BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 25579572)

  • 1. Design and virtual screening towards synthesis of novel substituted thiosemicarbozones as ribonuleotide reductase (RNR) inhibitors with improved cellular trafficking and anticancer activity.
    Gokhale N; Jain S; Yadav M
    Curr Top Med Chem; 2015; 15(1):37-42. PubMed ID: 25579572
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling and Proposed Molecular Mechanism of Hydroxyurea Through Docking and Molecular Dynamic Simulation to Curtail the Action of Ribonucleotide Reductase.
    Iman M; Khansefid Z; Davood A
    Recent Pat Anticancer Drug Discov; 2016; 11(4):461-468. PubMed ID: 27670694
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New Iminodiacetate-Thiosemicarbazone Hybrids and Their Copper(II) Complexes Are Potential Ribonucleotide Reductase R2 Inhibitors with High Antiproliferative Activity.
    Zaltariov MF; Hammerstad M; Arabshahi HJ; Jovanović K; Richter KW; Cazacu M; Shova S; Balan M; Andersen NH; Radulović S; Reynisson J; Andersson KK; Arion VB
    Inorg Chem; 2017 Mar; 56(6):3532-3549. PubMed ID: 28252952
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent ribonucleotide reductase inhibitors: Thiazole-containing thiosemicarbazone derivatives.
    Ertas M; Sahin Z; Bulbul EF; Bender C; Biltekin SN; Berk B; Yurttas L; Nalbur AM; Celik H; Demirayak Ş
    Arch Pharm (Weinheim); 2019 Nov; 352(11):e1900033. PubMed ID: 31475759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Syntheses and antitumor activities of potent inhibitors of ribonucleotide reductase: 3-amino-4-methylpyridine-2-carboxaldehyde-thiosemicarba-zone (3-AMP), 3-amino-pyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) and its water-soluble prodrugs.
    Li J; Zheng LM; King I; Doyle TW; Chen SH
    Curr Med Chem; 2001 Feb; 8(2):121-33. PubMed ID: 11172670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activity and electrochemical properties: iron complexes of the anticancer drug triapine and its analogs.
    Plamthottam S; Sun D; Van Valkenburgh J; Valenzuela J; Ruehle B; Steele D; Poddar S; Marshalik M; Hernandez S; Radu CG; Zink JI
    J Biol Inorg Chem; 2019 Aug; 24(5):621-632. PubMed ID: 31250199
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.
    Popović-Bijelić A; Kowol CR; Lind ME; Luo J; Himo F; Enyedy EA; Arion VB; Gräslund A
    J Inorg Biochem; 2011 Nov; 105(11):1422-31. PubMed ID: 21955844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of ribonucleotide reductase inhibitors: a review on structure activity relationships.
    Moorthy NS; Cerqueira NM; Ramos MJ; Fernandes PA
    Mini Rev Med Chem; 2013 Nov; 13(13):1862-72. PubMed ID: 24032510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance.
    Zhou B; Su L; Hu S; Hu W; Yip ML; Wu J; Gaur S; Smith DL; Yuan YC; Synold TW; Horne D; Yen Y
    Cancer Res; 2013 Nov; 73(21):6484-93. PubMed ID: 24072748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ribonucleotide reductase inhibition by p-alkoxyphenols studied by molecular docking and molecular dynamics simulations.
    Luo J; Gräslund A
    Arch Biochem Biophys; 2011 Dec; 516(1):29-34. PubMed ID: 21951815
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ribonucleotide reductase inhibitors as anti-herpes agents.
    Wnuk SF; Robins MJ
    Antiviral Res; 2006 Sep; 71(2-3):122-6. PubMed ID: 16621038
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and ribonucleotide reductase inhibitory activity of thiosemicarbazones.
    Krishnan K; Prathiba K; Jayaprakash V; Basu A; Mishra N; Zhou B; Hu S; Yen Y
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6248-50. PubMed ID: 18976907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format.
    Tholander F; Sjöberg BM
    Proc Natl Acad Sci U S A; 2012 Jun; 109(25):9798-803. PubMed ID: 22665797
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computer-aided drug design and virtual screening of targeted combinatorial libraries of mixed-ligand transition metal complexes of 2-butanone thiosemicarbazone.
    Khan T; Ahmad R; Azad I; Raza S; Joshi S; Khan AR
    Comput Biol Chem; 2018 Aug; 75():178-195. PubMed ID: 29883916
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, Synthesis, Cytotoxic Screening and Molecular Docking Studies of Novel Hybrid Thiosemicarbazone Derivatives as Anticancer Agents.
    Mohammed FZ; Rizzk YW; El Deen IM; Mourad AAE; El Behery M
    Chem Biodivers; 2021 Dec; 18(12):e2100580. PubMed ID: 34699127
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, cytotoxic evaluation, docking and in silico pharmacokinetic prediction of 4-arylideneamino/cycloalkylidineamino 1, 2-naphthoquinone thiosemicarbazones.
    Shukla S; Srivastava RS; Shrivastava SK; Sodhi A; Kumar P
    J Enzyme Inhib Med Chem; 2013 Dec; 28(6):1192-8. PubMed ID: 22978426
    [TBL] [Abstract][Full Text] [Related]  

  • 18. alpha-N-heterocyclic thiosemicarbazone derivatives as potential antitumor agents: a structure-activity relationships approach.
    Matesanz AI; Souza P
    Mini Rev Med Chem; 2009 Oct; 9(12):1389-96. PubMed ID: 19929812
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel glyoxalase-I inhibitors possessing a "zinc-binding feature" as potential anticancer agents.
    Al-Balas QA; Hassan MA; Al-Shar'i NA; Mhaidat NM; Almaaytah AM; Al-Mahasneh FM; Isawi IH
    Drug Des Devel Ther; 2016; 10():2623-9. PubMed ID: 27574401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phototriggerable peptidomimetics for the inhibition of Mycobacterium tuberculosis ribonucleotide reductase by targeting protein-protein binding.
    Karlsson C; Blom M; Johansson M; Jansson AM; Scifo E; Karlén A; Govender T; Gogoll A
    Org Biomol Chem; 2015 Mar; 13(9):2612-21. PubMed ID: 25580895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.