399 related articles for article (PubMed ID: 25581064)
1. Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase.
Wang F; Wang Y; Ji J; Zhou Z; Yu J; Zhu H; Su Z; Zhang L; Zheng J
ACS Chem Biol; 2015 Apr; 10(4):1017-25. PubMed ID: 25581064
[TBL] [Abstract][Full Text] [Related]
2. Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
Kalkreuter E; Bingham KS; Keeler AM; Lowell AN; Schmidt JJ; Sherman DH; Williams GJ
Nat Commun; 2021 Apr; 12(1):2193. PubMed ID: 33850151
[TBL] [Abstract][Full Text] [Related]
3. Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase.
Zhang F; Shi T; Ji H; Ali I; Huang S; Deng Z; Min Q; Bai L; Zhao Y; Zheng J
Biochemistry; 2019 Jul; 58(27):2978-2986. PubMed ID: 31199122
[TBL] [Abstract][Full Text] [Related]
4. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Liou GF; Lau J; Cane DE; Khosla C
Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
[TBL] [Abstract][Full Text] [Related]
5. Commodity Chemicals From Engineered Modular Type I Polyketide Synthases.
Yuzawa S; Zargar A; Pang B; Katz L; Keasling JD
Methods Enzymol; 2018; 608():393-415. PubMed ID: 30173771
[TBL] [Abstract][Full Text] [Related]
6. Rational engineering acyltransferase domain of modular polyketide synthase for expanding substrate specificity.
Zhang W; Zhou L; Li C; Deng Z; Qu X
Methods Enzymol; 2019; 622():271-292. PubMed ID: 31155056
[TBL] [Abstract][Full Text] [Related]
7. Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS.
Musiol EM; Härtner T; Kulik A; Moldenhauer J; Piel J; Wohlleben W; Weber T
Chem Biol; 2011 Apr; 18(4):438-44. PubMed ID: 21513880
[TBL] [Abstract][Full Text] [Related]
8. Function analysis of a new type I PKS-SAT domain by SAT-EAT domain replacement.
Jiao YL; Wang LH; Jiao BH; Wang SJ; Fang YW; Liu S
Prikl Biokhim Mikrobiol; 2010; 46(2):161-5. PubMed ID: 20391758
[TBL] [Abstract][Full Text] [Related]
9. Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production.
Yuzawa S; Deng K; Wang G; Baidoo EE; Northen TR; Adams PD; Katz L; Keasling JD
ACS Synth Biol; 2017 Jan; 6(1):139-147. PubMed ID: 27548700
[TBL] [Abstract][Full Text] [Related]
10. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.
Koryakina I; Kasey C; McArthur JB; Lowell AN; Chemler JA; Li S; Hansen DA; Sherman DH; Williams GJ
ACS Chem Biol; 2017 Jan; 12(1):114-123. PubMed ID: 28103677
[TBL] [Abstract][Full Text] [Related]
11. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
[TBL] [Abstract][Full Text] [Related]
12. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
Lau J; Fu H; Cane DE; Khosla C
Biochemistry; 1999 Feb; 38(5):1643-51. PubMed ID: 9931032
[TBL] [Abstract][Full Text] [Related]
13. Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
Zhang F; Ji H; Ali I; Deng Z; Bai L; Zheng J
Chembiochem; 2020 May; 21(9):1309-1314. PubMed ID: 31777147
[TBL] [Abstract][Full Text] [Related]
14. Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.
Siskos AP; Baerga-Ortiz A; Bali S; Stein V; Mamdani H; Spiteller D; Popovic B; Spencer JB; Staunton J; Weissman KJ; Leadlay PF
Chem Biol; 2005 Oct; 12(10):1145-53. PubMed ID: 16242657
[TBL] [Abstract][Full Text] [Related]
15. Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.
Li Y; Zhang W; Zhang H; Tian W; Wu L; Wang S; Zheng M; Zhang J; Sun C; Deng Z; Sun Y; Qu X; Zhou J
Angew Chem Int Ed Engl; 2018 May; 57(20):5823-5827. PubMed ID: 29536601
[TBL] [Abstract][Full Text] [Related]
16. Type I polyketide synthases that require discrete acyltransferases.
Cheng YQ; Coughlin JM; Lim SK; Shen B
Methods Enzymol; 2009; 459():165-86. PubMed ID: 19362640
[TBL] [Abstract][Full Text] [Related]
17. Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry.
Annaval T; Paris C; Leadlay PF; Jacob C; Weissman KJ
Chembiochem; 2015 Jun; 16(9):1357-64. PubMed ID: 25851784
[TBL] [Abstract][Full Text] [Related]
18. Mutagenesis of a modular polyketide synthase enoylreductase domain reveals insights into catalysis and stereospecificity.
Kwan DH; Leadlay PF
ACS Chem Biol; 2010 Sep; 5(9):829-38. PubMed ID: 20666435
[TBL] [Abstract][Full Text] [Related]
19. Functional and Structural Analyses of the Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin.
Kawasaki D; Miyanaga A; Chisuga T; Kudo F; Eguchi T
Biochemistry; 2019 Dec; 58(48):4799-4803. PubMed ID: 31721563
[TBL] [Abstract][Full Text] [Related]
20. Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases.
Yadav G; Gokhale RS; Mohanty D
J Mol Biol; 2003 Apr; 328(2):335-63. PubMed ID: 12691745
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
