BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 25562686)

  • 1. The selective activation of p53 target genes regulated by SMYD2 in BIX-01294 induced autophagy-related cell death.
    Fan JD; Lei PJ; Zheng JY; Wang X; Li S; Liu H; He YL; Wang ZN; Wei G; Zhang X; Li LY; Wu M
    PLoS One; 2015; 10(1):e0116782. PubMed ID: 25562686
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.
    Kim Y; Kim YS; Kim DE; Lee JS; Song JH; Kim HG; Cho DH; Jeong SY; Jin DH; Jang SJ; Seol HS; Suh YA; Lee SJ; Kim CS; Koh JY; Hwang JJ
    Autophagy; 2013 Dec; 9(12):2126-39. PubMed ID: 24322755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G9a inhibition induced PKM2 regulates autophagic responses.
    Ahmad F; Dixit D; Joshi SD; Sen E
    Int J Biochem Cell Biol; 2016 Sep; 78():87-95. PubMed ID: 27417236
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma.
    Ren A; Qiu Y; Cui H; Fu G
    Biochem Biophys Res Commun; 2015 Mar; 459(1):10-7. PubMed ID: 25634693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
    Park KE; Johnson CM; Cabot RA
    Reprod Fertil Dev; 2012; 24(6):813-21. PubMed ID: 22781932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Repression of p53 activity by Smyd2-mediated methylation.
    Huang J; Perez-Burgos L; Placek BJ; Sengupta R; Richter M; Dorsey JA; Kubicek S; Opravil S; Jenuwein T; Berger SL
    Nature; 2006 Nov; 444(7119):629-32. PubMed ID: 17108971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos.
    Huang Y; Jiang X; Yu M; Huang R; Yao J; Li M; Zheng F; Yang X
    Reprod Fertil Dev; 2017 Jun; 29(6):1260-1269. PubMed ID: 27477633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BIX-01294-induced autophagy regulates elongation of primary cilia.
    Shin JH; Kim PS; Kim ES; Park SJ; Jo YK; Hwang JJ; Park TJ; Chang JW; Seo JH; Cho DH
    Biochem Biophys Res Commun; 2015 May; 460(2):428-33. PubMed ID: 25796328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of BIX-01294 on proliferation, apoptosis and histone methylation of acute T lymphoblastic leukemia cells.
    Huang Y; Zou Y; Lin L; Ma X; Huang X
    Leuk Res; 2017 Nov; 62():34-39. PubMed ID: 28982057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein.
    Hwang S; Kim S; Kim K; Yeom J; Park S; Kim I
    BMB Rep; 2020 Nov; 53(11):576-581. PubMed ID: 32684241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line.
    Huang SW; Chang SH; Mu SW; Jiang HY; Wang ST; Kao JK; Huang JL; Wu CY; Chen YJ; Shieh JJ
    J Dermatol Sci; 2016 Mar; 81(3):182-91. PubMed ID: 26775629
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylation-acetylation interplay activates p53 in response to DNA damage.
    Ivanov GS; Ivanova T; Kurash J; Ivanov A; Chuikov S; Gizatullin F; Herrera-Medina EM; Rauscher F; Reinberg D; Barlev NA
    Mol Cell Biol; 2007 Oct; 27(19):6756-69. PubMed ID: 17646389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heme oxygenase-1-mediated apoptosis under cadmium-induced oxidative stress is regulated by autophagy, which is sensitized by tumor suppressor p53.
    So KY; Oh SH
    Biochem Biophys Res Commun; 2016 Oct; 479(1):80-5. PubMed ID: 27620489
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
    Lu Z; Tian Y; Salwen HR; Chlenski A; Godley LA; Raj JU; Yang Q
    Anticancer Drugs; 2013 Jun; 24(5):484-93. PubMed ID: 23466651
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells.
    Ciechomska IA; Przanowski P; Jackl J; Wojtas B; Kaminska B
    Sci Rep; 2016 Dec; 6():38723. PubMed ID: 27934912
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells.
    Li Q; Wang L; Ji D; Bao X; Tan G; Liang X; Deng P; Pi H; Lu Y; Chen C; He M; Zhang L; Zhou Z; Yu Z; Deng A
    Invest New Drugs; 2021 Jun; 39(3):686-696. PubMed ID: 33387131
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of BIX-01294 on H3K9me2 levels and the imprinted gene Snrpn in mouse embryonic fibroblast cells.
    Chen P; Yao JF; Huang RF; Zheng FF; Jiang XH; Chen X; Chen J; Li M; Huang HF; Jiang YP; Huang YF; Yang XY
    Biosci Rep; 2015 Aug; 35(5):. PubMed ID: 26285804
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protopine isolated from Nandina domestica induces apoptosis and autophagy in colon cancer cells by stabilizing p53.
    Son Y; An Y; Jung J; Shin S; Park I; Gwak J; Ju BG; Chung YH; Na M; Oh S
    Phytother Res; 2019 Jun; 33(6):1689-1696. PubMed ID: 30932278
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway.
    Ho JC; Abdullah LN; Pang QY; Jha S; Chow EK; Yang H; Kato H; Poellinger L; Ueda J; Lee KL
    PLoS One; 2017; 12(11):e0188051. PubMed ID: 29145444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ASPP2 enhances oxaliplatin (L-OHP)-induced colorectal cancer cell apoptosis in a p53-independent manner by inhibiting cell autophagy.
    Shi Y; Han Y; Xie F; Wang A; Feng X; Li N; Guo H; Chen D
    J Cell Mol Med; 2015 Mar; 19(3):535-43. PubMed ID: 25534115
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.