BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 25602762)

  • 1. Design and synthesis of potent and multifunctional aldose reductase inhibitors based on quinoxalinones.
    Qin X; Hao X; Han H; Zhu S; Yang Y; Wu B; Hussain S; Parveen S; Jing C; Ma B; Zhu C
    J Med Chem; 2015 Feb; 58(3):1254-67. PubMed ID: 25602762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationship studies of quinoxaline derivatives as aldose reductase inhibitors.
    Wu B; Yang Y; Qin X; Zhang S; Jing C; Zhu C; Ma B
    ChemMedChem; 2013 Dec; 8(12):1913-7. PubMed ID: 24115741
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel synthesis of nitro-quinoxalinone derivatives as aldose reductase inhibitors.
    Hussain S; Parveen S; Qin X; Hao X; Zhang S; Chen X; Zhu C; Ma B
    Bioorg Med Chem Lett; 2014 May; 24(9):2086-9. PubMed ID: 24726808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An efficient synthesis of quinoxalinone derivatives as potent inhibitors of aldose reductase.
    Yang Y; Zhang S; Wu B; Ma M; Chen X; Qin X; He M; Hussain S; Jing C; Ma B; Zhu C
    ChemMedChem; 2012 May; 7(5):823-35. PubMed ID: 22416050
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of potent and selective aldose reductase inhibitors based on pyridylthiadiazine scaffold.
    Chen X; Yang Y; Ma B; Zhang S; He M; Gui D; Hussain S; Jing C; Zhu C; Yu Q; Liu Y
    Eur J Med Chem; 2011 May; 46(5):1536-44. PubMed ID: 21367494
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 1,2-Benzothiazine 1,1-dioxide carboxylate derivatives as novel potent inhibitors of aldose reductase.
    Chen X; Zhang S; Yang Y; Hussain S; He M; Gui D; Ma B; Jing C; Qiao Z; Zhu C; Yu Q
    Bioorg Med Chem; 2011 Dec; 19(23):7262-9. PubMed ID: 22036211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.
    Stefek M; Snirc V; Djoubissie PO; Majekova M; Demopoulos V; Rackova L; Bezakova Z; Karasu C; Carbone V; El-Kabbani O
    Bioorg Med Chem; 2008 May; 16(9):4908-20. PubMed ID: 18395454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acetic acid derivatives of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide as a novel class of potent aldose reductase inhibitors.
    Chen X; Zhu C; Guo F; Qiu X; Yang Y; Zhang S; He M; Parveen S; Jing C; Li Y; Ma B
    J Med Chem; 2010 Dec; 53(23):8330-44. PubMed ID: 21062005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of C7 modifications on benzothiadiazine-1,1-dioxide derivatives on their inhibitory activity and selectivity toward aldose reductase.
    Zhang S; Chen X; Parveen S; Hussain S; Yang Y; Jing C; Zhu C
    ChemMedChem; 2013 Apr; 8(4):603-13. PubMed ID: 23136050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of new inhibitors of aldose reductase from molecular docking and database screening.
    Rastelli G; Ferrari AM; Costantino L; Gamberini MC
    Bioorg Med Chem; 2002 May; 10(5):1437-50. PubMed ID: 11886806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based optimization of aldose reductase inhibitors originating from virtual screening.
    Eisenmann M; Steuber H; Zentgraf M; Altenkämper M; Ortmann R; Perruchon J; Klebe G; Schlitzer M
    ChemMedChem; 2009 May; 4(5):809-19. PubMed ID: 19301313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.
    Da Settimo F; Primofiore G; Da Settimo A; La Motta C; Simorini F; Novellino E; Greco G; Lavecchia A; Boldrini E
    J Med Chem; 2003 Apr; 46(8):1419-28. PubMed ID: 12672241
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation.
    Chatzopoulou M; Patsilinakos A; Vallianatou T; Prnova MS; Zakelj S; Ragno R; Stefek M; Kristl A; Tsantili-Kakoulidou A; Demopoulos VJ
    Bioorg Med Chem; 2014 Apr; 22(7):2194-207. PubMed ID: 24630695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship.
    Juskova M; Majekova M; Demopoulos V; Stefek M
    Gen Physiol Biophys; 2011 Dec; 30(4):342-9. PubMed ID: 22131315
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors.
    Maccari R; Ottanà R; Curinga C; Vigorita MG; Rakowitz D; Steindl T; Langer T
    Bioorg Med Chem; 2005 Apr; 13(8):2809-23. PubMed ID: 15781392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro evaluation of 5-arylidene-2-thioxo-4-thiazolidinones active as aldose reductase inhibitors.
    Maccari R; Del Corso A; Giglio M; Moschini R; Mura U; Ottanà R
    Bioorg Med Chem Lett; 2011 Jan; 21(1):200-3. PubMed ID: 21129963
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and aldose reductase inhibitory activities of novel O-substituted hydroxyphenylacetic acid derivatives.
    Rakowitz D; Angerer H; Matuszczak B
    Arch Pharm (Weinheim); 2006 Oct; 339(10):547-58. PubMed ID: 17009299
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of aldose reductase inhibition and docking studies of 6'-nitro and 6',6''-dinitrorosmarinic acids.
    Koukoulitsa C; Bailly F; Pegklidou K; Demopoulos VJ; Cotelle P
    Eur J Med Chem; 2010 Apr; 45(4):1663-6. PubMed ID: 20071057
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1-Hydroxypyrazole as a bioisostere of the acetic acid moiety in a series of aldose reductase inhibitors.
    Papastavrou N; Chatzopoulou M; Pegklidou K; Nicolaou I
    Bioorg Med Chem; 2013 Sep; 21(17):4951-7. PubMed ID: 23891165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
    Van Zandt MC; Doan B; Sawicki DR; Sredy J; Podjarny AD
    Bioorg Med Chem Lett; 2009 Apr; 19(7):2006-8. PubMed ID: 19250825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.