These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 25592869)

  • 1. CIP-36, a novel topoisomerase II-targeting agent, induces the apoptosis of multidrug-resistant cancer cells in vitro.
    Cao B; Chen H; Gao Y; Niu C; Zhang Y; Li L
    Int J Mol Med; 2015 Mar; 35(3):771-6. PubMed ID: 25592869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CS1 is a novel topoisomerase IIα inhibitor with favorable drug resistance profiles.
    Shen Y; Chen W; Zhao B; Hao H; Li Z; Lu C; Shen Y
    Biochem Biophys Res Commun; 2014 Oct; 453(3):302-8. PubMed ID: 25242524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of novel podophyllotoxin derivatives as potential antitumor agents.
    Cheng WH; Cao B; Shang H; Niu C; Zhang LM; Zhang ZH; Tian DL; Zhang S; Chen H; Zou ZM
    Eur J Med Chem; 2014 Oct; 85():498-507. PubMed ID: 25113878
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual inhibition of topoisomerase II and microtubule of podophyllotoxin derivative 5p overcomes cancer multidrug resistance.
    Lv X; Cheng WH; Li XX; Shang H; Zhang JY; Hong HY; Zheng YJ; Dong YQ; Gong JH; Zheng YB; Zou ZM
    Eur J Pharmacol; 2024 Nov; 983():176968. PubMed ID: 39233039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Shankaraiah N; Kumar NP; Amula SB; Nekkanti S; Jeengar MK; Naidu VG; Reddy TS; Kamal A
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4239-44. PubMed ID: 26292628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
    Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.
    Xue X; Qu XJ; Gao ZH; Sun CC; Liu HP; Zhao CR; Cheng YN; Lou HX
    Invest New Drugs; 2012 Feb; 30(1):212-22. PubMed ID: 20924640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GMZ-1 is a podophyllotoxin derivative that suppresses growth and induces apoptosis in adriamycin-resistant K562/A02 cells through modulation of MDR1 expression.
    Cao B; Yang S; Li W; Chen H; Chen Y; Liu Y; Liu B
    Mol Med Rep; 2018 Jan; 17(1):474-478. PubMed ID: 29115592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
    Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adva-27a, a novel podophyllotoxin derivative found to be effective against multidrug resistant human cancer cells.
    Merzouki A; Buschmann MD; Jean M; Young RS; Liao S; Gal S; Li Z; Slilaty SN
    Anticancer Res; 2012 Oct; 32(10):4423-32. PubMed ID: 23060568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel podophyllotoxin derivative (YB-1EPN) induces apoptosis and down-regulates express of P-glycoprotein in multidrug resistance cell line KBV200.
    Chen H; Bi W; Cao B; Yang Z; Chen S; Shang H; Yu P; Yang J
    Eur J Pharmacol; 2010 Feb; 627(1-3):69-74. PubMed ID: 19879873
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor.
    Kadayat TM; Park C; Jun KY; Thapa Magar TB; Bist G; Yoo HY; Kwon Y; Lee ES
    Eur J Med Chem; 2015 Jan; 90():302-14. PubMed ID: 25437617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of a novel artesunate-podophyllotoxin conjugate as anticancer agent.
    Zhang L; Chen F; Zhang Z; Chen Y; Wang J
    Bioorg Med Chem Lett; 2016 Jan; 26(1):38-42. PubMed ID: 26615886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A cysteine-reactive alkyl hydroquinone modifies topoisomerase IIα, enhances DNA breakage, and induces apoptosis in cancer cells.
    Lin TY; Huang CP; Au LC; Chang YW; Hu CY; Lin SB
    Chem Res Toxicol; 2012 Nov; 25(11):2340-51. PubMed ID: 23088786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells.
    Patra N; De U; Kang JA; Kim JM; Ahn MY; Lee J; Jung JH; Chung HY; Moon HR; Kim HS
    Eur J Pharmacol; 2011 May; 658(2-3):98-107. PubMed ID: 21376033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Daurinol, a catalytic inhibitor of topoisomerase IIα, suppresses SNU-840 ovarian cancer cell proliferation through cell cycle arrest in S phase.
    Kang K; Nho CW; Kim ND; Song DG; Park YG; Kim M; Pan CH; Shin D; Oh SH; Oh HS
    Int J Oncol; 2014 Aug; 45(2):558-66. PubMed ID: 24841075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
    Park SE; Chang IH; Jun KY; Lee E; Lee ES; Na Y; Kwon Y
    Eur J Med Chem; 2013 Nov; 69():139-45. PubMed ID: 24013413
    [TBL] [Abstract][Full Text] [Related]  

  • 18. L1EPO, a novel podophyllotoxin derivative overcomes P-glycoprotein-mediated multidrug resistance in K562/A02 cell line.
    Chen H; Wang J; Zhang J; Wang Y; Cao B; Bai S; Yu PF; Bi W; Xie W
    Biol Pharm Bull; 2009 Apr; 32(4):609-13. PubMed ID: 19336892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells.
    Islam MS; Park S; Song C; Kadi AA; Kwon Y; Rahman AF
    Eur J Med Chem; 2017 Jan; 125():49-67. PubMed ID: 27654394
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
    Qin Y; Meng L; Hu C; Duan W; Zuo Z; Lin L; Zhang X; Ding J
    Mol Cancer Ther; 2007 Sep; 6(9):2429-40. PubMed ID: 17876042
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.