140 related articles for article (PubMed ID: 25588041)
21. p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells.
Sandhu C; Peehl DM; Slingerland J
Cancer Res; 2000 May; 60(10):2616-22. PubMed ID: 10825132
[TBL] [Abstract][Full Text] [Related]
22. Growth factors and melanomas.
Halaban R
Semin Oncol; 1996 Dec; 23(6):673-81. PubMed ID: 8970586
[TBL] [Abstract][Full Text] [Related]
23. The role of cell cycle regulatory proteins in the pathogenesis of melanoma.
Li W; Sanki A; Karim RZ; Thompson JF; Soon Lee C; Zhuang L; McCarthy SW; Scolyer RA
Pathology; 2006 Aug; 38(4):287-301. PubMed ID: 16916716
[TBL] [Abstract][Full Text] [Related]
24. Mutational analysis of selected genes in the TGFbeta, Wnt, pRb, and p53 pathways in primary uveal melanoma.
Edmunds SC; Kelsell DP; Hungerford JL; Cree IA
Invest Ophthalmol Vis Sci; 2002 Sep; 43(9):2845-51. PubMed ID: 12202501
[TBL] [Abstract][Full Text] [Related]
25. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
Coppock DL; Buffolino P; Kopman C; Nathanson L
Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
[TBL] [Abstract][Full Text] [Related]
26. p16 proteins from melanoma-prone families are deficient in binding to Cdk4.
Reymond A; Brent R
Oncogene; 1995 Sep; 11(6):1173-8. PubMed ID: 7566978
[TBL] [Abstract][Full Text] [Related]
27. CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation.
Della Torre G; Pasini B; Frigerio S; Donghi R; Rovini D; Delia D; Peters G; Huot TJ; Bianchi-Scarra G; Lantieri F; Rodolfo M; Parmiani G; Pierotti MA
Br J Cancer; 2001 Sep; 85(6):836-44. PubMed ID: 11556834
[TBL] [Abstract][Full Text] [Related]
28. A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors.
Eliades P; Miller DM; Miao B; Kumar R; Taylor M; Buch S; Srinivasa SP; Flaherty KT; Tsao H
Cancer Biol Ther; 2016 Jul; 17(7):778-84. PubMed ID: 26810603
[TBL] [Abstract][Full Text] [Related]
29. Activin A induction of cell-cycle arrest involves modulation of cyclin D2 and p21CIP1/WAF1 in plasmacytic cells.
Yamato K; Koseki T; Ohguchi M; Kizaki M; Ikeda Y; Nishihara T
Mol Endocrinol; 1997 Jul; 11(8):1044-52. PubMed ID: 9212052
[TBL] [Abstract][Full Text] [Related]
30. E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation.
Jiao W; Lin HM; Timmons J; Nagaich AK; Ng SW; Misteli T; Rane SG
Cancer Res; 2005 May; 65(10):4067-77. PubMed ID: 15899796
[TBL] [Abstract][Full Text] [Related]
31. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
[TBL] [Abstract][Full Text] [Related]
32. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras.
Tremain R; Marko M; Kinnimulki V; Ueno H; Bottinger E; Glick A
Oncogene; 2000 Mar; 19(13):1698-709. PubMed ID: 10763827
[TBL] [Abstract][Full Text] [Related]
33. Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activity.
Li J; Li H; Tsai MD
Biochemistry; 2003 Jun; 42(22):6921-8. PubMed ID: 12779347
[TBL] [Abstract][Full Text] [Related]
34. Structural analysis of the inhibition of Cdk4 and Cdk6 by p16(INK4a) through molecular dynamics simulations.
Villacañas O; Pérez JJ; Rubio-Martínez J
J Biomol Struct Dyn; 2002 Dec; 20(3):347-58. PubMed ID: 12437373
[TBL] [Abstract][Full Text] [Related]
35. The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity.
Calbó J; Serna C; Garriga J; Graña X; Mazo A
Cell Death Differ; 2004 Oct; 11(10):1055-65. PubMed ID: 15309028
[TBL] [Abstract][Full Text] [Related]
36. P16Ink4a tumor suppressor function in lung cancer cells involves cyclin-dependent kinase 2 inhibition by Cip/Kip protein redistribution.
Grimison B; Langan TA; Sclafani RA
Cell Growth Differ; 2000 Oct; 11(10):507-15. PubMed ID: 11063124
[TBL] [Abstract][Full Text] [Related]
37. [Cyclin-dependent kinase inhibitory proteins in normal and transformed choroidal melanocytes].
Mouriaux F; Maurage CA; Labalette P; Casagrande F; Malecaze F; Darbon JM
J Fr Ophtalmol; 1999 Apr; 22(3):339-46. PubMed ID: 10337591
[TBL] [Abstract][Full Text] [Related]
38. The physiology of p16(INK4A)-mediated G1 proliferative arrest.
Shapiro GI; Edwards CD; Rollins BJ
Cell Biochem Biophys; 2000; 33(2):189-97. PubMed ID: 11325039
[TBL] [Abstract][Full Text] [Related]
39. The p16(INK4A) protein and flavopiridol restore yeast cell growth inhibited by Cdk4.
Moorthamer M; Panchal M; Greenhalf W; Chaudhuri B
Biochem Biophys Res Commun; 1998 Sep; 250(3):791-7. PubMed ID: 9784425
[TBL] [Abstract][Full Text] [Related]
40. Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Kovar H; Jug G; Aryee DN; Zoubek A; Ambros P; Gruber B; Windhager R; Gadner H
Oncogene; 1997 Oct; 15(18):2225-32. PubMed ID: 9393981
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]