BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 25581168)

  • 1. The elastase-PK101 structure: mechanism of an ultrasensitive activity-based probe revealed.
    Lechtenberg BC; Kasperkiewicz P; Robinson H; Drag M; Riedl SJ
    ACS Chem Biol; 2015 Apr; 10(4):945-51. PubMed ID: 25581168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase.
    Leahy D; Grant C; Jackson A; Duff A; Tardiota N; Van Haeften J; Chen X; Peake JM; Kruppa MD; Smith ET; Johnson DA; Lott WB; Harris JM
    Molecules; 2021 Sep; 26(17):. PubMed ID: 34500777
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct interaction of ONO-5046 with human neutrophil elastase through ¹H NMR and molecular docking.
    Feng L; Zhu W; Huang C; Li Y
    Int J Biol Macromol; 2012 Oct; 51(3):196-200. PubMed ID: 22579959
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polar Desolvation and Position 226 of Pancreatic and Neutrophil Elastases Are Crucial to their Affinity for the Kunitz-Type Inhibitors ShPI-1 and ShPI-1/K13L.
    Hernández González JE; García-Fernández R; Valiente PA
    PLoS One; 2015; 10(9):e0137787. PubMed ID: 26372354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Complex of human neutrophil elastase with 1/2SLPI.
    Koizumi M; Fujino A; Fukushima K; Kamimura T; Takimoto-Kamimura M
    J Synchrotron Radiat; 2008 May; 15(Pt 3):308-11. PubMed ID: 18421166
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
    Hansen G; Gielen-Haertwig H; Reinemer P; Schomburg D; Harrenga A; Niefind K
    J Mol Biol; 2011 Jun; 409(5):681-91. PubMed ID: 21549129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and use of highly specific substrates of neutrophil elastase and proteinase 3.
    Korkmaz B; Attucci S; Moreau T; Godat E; Juliano L; Gauthier F
    Am J Respir Cell Mol Biol; 2004 Jun; 30(6):801-7. PubMed ID: 14693667
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site.
    Jobichen C; Prabhakar MT; Loh SN; Sivaraman J
    Biochemistry; 2020 Aug; 59(30):2788-2795. PubMed ID: 32657577
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling.
    Kasperkiewicz P; Poreba M; Snipas SJ; Parker H; Winterbourn CC; Salvesen GS; Drag M
    Proc Natl Acad Sci U S A; 2014 Feb; 111(7):2518-23. PubMed ID: 24550277
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Staphylococcus aureus evasion proteins EapH1 and EapH2: Residue-level investigation of an alternative binding motif for human neutrophil elastase.
    Herdendorf TJ; Geisbrecht BV
    Arch Biochem Biophys; 2019 Nov; 676():108140. PubMed ID: 31622584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the P2 residue of human alpha 1-antitrypsin in determining target protease specificity.
    Chung HS; Kim JS; Lee SM; Park SJ
    PLoS One; 2017; 12(9):e0185074. PubMed ID: 28922398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bioinformatic analysis of protein structure-function relationships: case study of leukocyte elastase (ELA2) missense mutations.
    Thusberg J; Vihinen M
    Hum Mutat; 2006 Dec; 27(12):1230-43. PubMed ID: 16986121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
    Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel mechanism to enhance tPA-induced fibrinolysis: effect of limited proteolysis of PAI-1 by neutrophil elastase.
    Urano T; Wu K; Ihara H; Takada Y; Takada A
    Pol J Pharmacol; 1996; 48(2):209-13. PubMed ID: 9112653
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human neutrophil elastase: mediator and therapeutic target in atherosclerosis.
    Henriksen PA; Sallenave JM
    Int J Biochem Cell Biol; 2008; 40(6-7):1095-100. PubMed ID: 18289916
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151).
    Macdonald SJ; Dowle MD; Harrison LA; Clarke GD; Inglis GG; Johnson MR; Shah P; Smith RA; Amour A; Fleetwood G; Humphreys DC; Molloy CR; Dixon M; Godward RE; Wonacott AJ; Singh OM; Hodgson ST; Hardy GW
    J Med Chem; 2002 Aug; 45(18):3878-90. PubMed ID: 12190311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the P6-P3' region of the serpin reactive loop in the formation and breakdown of the inhibitory complex.
    Plotnick MI; Schechter NM; Wang ZM; Liu X; Rubin H
    Biochemistry; 1997 Nov; 36(47):14601-8. PubMed ID: 9398179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inspection of the binding sites of proteinase3 for the design of a highly specific substrate.
    Hajjar E; Korkmaz B; Gauthier F; Brandsdal BO; Witko-Sarsat V; Reuter N
    J Med Chem; 2006 Feb; 49(4):1248-60. PubMed ID: 16480262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.
    Nunes GL; Simões A; Dyszy FH; Shida CS; Juliano MA; Juliano L; Gesteira TF; Nader HB; Murphy G; Chaffotte AF; Goldberg ME; Tersariol IL; Almeida PC
    PLoS One; 2011; 6(6):e21525. PubMed ID: 21731773
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New insights into the inhibition of human neutrophil elastase by heparin.
    Spencer JL; Stone PJ; Nugent MA
    Biochemistry; 2006 Aug; 45(30):9104-20. PubMed ID: 16866356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.