BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 25581261)

  • 1. Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread.
    Shen Y; Zificsak CA; Shea JE; Lao X; Bollt O; Li X; Lisko JG; Theroff JP; Scaife CL; Ator MA; Ruggeri BA; Dorsey BD; Kuwada SK
    J Med Chem; 2015 Feb; 58(3):1140-58. PubMed ID: 25581261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of sulfonyl acrylonitriles as novel inhibitors to peritoneal carcinomatosis.
    Zificsak CA; Shen Y; Lisko JG; Theroff JP; Lao X; Bollt O; Li X; Dorsey BD; Kuwada SK
    Bioorg Med Chem Lett; 2012 Mar; 22(5):1850-3. PubMed ID: 22326395
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of (Z)-2,3-diphenylacrylonitrile analogs as anti-cancer and anti-microbial agents.
    Alam MS; Nam YJ; Lee DU
    Eur J Med Chem; 2013 Nov; 69():790-7. PubMed ID: 24113364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and bioactivity evaluation of 2,3-diaryl acrylonitrile derivatives as potential anticancer agents.
    Ma J; Li J; Tian YS
    Bioorg Med Chem Lett; 2017 Jan; 27(1):81-85. PubMed ID: 27887843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.
    Saczewski F; Reszka P; Gdaniec M; Grünert R; Bednarski PJ
    J Med Chem; 2004 Jun; 47(13):3438-49. PubMed ID: 15189040
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1.
    Bachovchin DA; Zuhl AM; Speers AE; Wolfe MR; Weerapana E; Brown SJ; Rosen H; Cravatt BF
    J Med Chem; 2011 Jul; 54(14):5229-36. PubMed ID: 21639134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of novel E-2-(2-thienyl)- and Z-2-(3-thienyl)-3-arylacrylonitriles as antifungal and anticancer agents.
    Quiroga J; Cobo D; Insuasty B; Abonía R; Nogueras M; Cobo J; Vásquez Y; Gupta M; Derita M; Zacchino S
    Arch Pharm (Weinheim); 2007 Nov; 340(11):603-6. PubMed ID: 17924362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of heteroaryl styryl sulfone derivatives as anticancer agents.
    Long Y; Yu M; Li P; Islam S; Goh AW; Kumarasiri M; Wang S
    Bioorg Med Chem Lett; 2016 Dec; 26(23):5674-5678. PubMed ID: 27815119
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and pharmacological evaluation of 2,3-diphenyl acrylonitriles-bearing halogen as selective anticancer agents.
    Li JJ; Ma J; Xin YB; Quan ZS; Tian YS
    Chem Biol Drug Des; 2018 Aug; 92(2):1419-1428. PubMed ID: 29516624
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.
    Saczewski F; Stencel A; Bieńczak AM; Langowska KA; Michaelis M; Werel W; Hałasa R; Reszka P; Bednarski PJ
    Eur J Med Chem; 2008 Sep; 43(9):1847-57. PubMed ID: 18187237
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line.
    Gnanasekaran KK; Benbrook DM; Nammalwar B; Thavathiru E; Bunce RA; Berlin KD
    Eur J Med Chem; 2015; 96():209-17. PubMed ID: 25880346
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of (E)-styrylbenzylsulfones as novel anticancer agents.
    Reddy MV; Mallireddigari MR; Cosenza SC; Pallela VR; Iqbal NM; Robell KA; Kang AD; Reddy EP
    J Med Chem; 2008 Jan; 51(1):86-100. PubMed ID: 18088089
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities.
    Lu T; Goh AW; Yu M; Adams J; Lam F; Teo T; Li P; Noll B; Zhong L; Diab S; Chahrour O; Hu A; Abbas AY; Liu X; Huang S; Sumby CJ; Milne R; Midgley C; Wang S
    J Med Chem; 2014 Mar; 57(6):2275-91. PubMed ID: 24471873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells.
    Bourguet CB; Boulay PL; Claing A; Lubell WD
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3361-5. PubMed ID: 24986663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel acrylonitrile derived imidazo[4,5-b]pyridines as antioxidants and potent antiproliferative agents for pancreatic adenocarcinoma.
    Boček Pavlinac I; Persoons L; Daelemans D; Starčević K; Vianello R; Hranjec M
    Int J Biol Macromol; 2024 May; 266(Pt 2):131239. PubMed ID: 38569992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, biological evaluation and molecular modeling studies of 1-aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)-hexen-1,5-diynes as a new class of potent antitumor agents.
    Lo YH; Lin YT; Liu YP; Duh TH; Lu PJ; Wu MJ
    Eur J Med Chem; 2013 Apr; 62():526-33. PubMed ID: 23419737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationship study of arylsulfonylimidazolidinones as anticancer agents.
    Sharma VK; Lee KC; Venkateswararao E; Joo C; Kim MS; Sharma N; Jung SH
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6829-32. PubMed ID: 21983438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel combretastatin analogues effective against murine solid tumors: design and structure-activity relationships.
    Ohsumi K; Nakagawa R; Fukuda Y; Hatanaka T; Morinaga Y; Nihei Y; Ohishi K; Suga Y; Akiyama Y; Tsuji T
    J Med Chem; 1998 Jul; 41(16):3022-32. PubMed ID: 9685242
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
    Harmange JC; Weiss MM; Germain J; Polverino AJ; Borg G; Bready J; Chen D; Choquette D; Coxon A; DeMelfi T; DiPietro L; Doerr N; Estrada J; Flynn J; Graceffa RF; Harriman SP; Kaufman S; La DS; Long A; Martin MW; Neervannan S; Patel VF; Potashman M; Regal K; Roveto PM; Schrag ML; Starnes C; Tasker A; Teffera Y; Wang L; White RD; Whittington DA; Zanon R
    J Med Chem; 2008 Mar; 51(6):1649-67. PubMed ID: 18324761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of some novel substituted quinazolines as antitumor agents.
    Alanazi AM; Abdel-Aziz AA; Al-Suwaidan IA; Abdel-Hamide SG; Shawer TZ; El-Azab AS
    Eur J Med Chem; 2014 May; 79():446-54. PubMed ID: 24763265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.