639 related articles for article (PubMed ID: 25579745)
21. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
Balboa D; Saarimäki-Vire J; Borshagovski D; Survila M; Lindholm P; Galli E; Eurola S; Ustinov J; Grym H; Huopio H; Partanen J; Wartiovaara K; Otonkoski T
Elife; 2018 Nov; 7():. PubMed ID: 30412052
[TBL] [Abstract][Full Text] [Related]
22. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.
Hartley T; Siva M; Lai E; Teodoro T; Zhang L; Volchuk A
BMC Cell Biol; 2010 Jul; 11():59. PubMed ID: 20659334
[TBL] [Abstract][Full Text] [Related]
23. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
Cunningham CN; He K; Arunagiri A; Paton AW; Paton JC; Arvan P; Tsai B
Diabetes; 2017 Mar; 66(3):741-753. PubMed ID: 28028074
[TBL] [Abstract][Full Text] [Related]
24. In vivo misfolding of proinsulin below the threshold of frank diabetes.
Hodish I; Absood A; Liu L; Liu M; Haataja L; Larkin D; Al-Khafaji A; Zaki A; Arvan P
Diabetes; 2011 Aug; 60(8):2092-101. PubMed ID: 21677281
[TBL] [Abstract][Full Text] [Related]
25. Improvement of ER stress-induced diabetes by stimulating autophagy.
Bachar-Wikstrom E; Wikstrom JD; Kaiser N; Cerasi E; Leibowitz G
Autophagy; 2013 Apr; 9(4):626-8. PubMed ID: 23380813
[TBL] [Abstract][Full Text] [Related]
26. Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes.
Bachar-Wikstrom E; Wikstrom JD; Ariav Y; Tirosh B; Kaiser N; Cerasi E; Leibowitz G
Diabetes; 2013 Apr; 62(4):1227-37. PubMed ID: 23274896
[TBL] [Abstract][Full Text] [Related]
27. Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
Tran DT; Pottekat A; Mir SA; Loguercio S; Jang I; Campos AR; Scully KM; Lahmy R; Liu M; Arvan P; Balch WE; Kaufman RJ; Itkin-Ansari P
Diabetes; 2020 Aug; 69(8):1723-1734. PubMed ID: 32457219
[TBL] [Abstract][Full Text] [Related]
28. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.
Tiwari A; Schuiki I; Zhang L; Allister EM; Wheeler MB; Volchuk A
J Cell Sci; 2013 May; 126(Pt 9):1962-8. PubMed ID: 23444373
[TBL] [Abstract][Full Text] [Related]
29. Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation.
Dhayalan B; Glidden MD; Zaykov AN; Chen YS; Yang Y; Phillips NB; Ismail-Beigi F; Jarosinski MA; DiMarchi RD; Weiss MA
Front Endocrinol (Lausanne); 2022; 13():821069. PubMed ID: 35299972
[TBL] [Abstract][Full Text] [Related]
30. The ER transmembrane protein PGRMC1 recruits misfolded proteins for reticulophagic clearance.
Knupp J; Chen YJ; Arunagiri A; Haataja L; Arvan P; Tsai B
Autophagy; 2022 Jan; 18(1):228-230. PubMed ID: 34779709
[TBL] [Abstract][Full Text] [Related]
31. Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding? Kinetic simulations of extension limits and consequences on proinsulin synthesis.
Despa F
Biophys Chem; 2009 Mar; 140(1-3):115-21. PubMed ID: 19121888
[TBL] [Abstract][Full Text] [Related]
32. Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.
Park SY; Ye H; Steiner DF; Bell GI
Biochem Biophys Res Commun; 2010 Jan; 391(3):1449-54. PubMed ID: 20034470
[TBL] [Abstract][Full Text] [Related]
33. Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
Ghiasi SM; Dahlby T; Hede Andersen C; Haataja L; Petersen S; Omar-Hmeadi M; Yang M; Pihl C; Bresson SE; Khilji MS; Klindt K; Cheta O; Perone MJ; Tyrberg B; Prats C; Barg S; Tengholm A; Arvan P; Mandrup-Poulsen T; Marzec MT
Diabetes; 2019 Apr; 68(4):747-760. PubMed ID: 30670477
[TBL] [Abstract][Full Text] [Related]
34. The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets.
Khilji MS; Bresson SE; Verstappen D; Pihl C; Andersen PAK; Agergaard JB; Dahlby T; Bryde TH; Klindt K; Nielsen CK; Walentinsson A; Zivkovic D; Bousquet MP; Tyrberg B; Richardson SJ; Morgan NG; Mandrup-Poulsen T; Marzec MT
Am J Physiol Endocrinol Metab; 2020 Jun; 318(6):E892-E900. PubMed ID: 32255680
[TBL] [Abstract][Full Text] [Related]
35. Biophysical alteration of the secretory track in β-cells due to molecular overcrowding: the relevance for diabetes.
Ionescu-Tirgoviste C; Despa F
Integr Biol (Camb); 2011 Mar; 3(3):173-9. PubMed ID: 21180710
[TBL] [Abstract][Full Text] [Related]
36. Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes.
Ninagawa S; Tada S; Okumura M; Inoguchi K; Kinoshita M; Kanemura S; Imami K; Umezawa H; Ishikawa T; Mackin RB; Torii S; Ishihama Y; Inaba K; Anazawa T; Nagamine T; Mori K
Elife; 2020 Nov; 9():. PubMed ID: 33198886
[TBL] [Abstract][Full Text] [Related]
37. Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence.
Shrestha N; De Franco E; Arvan P; Cnop M
Front Endocrinol (Lausanne); 2021; 12():650158. PubMed ID: 33967960
[TBL] [Abstract][Full Text] [Related]
38. Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention.
Meur G; Simon A; Harun N; Virally M; Dechaume A; Bonnefond A; Fetita S; Tarasov AI; Guillausseau PJ; Boesgaard TW; Pedersen O; Hansen T; Polak M; Gautier JF; Froguel P; Rutter GA; Vaxillaire M
Diabetes; 2010 Mar; 59(3):653-61. PubMed ID: 20007936
[TBL] [Abstract][Full Text] [Related]
39. Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus.
Yong J; Johnson JD; Arvan P; Han J; Kaufman RJ
Nat Rev Endocrinol; 2021 Aug; 17(8):455-467. PubMed ID: 34163039
[TBL] [Abstract][Full Text] [Related]
40. Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells.
Sharma RB; Landa-Galván HV; Alonso LC
Diabetes; 2021 Nov; 70(11):2431-2443. PubMed ID: 34711668
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
