These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
589 related articles for article (PubMed ID: 25590803)
81. The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism. Zaanan A; Okamoto K; Kawakami H; Khazaie K; Huang S; Sinicrope FA J Biol Chem; 2015 Sep; 290(39):23838-49. PubMed ID: 26245900 [TBL] [Abstract][Full Text] [Related]
82. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Tahir SK; Yang X; Anderson MG; Morgan-Lappe SE; Sarthy AV; Chen J; Warner RB; Ng SC; Fesik SW; Elmore SW; Rosenberg SH; Tse C Cancer Res; 2007 Feb; 67(3):1176-83. PubMed ID: 17283153 [TBL] [Abstract][Full Text] [Related]
83. Bcl-XL and Mcl-1 upregulation by calreticulin promotes apoptosis resistance of fibroblast-like synoviocytes via activation of PI3K/Akt and STAT3 pathways in rheumatoid arthritis. Jiao Y; Ding H; Huang S; Liu Y; Sun X; Wei W; Ma J; Zheng F Clin Exp Rheumatol; 2018; 36(5):841-849. PubMed ID: 29652658 [TBL] [Abstract][Full Text] [Related]
84. Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199). Phillips DC; Xiao Y; Lam LT; Litvinovich E; Roberts-Rapp L; Souers AJ; Leverson JD Blood Cancer J; 2015 Nov; 5(11):e368. PubMed ID: 26565405 [TBL] [Abstract][Full Text] [Related]
85. Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies. Al-Zebeeby A; Vogler M; Milani M; Richards C; Alotibi A; Greaves G; Dyer MJS; Cohen GM; Varadarajan S Haematologica; 2019 May; 104(5):1016-1025. PubMed ID: 30467206 [TBL] [Abstract][Full Text] [Related]
86. ABT-737 induces apoptosis in mantle cell lymphoma cells with a Bcl-2high/Mcl-1low profile and synergizes with other antineoplastic agents. Touzeau C; Dousset C; Bodet L; Gomez-Bougie P; Bonnaud S; Moreau A; Moreau P; Pellat-Deceunynck C; Amiot M; Le Gouill S Clin Cancer Res; 2011 Sep; 17(18):5973-81. PubMed ID: 21821698 [TBL] [Abstract][Full Text] [Related]
87. Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia. Kampa-Schittenhelm KM; Heinrich MC; Akmut F; Rasp KH; Illing B; Döhner H; Döhner K; Schittenhelm MM Mol Cancer; 2013 May; 12():46. PubMed ID: 23705826 [TBL] [Abstract][Full Text] [Related]
88. ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. Premkumar DR; Jane EP; DiDomenico JD; Vukmer NA; Agostino NR; Pollack IF J Pharmacol Exp Ther; 2012 Jun; 341(3):859-72. PubMed ID: 22393246 [TBL] [Abstract][Full Text] [Related]
89. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib. Hikita H; Takehara T; Shimizu S; Kodama T; Shigekawa M; Iwase K; Hosui A; Miyagi T; Tatsumi T; Ishida H; Li W; Kanto T; Hiramatsu N; Hayashi N Hepatology; 2010 Oct; 52(4):1310-21. PubMed ID: 20799354 [TBL] [Abstract][Full Text] [Related]
90. The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies. Paoluzzi L; Gonen M; Bhagat G; Furman RR; Gardner JR; Scotto L; Gueorguiev VD; Heaney ML; Manova K; O'Connor OA Blood; 2008 Oct; 112(7):2906-16. PubMed ID: 18591385 [TBL] [Abstract][Full Text] [Related]
91. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells. Longo PG; Laurenti L; Gobessi S; Sica S; Leone G; Efremov DG Blood; 2008 Jan; 111(2):846-55. PubMed ID: 17928528 [TBL] [Abstract][Full Text] [Related]
92. Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Shi J; Zhou Y; Huang HC; Mitchison TJ Cancer Res; 2011 Jul; 71(13):4518-26. PubMed ID: 21546570 [TBL] [Abstract][Full Text] [Related]
93. Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia. Pan R; Ruvolo VR; Wei J; Konopleva M; Reed JC; Pellecchia M; Andreeff M; Ruvolo PP Blood; 2015 Jul; 126(3):363-72. PubMed ID: 26045609 [TBL] [Abstract][Full Text] [Related]
94. Differential Expression of Bcl-2 Family Proteins Determines the Sensitivity of Human Follicular Lymphoma Cells to Dexamethasone-mediated and Anti-BCR-mediated Apoptosis. Adem J; Ropponen A; Eeva J; Eray M; Nuutinen U; Pelkonen J J Immunother; 2016 Jan; 39(1):8-14. PubMed ID: 26641257 [TBL] [Abstract][Full Text] [Related]
95. Tipping the balance: toward rational combination therapies to overcome venetoclax resistance in mantle cell lymphoma. Thus YJ; Eldering E; Kater AP; Spaargaren M Leukemia; 2022 Sep; 36(9):2165-2176. PubMed ID: 35725771 [TBL] [Abstract][Full Text] [Related]
96. The BCL-2 selective inhibitor ABT-199 sensitizes soft tissue sarcomas to proteasome inhibition by a concerted mechanism requiring BAX and NOXA. Muenchow A; Weller S; Hinterleitner C; Malenke E; Bugl S; Wirths S; Müller MR; Schulze-Osthoff K; Aulitzky WE; Kopp HG; Essmann F Cell Death Dis; 2020 Aug; 11(8):701. PubMed ID: 32839432 [TBL] [Abstract][Full Text] [Related]
97. Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway. Yu XS; Du J; Fan YJ; Liu FJ; Cao LL; Liang N; Xu DG; Zhang JD Oncotarget; 2016 Nov; 7(47):76827-76839. PubMed ID: 27765907 [TBL] [Abstract][Full Text] [Related]
98. Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax). Leverson JD; Zhang H; Chen J; Tahir SK; Phillips DC; Xue J; Nimmer P; Jin S; Smith M; Xiao Y; Kovar P; Tanaka A; Bruncko M; Sheppard GS; Wang L; Gierke S; Kategaya L; Anderson DJ; Wong C; Eastham-Anderson J; Ludlam MJ; Sampath D; Fairbrother WJ; Wertz I; Rosenberg SH; Tse C; Elmore SW; Souers AJ Cell Death Dis; 2015 Jan; 6(1):e1590. PubMed ID: 25590800 [TBL] [Abstract][Full Text] [Related]
99. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver. Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435 [TBL] [Abstract][Full Text] [Related]
100. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms. Paraiso KH; Haarberg HE; Wood E; Rebecca VW; Chen YA; Xiang Y; Ribas A; Lo RS; Weber JS; Sondak VK; John JK; Sarnaik AA; Koomen JM; Smalley KS Clin Cancer Res; 2012 May; 18(9):2502-14. PubMed ID: 22351686 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]