BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 25582615)

  • 1. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids.
    Thareja S; Rajpoot T; Verma SK
    Steroids; 2015 Mar; 95():96-103. PubMed ID: 25582615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Steroidal 5α-Reductase Inhibitors: A Comparative 3D-QSAR Study Review.
    Thareja S
    Chem Rev; 2015 Apr; 115(8):2883-94. PubMed ID: 25785489
    [No Abstract]   [Full Text] [Related]  

  • 3. A review on steroidal 5α-reductase inhibitors for treatment of benign prostatic hyperplasia.
    Sun J; Xiang H; Yang LL; Chen JB
    Curr Med Chem; 2011; 18(23):3576-89. PubMed ID: 21756226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: a self organizing molecular field analysis approach.
    Aggarwal S; Thareja S; Bhardwaj TR; Kumar M
    Eur J Med Chem; 2010 Feb; 45(2):476-81. PubMed ID: 19906465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determination of rat 5alpha-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines.
    Szécsi M; Ondré D; Tóth I; Magony S; Wölfling J; Schneider G; Julesz J
    Acta Biol Hung; 2010 Sep; 61(3):274-81. PubMed ID: 20724274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5alpha-reductase inhibitors.
    Bratoeff E; Cabeza M; Pérez-Ornelas V; Recillas S; Heuze I
    J Steroid Biochem Mol Biol; 2008 Sep; 111(3-5):275-81. PubMed ID: 18644453
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.
    Issa S; Schnabel D; Feix M; Wolf L; Schaefer HE; Russell DW; Schweikert HU
    J Clin Endocrinol Metab; 2002 Dec; 87(12):5401-7. PubMed ID: 12466325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. QSARs for 6-azasteroids as inhibitors of human type 1 5alpha-reductase: prediction of binding affinity and selectivity relative to 3-BHSD.
    Bakken GA; Jurs PC
    J Chem Inf Comput Sci; 2001; 41(5):1255-65. PubMed ID: 11604025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism based representation of the active site of 5 alpha-reductase (5AR).
    Ahmed S; Denison S
    Bioorg Med Chem Lett; 1998 Sep; 8(18):2615-70. PubMed ID: 9873591
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Self organizing molecular field analysis on a series of human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroid.
    Thareja S; Aggarwal S; Bhardwaj TR; Kumar M
    Eur J Med Chem; 2009 Dec; 44(12):4920-5. PubMed ID: 19716209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Re: 5α-Reductase Type 1 Modulates Insulin Sensitivity in Men.
    Kaplan SA
    J Urol; 2015 Sep; 194(3):736-7. PubMed ID: 26292878
    [No Abstract]   [Full Text] [Related]  

  • 12. Novel and Predictive QSAR Model for Steroidal and Nonsteroidal 5α- Reductase Type II Inhibitors.
    Mando H; Hassan A; Gharaghani S
    Curr Drug Discov Technol; 2021; 18(2):317-332. PubMed ID: 32208118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Self-organizing molecular field analysis on pregnane derivatives as human steroidal 5alpha-reductase inhibitors.
    Aggarwal S; Thareja S; Bhardwaj TR; Kumar M
    Steroids; 2010 Jun; 75(6):411-8. PubMed ID: 20170668
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Linear relationships between the ligand binding energy and the activation energy of time-dependent inhibition of steroid 5alpha-reductase by delta 1-4-azasteroids.
    Tian G; Haffner CD
    J Biol Chem; 2001 Jun; 276(24):21359-64. PubMed ID: 11279132
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dutasteride affects progesterone metabolizing enzyme activity/expression in human breast cell lines resulting in suppression of cell proliferation and detachment.
    Wiebe JP; Souter L; Zhang G
    J Steroid Biochem Mol Biol; 2006 Aug; 100(4-5):129-40. PubMed ID: 16806904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists.
    Lao K; Sun J; Wang C; Wang Y; You Q; Xiao H; Xiang H
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4212-4217. PubMed ID: 28757062
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploration of Novel 5α-Reductase Inhibitors for Benign Prostatic Hyperplasia by 2D/3D QSAR, Cytotoxicity Pre-ADME and Docking Studies.
    Dhingra R; Malhotra M; Sharma V; Bhardwaj TR; Dhingra N
    Curr Top Med Chem; 2018; 18(32):2816-2834. PubMed ID: 30659542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors.
    Karnsomwan W; Netcharoensirisuk P; Rungrotmongkol T; De-Eknamkul W; Chamni S
    Chem Pharm Bull (Tokyo); 2017; 65(3):253-260. PubMed ID: 28250347
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the 5alpha-reductase-3alpha-hydroxysteroid dehydrogenase complex in the human brain.
    Steckelbroeck S; Watzka M; Reichelt R; Hans VH; Stoffel-Wagner B; Heidrich DD; Schramm J; Bidlingmaier F; Klingmüller D
    J Clin Endocrinol Metab; 2001 Mar; 86(3):1324-31. PubMed ID: 11238528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The enzyme and inhibitors of 4-ene-3-oxosteroid 5 alpha-oxidoreductase.
    Li X; Chen C; Singh SM; Labrie F; Labire F [corrected to Labrie F]
    Steroids; 1995 Jun; 60(6):430-41. PubMed ID: 7676475
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.