'-monophosphate decarboxylase: transition state stabilization from remote protein-phosphodianion interactions.
    Amyes TL; Ming SA; Goldman LM; Wood BM; Desai BJ; Gerlt JA; Richard JP
    Biochemistry; 2012 Jun; 51(23):4630-2. PubMed ID: 22620855
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.