85 related articles for article (PubMed ID: 2558540)
21. Phase I and pharmacokinetic study of brequinar sodium (NSC 368390).
Noe DA; Rowinsky EK; Shen HS; Clarke BV; Grochow LB; McGuire WB; Hantel A; Adams DB; Abeloff MD; Ettinger DS
Cancer Res; 1990 Aug; 50(15):4595-9. PubMed ID: 2369734
[TBL] [Abstract][Full Text] [Related]
22. Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
He T; Haapa-Paananen S; Kaminskyy VO; Kohonen P; Fey V; Zhivotovsky B; Kallioniemi O; Perälä M
Oncogene; 2014 Jul; 33(27):3538-49. PubMed ID: 24013224
[TBL] [Abstract][Full Text] [Related]
23. Brequinar potentiates 5-fluorouracil antitumor activity in a murine model colon 38 tumor by tissue-specific modulation of uridine nucleotide pools.
Pizzorno G; Wiegand RA; Lentz SK; Handschumacher RE
Cancer Res; 1992 Apr; 52(7):1660-5. PubMed ID: 1551097
[TBL] [Abstract][Full Text] [Related]
24. Phase I clinical and pharmacokinetic trial of Brequinar sodium (DuP 785; NSC 368390).
Arteaga CL; Brown TD; Kuhn JG; Shen HS; O'Rourke TJ; Beougher K; Brentzel HJ; Von Hoff DD; Weiss GR
Cancer Res; 1989 Aug; 49(16):4648-53. PubMed ID: 2743343
[TBL] [Abstract][Full Text] [Related]
25. Leishmania mexicana: conversion of dihydroorotate to orotate in amastigotes and promastigotes.
Gero AM; Coombs GH
Exp Parasitol; 1982 Oct; 54(2):185-95. PubMed ID: 6290253
[No Abstract] [Full Text] [Related]
26. Effects of chaotropic agents versus detergents on dihydroorotate dehydrogenase.
Forman HJ; Kennedy J
J Biol Chem; 1977 May; 252(10):3379-81. PubMed ID: 193834
[TBL] [Abstract][Full Text] [Related]
27. Distribution of the novel anticancer drug candidate Brequinar sodium (DuP 785, NSC 368390) into normal and tumor tissues of nude mice bearing human colon carcinoma xenografts.
Shen HS; Chen SF; Behrens DL; Whitney CC; Dexter DL; Forbes M
Cancer Chemother Pharmacol; 1988; 22(3):183-6. PubMed ID: 3409452
[TBL] [Abstract][Full Text] [Related]
28. On the role of dihydroorotate dehydrogenase in growth cessation of Ehrlich ascites tumor cells cultured under oxygen deficiency.
Löffler M
Eur J Biochem; 1980; 107(1):207-15. PubMed ID: 6249586
[TBL] [Abstract][Full Text] [Related]
29. Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the compare program.
Cleaveland ES; Monks A; Vaigro-Wolff A; Zaharevitz DW; Paull K; Ardalan K; Cooney DA; Ford H
Biochem Pharmacol; 1995 Mar; 49(7):947-54. PubMed ID: 7741767
[TBL] [Abstract][Full Text] [Related]
30. Comparative studies on dihydroorotate dehydrogenase from P. berghei and the mouse reticulocyte.
Gero AM; Finney KG; Bennett JC; O'Sullivan WJ
Aust J Exp Biol Med Sci; 1981 Aug; 59(4):477-90. PubMed ID: 6271112
[TBL] [Abstract][Full Text] [Related]
31. Human spleen dihydroorotate dehydrogenase: properties and partial purification.
Gero AM; O'Sullivan WJ
Biochem Med; 1985 Aug; 34(1):70-82. PubMed ID: 2996511
[TBL] [Abstract][Full Text] [Related]
32. Dihydroorotate dehydrogenase, orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in Plasmodium falciparum.
Gero AM; Tetley K; Coombs GH; Phillips RS
Trans R Soc Trop Med Hyg; 1981; 75(5):719-20. PubMed ID: 6277049
[No Abstract] [Full Text] [Related]
33. Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase.
Hurt DE; Sutton AE; Clardy J
Bioorg Med Chem Lett; 2006 Mar; 16(6):1610-5. PubMed ID: 16406782
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of synthesis of pyrimidine nucleotides by 2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone.
Bennett LL; Smithers D; Rose LM; Adamson DJ; Thomas HJ
Cancer Res; 1979 Dec; 39(12):4868-74. PubMed ID: 227592
[No Abstract] [Full Text] [Related]
35. Analysis of the kinetic mechanism of the bovine liver mitochondrial dihydroorotate dehydrogenase.
Hines V; Johnston M
Biochemistry; 1989 Feb; 28(3):1222-6. PubMed ID: 2540819
[TBL] [Abstract][Full Text] [Related]
36. The anaerobic oxidation of dihydroorotate by Escherichia coli K-12.
Andrews S; Cox GB; Gibson F
Biochim Biophys Acta; 1977 Oct; 462(1):153-60. PubMed ID: 199252
[TBL] [Abstract][Full Text] [Related]
37. Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation of UMP biosynthesis.
Jones ME
Annu Rev Biochem; 1980; 49():253-79. PubMed ID: 6105839
[No Abstract] [Full Text] [Related]
38. Pharmacokinetics of Brequinar sodium (NSC 368390; DUP 785) in cerebrospinal fluid.
Schwartsmann G; van der Vijgh WJ; Klein I; van Groeningen CJ; Vermorken JB; Pinedo HM
Eur J Cancer Clin Oncol; 1988 Dec; 24(12):1903-4. PubMed ID: 3220087
[No Abstract] [Full Text] [Related]
39. Anti-arthritic effects of KF20444, a new immunosuppressive compound inhibiting dihydroorotate dehydrogenase, on rat collagen-induced arthritis.
Kobayashi K; Nakashima A; Nagata H; Nakajima H; Yamaguchi K; Sato S; Miki I
Inflamm Res; 2001 Jan; 50(1):24-31. PubMed ID: 11235018
[TBL] [Abstract][Full Text] [Related]
40. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase.
Boa AN; Canavan SP; Hirst PR; Ramsey C; Stead AM; McConkey GA
Bioorg Med Chem; 2005 Mar; 13(6):1945-67. PubMed ID: 15727850
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
