BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1192 related articles for article (PubMed ID: 25579834)

  • 1. Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials.
    ; Fulcher J; O'Connell R; Voysey M; Emberson J; Blackwell L; Mihaylova B; Simes J; Collins R; Kirby A; Colhoun H; Braunwald E; La Rosa J; Pedersen TR; Tonkin A; Davis B; Sleight P; Franzosi MG; Baigent C; Keech A
    Lancet; 2015 Apr; 385(9976):1397-405. PubMed ID: 25579834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.
    ; Baigent C; Blackwell L; Emberson J; Holland LE; Reith C; Bhala N; Peto R; Barnes EH; Keech A; Simes J; Collins R
    Lancet; 2010 Nov; 376(9753):1670-81. PubMed ID: 21067804
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials.
    ; Mihaylova B; Emberson J; Blackwell L; Keech A; Simes J; Barnes EH; Voysey M; Gray A; Collins R; Baigent C
    Lancet; 2012 Aug; 380(9841):581-90. PubMed ID: 22607822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials.
    Cholesterol Treatment Trialists' Collaboration
    Lancet; 2019 Feb; 393(10170):407-415. PubMed ID: 30712900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials.
    ; Herrington WG; Emberson J; Mihaylova B; Blackwell L; Reith C; Solbu MD; Mark PB; Fellström B; Jardine AG; Wanner C; Holdaas H; Fulcher J; Haynes R; Landray MJ; Keech A; Simes J; Collins R; Baigent C
    Lancet Diabetes Endocrinol; 2016 Oct; 4(10):829-39. PubMed ID: 27477773
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins.
    Baigent C; Keech A; Kearney PM; Blackwell L; Buck G; Pollicino C; Kirby A; Sourjina T; Peto R; Collins R; Simes R;
    Lancet; 2005 Oct; 366(9493):1267-78. PubMed ID: 16214597
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ezetimibe for the prevention of cardiovascular disease and all-cause mortality events.
    Zhan S; Tang M; Liu F; Xia P; Shu M; Wu X
    Cochrane Database Syst Rev; 2018 Nov; 11(11):CD012502. PubMed ID: 30480766
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.
    Sabatine MS; Wiviott SD; Im K; Murphy SA; Giugliano RP
    JAMA Cardiol; 2018 Sep; 3(9):823-828. PubMed ID: 30073316
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interpretation of the evidence for the efficacy and safety of statin therapy.
    Collins R; Reith C; Emberson J; Armitage J; Baigent C; Blackwell L; Blumenthal R; Danesh J; Smith GD; DeMets D; Evans S; Law M; MacMahon S; Martin S; Neal B; Poulter N; Preiss D; Ridker P; Roberts I; Rodgers A; Sandercock P; Schulz K; Sever P; Simes J; Smeeth L; Wald N; Yusuf S; Peto R
    Lancet; 2016 Nov; 388(10059):2532-2561. PubMed ID: 27616593
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.
    Silverman MG; Ference BA; Im K; Wiviott SD; Giugliano RP; Grundy SM; Braunwald E; Sabatine MS
    JAMA; 2016 Sep; 316(12):1289-97. PubMed ID: 27673306
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.
    Heart Protection Study Collaborative Group
    Lancet; 2002 Jul; 360(9326):7-22. PubMed ID: 12114036
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.
    ; Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C
    Lancet; 2008 Jan; 371(9607):117-25. PubMed ID: 18191683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.
    Ridker PM; Danielson E; Fonseca FA; Genest J; Gotto AM; Kastelein JJ; Koenig W; Libby P; Lorenzatti AJ; Macfadyen JG; Nordestgaard BG; Shepherd J; Willerson JT; Glynn RJ;
    Lancet; 2009 Apr; 373(9670):1175-82. PubMed ID: 19329177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
    Baigent C; Landray MJ; Reith C; Emberson J; Wheeler DC; Tomson C; Wanner C; Krane V; Cass A; Craig J; Neal B; Jiang L; Hooi LS; Levin A; Agodoa L; Gaziano M; Kasiske B; Walker R; Massy ZA; Feldt-Rasmussen B; Krairittichai U; Ophascharoensuk V; Fellström B; Holdaas H; Tesar V; Wiecek A; Grobbee D; de Zeeuw D; Grönhagen-Riska C; Dasgupta T; Lewis D; Herrington W; Mafham M; Majoni W; Wallendszus K; Grimm R; Pedersen T; Tobert J; Armitage J; Baxter A; Bray C; Chen Y; Chen Z; Hill M; Knott C; Parish S; Simpson D; Sleight P; Young A; Collins R;
    Lancet; 2011 Jun; 377(9784):2181-92. PubMed ID: 21663949
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association Between Intensity of Low-Density Lipoprotein Cholesterol Reduction With Statin-Based Therapies and Secondary Stroke Prevention: A Meta-analysis of Randomized Clinical Trials.
    Lee M; Cheng CY; Wu YL; Lee JD; Hsu CY; Ovbiagele B
    JAMA Neurol; 2022 Apr; 79(4):349-358. PubMed ID: 35188949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
    ;
    Lancet Diabetes Endocrinol; 2024 May; 12(5):306-319. PubMed ID: 38554713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intensive LDL cholesterol-lowering treatment beyond current recommendations for the prevention of major vascular events: a systematic review and meta-analysis of randomised trials including 327 037 participants.
    Wang N; Fulcher J; Abeysuriya N; Park L; Kumar S; Di Tanna GL; Wilcox I; Keech A; Rodgers A; Lal S
    Lancet Diabetes Endocrinol; 2020 Jan; 8(1):36-49. PubMed ID: 31862150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials.
    Gencer B; Marston NA; Im K; Cannon CP; Sever P; Keech A; Braunwald E; Giugliano RP; Sabatine MS
    Lancet; 2020 Nov; 396(10263):1637-1643. PubMed ID: 33186535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial.
    Heart Protection Study Collaborative Group
    Lancet; 2011 Dec; 378(9808):2013-2020. PubMed ID: 22115874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials.
    Marston NA; Giugliano RP; Im K; Silverman MG; O'Donoghue ML; Wiviott SD; Ference BA; Sabatine MS
    Circulation; 2019 Oct; 140(16):1308-1317. PubMed ID: 31530008
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 60.