BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

579 related articles for article (PubMed ID: 25599948)

  • 81. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
    Liang T; Zhou X; Lu L; Dong H; Zhang Y; Xu Y; Qi J; Zhang Y; Wang J
    Bioorg Chem; 2021 May; 110():104793. PubMed ID: 33770673
    [TBL] [Abstract][Full Text] [Related]  

  • 82. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
    Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
    [TBL] [Abstract][Full Text] [Related]  

  • 83. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U; Urbaniak A; Maj E; Moshari M; Delgado M; Wietrzyk J; Bartl F; Chambers TC; Tuszynski JA; Huczyński A
    Bioorg Chem; 2018 Dec; 81():553-566. PubMed ID: 30248507
    [TBL] [Abstract][Full Text] [Related]  

  • 84. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y; Ruan Y; Cheng B; Li L; Liu J; Fang Y; Chen J
    Bioorg Med Chem; 2021 Sep; 46():116376. PubMed ID: 34455231
    [TBL] [Abstract][Full Text] [Related]  

  • 85. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
    Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
    [TBL] [Abstract][Full Text] [Related]  

  • 86. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G; Liu W; Fan M; He M; Li Y; Peng Z
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1694-1702. PubMed ID: 34309466
    [TBL] [Abstract][Full Text] [Related]  

  • 87. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N; Nekkanti S; Brahma UR; Praveen Kumar N; Deshpande N; Prasanna D; Senwar KR; Jaya Lakshmi U
    Bioorg Med Chem; 2017 Sep; 25(17):4805-4816. PubMed ID: 28774575
    [TBL] [Abstract][Full Text] [Related]  

  • 88. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
    Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
    [TBL] [Abstract][Full Text] [Related]  

  • 89. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
    Zhai M; Wang L; Liu S; Wang L; Yan P; Wang J; Zhang J; Guo H; Guan Q; Bao K; Wu Y; Zhang W
    Eur J Med Chem; 2018 Aug; 156():137-147. PubMed ID: 30006160
    [TBL] [Abstract][Full Text] [Related]  

  • 90. A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
    Al-Hamashi AA; Koranne R; Dlamini S; Alqahtani A; Karaj E; Rashid MS; Knoff JR; Dunworth M; Pflum MKH; Casero RA; Perera L; Taylor WR; Tillekeratne LMV
    Bioorg Chem; 2021 Nov; 116():105297. PubMed ID: 34509798
    [TBL] [Abstract][Full Text] [Related]  

  • 91. Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence.
    Zhu C; Zuo Y; Wang R; Liang B; Yue X; Wen G; Shang N; Huang L; Chen Y; Du J; Bu X
    J Med Chem; 2014 Aug; 57(15):6364-82. PubMed ID: 25061803
    [TBL] [Abstract][Full Text] [Related]  

  • 92. Synthesis of arylpyrazole linked benzimidazole conjugates as potential microtubule disruptors.
    Kamal A; Shaik AB; Polepalli S; Kumar GB; Reddy VS; Mahesh R; Garimella S; Jain N
    Bioorg Med Chem; 2015 Mar; 23(5):1082-95. PubMed ID: 25648686
    [TBL] [Abstract][Full Text] [Related]  

  • 93. Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents.
    Mehndiratta S; Chiang YF; Lai MJ; Lee HY; Chen MC; Kuo CC; Chang CY; Chang JY; Liou JP
    Bioorg Med Chem; 2014 Sep; 22(17):4917-23. PubMed ID: 25059503
    [TBL] [Abstract][Full Text] [Related]  

  • 94. Pyrazoline derivatives as tubulin polymerization inhibitors with one hit for Vascular Endothelial Growth Factor Receptor 2 inhibition.
    Yang B; Zhou J; Wang F; Hu XW; Shi Y
    Bioorg Chem; 2021 Sep; 114():105134. PubMed ID: 34246970
    [TBL] [Abstract][Full Text] [Related]  

  • 95. Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.
    Upadhyaya K; Hamidullah ; Singh K; Arun A; Shukla M; Srivastava N; Ashraf R; Sharma A; Mahar R; Shukla SK; Sarkar J; Ramachandran R; Lal J; Konwar R; Tripathi RP
    Org Biomol Chem; 2016 Jan; 14(4):1338-58. PubMed ID: 26659548
    [TBL] [Abstract][Full Text] [Related]  

  • 96. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
    Padmaja P; Koteswara Rao G; Indrasena A; Subba Reddy BV; Patel N; Shaik AB; Reddy N; Dubey PK; Bhadra MP
    Org Biomol Chem; 2015 Feb; 13(5):1404-14. PubMed ID: 25467166
    [TBL] [Abstract][Full Text] [Related]  

  • 97. Discovery of an indole-substituted furanone with tubulin polymerization inhibition activity.
    Mowery P; Filkorn MM; Hurysz B; Kwansare DO; Lafferty MM; McFadden MA; Neerukonda ND; Patel RR; Pierce K; Sockett KA; Truax NJ; Webster NR; Pelkey ET
    Bioorg Med Chem Lett; 2021 Jun; 41():127991. PubMed ID: 33775833
    [TBL] [Abstract][Full Text] [Related]  

  • 98. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles.
    Wang C; Li Y; Liu T; Wang Z; Zhang Y; Bao K; Wu Y; Guan Q; Zuo D; Zhang W
    Bioorg Chem; 2020 Nov; 104():103909. PubMed ID: 33142419
    [TBL] [Abstract][Full Text] [Related]  

  • 99. 3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.
    Kamal A; Sultana F; Ramaiah MJ; Srikanth YV; Viswanath A; Kishor C; Sharma P; Pushpavalli SN; Addlagatta A; Pal-Bhadra M
    ChemMedChem; 2012 Feb; 7(2):292-300. PubMed ID: 22241597
    [TBL] [Abstract][Full Text] [Related]  

  • 100. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
    Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
    Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.