214 related articles for article (PubMed ID: 25578243)
1. Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity.
Gee RH; Spinks JN; Malia JM; Johnston JD; Plant NJ; Plant KE
Toxicology; 2015 Mar; 329():40-8. PubMed ID: 25578243
[TBL] [Abstract][Full Text] [Related]
2. Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone.
Johnson TE; Zhang X; Bleicher KB; Dysart G; Loughlin AF; Schaefer WH; Umbenhauer DR
Toxicol Appl Pharmacol; 2004 Nov; 200(3):237-50. PubMed ID: 15504460
[TBL] [Abstract][Full Text] [Related]
3. Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.
Mullen PJ; Lüscher B; Scharnagl H; Krähenbühl S; Brecht K
Biochem Pharmacol; 2010 Apr; 79(8):1200-9. PubMed ID: 20018177
[TBL] [Abstract][Full Text] [Related]
4. Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.
Nishimoto T; Ishikawa E; Anayama H; Hamajyo H; Nagai H; Hirakata M; Tozawa R
Toxicol Appl Pharmacol; 2007 Aug; 223(1):39-45. PubMed ID: 17599378
[TBL] [Abstract][Full Text] [Related]
5. Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure.
Jalal MM; Whyte CS; Coxon FP; Mutch NJ
Platelets; 2023 Dec; 34(1):2206921. PubMed ID: 37139869
[TBL] [Abstract][Full Text] [Related]
6. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
Gbelcová H; Rimpelová S; Knejzlík Z; Šáchová J; Kolář M; Strnad H; Repiská V; D'Acunto WC; Ruml T; Vítek L
Lipids Health Dis; 2017 Dec; 16(1):250. PubMed ID: 29262834
[TBL] [Abstract][Full Text] [Related]
7. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells.
Sidaway JE; Davidson RG; McTaggart F; Orton TC; Scott RC; Smith GJ; Brunskill NJ
J Am Soc Nephrol; 2004 Sep; 15(9):2258-65. PubMed ID: 15339975
[TBL] [Abstract][Full Text] [Related]
8. Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.
Osaki Y; Nakagawa Y; Miyahara S; Iwasaki H; Ishii A; Matsuzaka T; Kobayashi K; Yatoh S; Takahashi A; Yahagi N; Suzuki H; Sone H; Ohashi K; Ishibashi S; Yamada N; Shimano H
Biochem Biophys Res Commun; 2015 Oct; 466(3):536-40. PubMed ID: 26381177
[TBL] [Abstract][Full Text] [Related]
9. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation.
Wong B; Lumma WC; Smith AM; Sisko JT; Wright SD; Cai TQ
J Leukoc Biol; 2001 Jun; 69(6):959-62. PubMed ID: 11404382
[TBL] [Abstract][Full Text] [Related]
10. Modulation of COX-2 expression by statins in human monocytic cells.
Habib A; Shamseddeen I; Nasrallah MS; Antoun TA; Nemer G; Bertoglio J; Badreddine R; Badr KF
FASEB J; 2007 Jun; 21(8):1665-74. PubMed ID: 17317725
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines.
Ageberg M; Rydström K; Lindén O; Linderoth J; Jerkeman M; Drott K
Exp Cell Res; 2011 May; 317(8):1179-91. PubMed ID: 21324313
[TBL] [Abstract][Full Text] [Related]
12. Influence of HMG-CoA reductase inhibitors on leptin-induced endothelial cell proliferation, migration, and capillary-like tube formation.
Burgazli KM; Stein NI; Mericliler M; Parahuleva M; Erdogan A
Postgrad Med; 2014 May; 126(3):231-8. PubMed ID: 24918807
[TBL] [Abstract][Full Text] [Related]
13. Molecular clues into the pathogenesis of statin-mediated muscle toxicity.
Baker SK
Muscle Nerve; 2005 May; 31(5):572-80. PubMed ID: 15712281
[TBL] [Abstract][Full Text] [Related]
14. Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
Alizadeh J; Zeki AA; Mirzaei N; Tewary S; Rezaei Moghadam A; Glogowska A; Nagakannan P; Eftekharpour E; Wiechec E; Gordon JW; Xu FY; Field JT; Yoneda KY; Kenyon NJ; Hashemi M; Hatch GM; Hombach-Klonisch S; Klonisch T; Ghavami S
Sci Rep; 2017 Mar; 7():44841. PubMed ID: 28344327
[TBL] [Abstract][Full Text] [Related]
15. Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Kah J; Wüstenberg A; Keller AD; Sirma H; Montalbano R; Ocker M; Volz T; Dandri M; Tiegs G; Sass G
Oncol Rep; 2012 Sep; 28(3):1077-83. PubMed ID: 22710979
[TBL] [Abstract][Full Text] [Related]
16. The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle.
Schaafsma D; Dueck G; Ghavami S; Kroeker A; Mutawe MM; Hauff K; Xu FY; McNeill KD; Unruh H; Hatch GM; Halayko AJ
Am J Respir Cell Mol Biol; 2011 Mar; 44(3):394-403. PubMed ID: 20463291
[TBL] [Abstract][Full Text] [Related]
17. Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin.
Takeda N; Kondo M; Ito S; Ito Y; Shimokata K; Kume H
Am J Respir Cell Mol Biol; 2006 Dec; 35(6):722-9. PubMed ID: 16858009
[TBL] [Abstract][Full Text] [Related]
18. HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.
Al-Haidari AA; Syk I; Thorlacius H
Biochem Biophys Res Commun; 2014 Mar; 446(1):68-72. PubMed ID: 24582560
[TBL] [Abstract][Full Text] [Related]
19. The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.
Staal A; Frith JC; French MH; Swartz J; Güngör T; Harrity TW; Tamasi J; Rogers MJ; Feyen JH
J Bone Miner Res; 2003 Jan; 18(1):88-96. PubMed ID: 12510809
[TBL] [Abstract][Full Text] [Related]
20. Effects of HMG-CoA reductase inhibitors on skeletal muscle: are all statins the same?
Evans M; Rees A
Drug Saf; 2002; 25(9):649-63. PubMed ID: 12137559
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]