BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

528 related articles for article (PubMed ID: 25602520)

  • 21. ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage.
    Medhurst AL; Warmerdam DO; Akerman I; Verwayen EH; Kanaar R; Smits VA; Lakin ND
    J Cell Sci; 2008 Dec; 121(Pt 23):3933-40. PubMed ID: 19020305
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO.
    Hara K; Tatsukawa K; Nagata K; Iida N; Hishiki A; Ohashi E; Hashimoto H
    J Biol Chem; 2024 Mar; 300(3):105751. PubMed ID: 38354779
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO.
    Hara K; Hishiki A; Hoshino T; Nagata K; Iida N; Sawada Y; Ohashi E; Hashimoto H
    J Biol Chem; 2023 Apr; 299(4):103061. PubMed ID: 36841485
    [TBL] [Abstract][Full Text] [Related]  

  • 24. APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
    Willis J; Patel Y; Lentz BL; Yan S
    Proc Natl Acad Sci U S A; 2013 Jun; 110(26):10592-7. PubMed ID: 23754435
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.
    Lyndaker AM; Lim PX; Mleczko JM; Diggins CE; Holloway JK; Holmes RJ; Kan R; Schlafer DH; Freire R; Cohen PE; Weiss RS
    PLoS Genet; 2013; 9(2):e1003320. PubMed ID: 23468651
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress.
    Ackerson SM; Gable CI; Stewart JA
    Cell Cycle; 2020 Dec; 19(24):3491-3507. PubMed ID: 33269665
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance.
    Tuul M; Kitao H; Iimori M; Matsuoka K; Kiyonari S; Saeki H; Oki E; Morita M; Maehara Y
    PLoS One; 2013; 8(2):e55361. PubMed ID: 23383325
    [TBL] [Abstract][Full Text] [Related]  

  • 28. S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.
    Wong VC; Cash HL; Morse JL; Lu S; Zhitkovich A
    Cell Cycle; 2012 Jul; 11(13):2526-37. PubMed ID: 22722496
    [TBL] [Abstract][Full Text] [Related]  

  • 29. RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.
    Kar A; Kaur M; Ghosh T; Khan MM; Sharma A; Shekhar R; Varshney A; Saxena S
    Nucleic Acids Res; 2015 May; 43(10):4962-74. PubMed ID: 25916848
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.
    Hassan BH; Lindsey-Boltz LA; Kemp MG; Sancar A
    J Biol Chem; 2013 Jun; 288(26):18903-10. PubMed ID: 23696651
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The Rad4(TopBP1) ATR-activation domain functions in G1/S phase in a chromatin-dependent manner.
    Lin SJ; Wardlaw CP; Morishita T; Miyabe I; Chahwan C; Caspari T; Schmidt U; Carr AM; Garcia V
    PLoS Genet; 2012 Jun; 8(6):e1002801. PubMed ID: 22761595
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
    Kemp MG; Akan Z; Yilmaz S; Grillo M; Smith-Roe SL; Kang TH; Cordeiro-Stone M; Kaufmann WK; Abraham RT; Sancar A; Unsal-Kaçmaz K
    J Biol Chem; 2010 May; 285(22):16562-71. PubMed ID: 20233725
    [TBL] [Abstract][Full Text] [Related]  

  • 33. UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.
    Warmerdam DO; Brinkman EK; Marteijn JA; Medema RH; Kanaar R; Smits VA
    J Cell Sci; 2013 May; 126(Pt 9):1923-30. PubMed ID: 23447674
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event.
    Roos-Mattjus P; Vroman BT; Burtelow MA; Rauen M; Eapen AK; Karnitz LM
    J Biol Chem; 2002 Nov; 277(46):43809-12. PubMed ID: 12228248
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.
    Lindsey-Boltz LA; Serçin O; Choi JH; Sancar A
    J Biol Chem; 2009 Nov; 284(48):33107-14. PubMed ID: 19828454
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects.
    Bao S; Lu T; Wang X; Zheng H; Wang LE; Wei Q; Hittelman WN; Li L
    Oncogene; 2004 Jul; 23(33):5586-93. PubMed ID: 15184880
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Menin localizes to chromatin through an ATR-CHK1 mediated pathway after UV-induced DNA damage.
    Farley SM; Chen G; Guo S; Wang M; A J; Lee F; Lee F; Sawicki M
    J Surg Res; 2006 Jun; 133(1):29-37. PubMed ID: 16690369
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.
    Li DQ; Ohshiro K; Khan MN; Kumar R
    J Biol Chem; 2010 Jun; 285(26):19802-12. PubMed ID: 20427275
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.
    Bai L; Michael WM; Yan S
    Cell Signal; 2014 May; 26(5):857-67. PubMed ID: 24440306
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.
    Shiotani B; Nguyen HD; Håkansson P; Maréchal A; Tse A; Tahara H; Zou L
    Cell Rep; 2013 May; 3(5):1651-62. PubMed ID: 23684611
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 27.