BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 25584882)

  • 1. Bioanalysis of 6-diazo-5-oxo-l-norleucine in plasma and brain by ultra-performance liquid chromatography mass spectrometry.
    Alt J; Potter MC; Rojas C; Slusher BS
    Anal Biochem; 2015 Apr; 474():28-34. PubMed ID: 25584882
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Influence of 6-diazo-5-oxo-L-norleucine (DON), a glutamine analogue, on cartilaginous differentiation in mouse limb buds in vitro.
    Aydelotte MB; Kochhar DM
    Differentiation; 1975 Oct; 4(2):73-80. PubMed ID: 1183764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. L-asparaginase and 6-diazo-5-oxo-L-norleucine synergistically inhibit the growth of glioblastoma cells.
    Ohba S; Hirose Y
    J Neurooncol; 2020 Feb; 146(3):469-475. PubMed ID: 32020477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine.
    Wang SZ; Poore B; Alt J; Price A; Allen SJ; Hanaford AR; Kaur H; Orr BA; Slusher BS; Eberhart CG; Raabe EH; Rubens JA
    Clin Cancer Res; 2019 Oct; 25(19):5925-5936. PubMed ID: 31300448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Limb development in mouse embryos: protection against teratogenic effects of 6-diazo-5-ox-L-norleucine (DON) in vivo and in vitro.
    Greene RM; Kochhar DM
    J Embryol Exp Morphol; 1975 Apr; 33(2):355-70. PubMed ID: 1176851
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast.
    Willis RC; Seegmiller JE
    J Cell Physiol; 1977 Dec; 93(3):375-82. PubMed ID: 22551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.
    Manivannan S; Baxter VK; Schultz KL; Slusher BS; Griffin DE
    J Virol; 2016 Oct; 90(20):9251-62. PubMed ID: 27489275
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 6-DIAZO-5-OXO-L-NORLEUCINE INHIBITION OF ESCHERICHIA COLI.
    COGGIN JH; MARTIN WR
    J Bacteriol; 1965 May; 89(5):1348-53. PubMed ID: 14293024
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
    Rais R; Jančařík A; Tenora L; Nedelcovych M; Alt J; Englert J; Rojas C; Le A; Elgogary A; Tan J; Monincová L; Pate K; Adams R; Ferraris D; Powell J; Majer P; Slusher BS
    J Med Chem; 2016 Sep; 59(18):8621-33. PubMed ID: 27560860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficacy of 6-diazo-5-oxo-L-norleucine and N-[N-gamma-glutamyl-6-diazo-5-oxo-norleucinyl]-6-diazo-5-oxo-norleucine against experimental tumors in conventional and nude mice.
    Ovejera AA; Houchens DP; Catane R; Sheridan MA; Muggia FM
    Cancer Res; 1979 Aug; 39(8):3220-4. PubMed ID: 572261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders.
    Nedelcovych MT; Tenora L; Kim BH; Kelschenbach J; Chao W; Hadas E; Jančařík A; Prchalová E; Zimmermann SC; Dash RP; Gadiano AJ; Garrett C; Furtmüller G; Oh B; Brandacher G; Alt J; Majer P; Volsky DJ; Rais R; Slusher BS
    J Med Chem; 2017 Aug; 60(16):7186-7198. PubMed ID: 28759224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determination of 6-diazo-5-oxo-L-norleucine in plasma and urine by reversed-phase high-performance liquid chromatography of the dansyl derivative.
    Powis G; Ames MM
    J Chromatogr; 1980 Jan; 181(1):95-9. PubMed ID: 7364921
    [No Abstract]   [Full Text] [Related]  

  • 13. Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
    Ortlund E; Lacount MW; Lewinski K; Lebioda L
    Biochemistry; 2000 Feb; 39(6):1199-204. PubMed ID: 10684596
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis.
    Pham K; Maxwell MJ; Sweeney H; Alt J; Rais R; Eberhart CG; Slusher BS; Raabe EH
    J Neuropathol Exp Neurol; 2021 Mar; 80(4):336-344. PubMed ID: 33712838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor.
    Gao RD; Hin N; Prchalová E; Pal A; Lam J; Rais R; Slusher BS; Tsukamoto T
    Bioorg Med Chem Lett; 2021 Oct; 50():128321. PubMed ID: 34400301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transport and membrane binding of the glutamine analogue 6-diazo-5-oxo-L-norleucine (DON) in Xenopus laevis oocytes.
    Taylor PM; Mackenzie B; Hundal HS; Robertson E; Rennie MJ
    J Membr Biol; 1992 Jun; 128(3):181-91. PubMed ID: 1501246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The rediscovery of DON (6-diazo-5-oxo-L-norleucine).
    Kisner DL; Catane R; Muggia FM
    Recent Results Cancer Res; 1980; 74():258-63. PubMed ID: 7192426
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines.
    Huber KR; Rosenfeld H; Roberts J
    Int J Cancer; 1988 May; 41(5):752-5. PubMed ID: 3366493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of 6-diazo-5-oxo-L-norleucine (DON) on human carcinoid tumor cell aggregates.
    Wu F; Bergström M; Stridsberg M; Orlefors H; Eriksson B; Oberg K; Watanabe Y; Långstrom B
    Anticancer Res; 1997; 17(4A):2363-7. PubMed ID: 9252648
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of
    Novotná K; Tenora L; Prchalová E; Paule J; Alt J; Veeravalli V; Lam J; Wu Y; Šnajdr I; Gori S; Mettu VS; Tsukamoto T; Majer P; Slusher BS; Rais R
    J Med Chem; 2023 Nov; 66(22):15493-15510. PubMed ID: 37949450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.